Pooled analysis of tanezumab efficacy and safety with subgroup analyses of phase III clinical trials in patients with osteoarthritis pain of the knee or hip

Autor: Tive L, Bello AE, Radin D, Schnitzer TJ, Nguyen H, Brown MT, West CR

Publikováno v: Journal of Pain Research, Vol Volume 12, Pp 975-995 (2019)

Leslie Tive,1 Alfonso E Bello,2 David Radin,3 Thomas J Schnitzer,4 Ha Nguyen,1 Mark T Brown,5 Christine R West5 1Pfizer Inc, New York, NY, USA; 2Illinois Bone and Joint Institute, Glenview, IL, USA; 3Stamford Therapeutics Consortium, Stamford, CT, US

Externí odkaz: https://doaj.org/article/5ad4ff3d55314567ae5cbda7262ed1c7

A Phase II Trial of Lutikizumab, an Anti–Interleukin‐1α/β Dual Variable Domain Immunoglobulin, in Knee Osteoarthritis Patients With Synovitis

Autor: Fleischmann, RM, Bliddal, H, Blanco, FJ, Schnitzer, TJ, Peterfy, C, Chen, S, Wang, L, Feng, S, Conaghan, PG, Berenbaum, F, Pelletier, JP, Martel-Pelletier, J, Vaeterlein, O, Kaeley, GS, Liu, W, Kosloski, MP, Levy, G, Zhang, L, Medema, JK, Levesque, MC

Objective: To assess the efficacy and safety of the anti–interleukin‐1α/β (anti–IL‐1α/β) dual variable domain immunoglobulin lutikizumab (ABT‐981) in patients with knee osteoarthritis (OA) and evidence of synovitis. Methods: Patients (n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::6feb947eb9206097da1386e332a89c99

Corticostriatal functional connectivity predicts transition to chronic back pain

Autor: Fields, Howard, Baliki, MN, Petre, B, Torbey, S, Herrmann, KM, Huang, L, Schnitzer, TJ, Fields, HL, Apkarian, AV

Publikováno v: Fields, Howard; Baliki, MN; Petre, B; Torbey, S; Herrmann, KM; Huang, L; et al.(2012). Corticostriatal functional connectivity predicts transition to chronic back pain. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0996m6gj

The mechanism of brain reorganization in pain chronification is unknown. In a longitudinal brain imaging study, subacute back pain (SBP) patients were followed over the course of 1 year. When pain persisted (SBPp, in contrast to recovering SBP and he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::ae9d0d07d858c39a51b92c16d9a3028e
http://www.escholarship.org/uc/item/0996m6gj

Two-year results of once-weekly administration of alendronate 70 mg for the treatment of postmenopausal osteoporosis

Autor: Greespan, Sl, Iii, Bone G., Schnitzer, Tj, Watts, Nb, Adami, Silvano, Foldes, Aj, Roux, C, Levine, Ma, Uebelhart, B, Santora Ac Ii, Kaur, A, Peverly, Ca, Orloff, J, Rizzoli, R.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1943::ea0890c48d0b96e614f9a1016c2ba661
http://hdl.handle.net/11562/26184

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