Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation.

Autor: Queval CJ; The Francis Crick Institute, London, United Kingdom., Fearns A; The Francis Crick Institute, London, United Kingdom., Botella L; The Francis Crick Institute, London, United Kingdom., Smyth A; UCD School of Veterinary Medicine and UCD Conway Institute, University College Dublin, Dublin, Ireland., Schnettger L; The Francis Crick Institute, London, United Kingdom., Mitermite M; UCD School of Veterinary Medicine and UCD Conway Institute, University College Dublin, Dublin, Ireland., Wooff E; Animal and Plant Health Agency, Addlestone, United Kingdom., Villarreal-Ramos B; Animal and Plant Health Agency, Addlestone, United Kingdom.; Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, United Kingdom., Garcia-Jimenez W; Department of Pathology an Infectious Diseases. School of Veterinary Medicine. University of Surrey, Guildford, United Kingdom., Heunis T; Biosciences Institute, Newcastle University, Newcastle, United Kingdom., Trost M; Biosciences Institute, Newcastle University, Newcastle, United Kingdom., Werling D; Department of Pathobiology and Population Sciences, The Royal Veterinary College, University of London, Hatfield Hertfordshire, United Kingdom., Salguero FJ; Department of Pathology an Infectious Diseases. School of Veterinary Medicine. University of Surrey, Guildford, United Kingdom.; National Infection Service, Public Health England (PHE), Porton Down, Salisbury, United Kingdom., Gordon SV; UCD School of Veterinary Medicine and UCD Conway Institute, University College Dublin, Dublin, Ireland., Gutierrez MG; The Francis Crick Institute, London, United Kingdom.

Publikováno v: PLoS pathogens [PLoS Pathog] 2021 Mar 15; Vol. 17 (3), pp. e1009410. Date of Electronic Publication: 2021 Mar 15 (Print Publication: 2021).

Retrospective Single Nucleotide Polymorphism Analysis of Host Resistance and Susceptibility to Ovine Johne's Disease Using Restored FFPE DNA.

Autor: Kravitz, Amanda¹ (AUTHOR) akravitz@vt.edu, Liao, Mingsi² (AUTHOR), Morota, Gota² (AUTHOR), Tyler, Ron¹ (AUTHOR), Cockrum, Rebecca² (AUTHOR), Manohar, B. Murali³ (AUTHOR), Ronald, B. Samuel Masilamoni³ (AUTHOR), Collins, Michael T.⁴ (AUTHOR), Sriranganathan, Nammalwar¹ (AUTHOR) akravitz@vt.edu

Publikováno v: International Journal of Molecular Sciences. Jul2024, Vol. 25 Issue 14, p7748. 19p.

A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity.

Autor: Schnettger L; Host-Pathogen Interactions In Tuberculosis Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Rodgers A; Mycobacterial Systems Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Repnik U; Department of Biosciences, University of Oslo, Blindernveien 31, 0371 Oslo, Norway., Lai RP; Tuberculosis Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Pei G; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany., Verdoes M; Radboud Institute for Molecular Life Sciences (RIMLS), Geert Grooteplein 26/28, Nijmegen 6525 GA, the Netherlands., Wilkinson RJ; Tuberculosis Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Young DB; Mycobacterial Systems Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Gutierrez MG; Host-Pathogen Interactions In Tuberculosis Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address: max.g@crick.ac.uk.

Publikováno v: Cell host & microbe [Cell Host Microbe] 2017 May 10; Vol. 21 (5), pp. 619-628.e5.

The Role of Rab GTPases in the development of genetic and malignant diseases.

Autor: Erol ÖD; Department of Stem Cell Sciences, Hacettepe University Graduate School of Health Sciences, 06100, Ankara, Turkey.; Hacettepe University Center for Stem Cell Research and Development, 06100, Ankara, Turkey., Şenocak Ş; Department of Stem Cell Sciences, Hacettepe University Graduate School of Health Sciences, 06100, Ankara, Turkey.; Hacettepe University Center for Stem Cell Research and Development, 06100, Ankara, Turkey., Aerts-Kaya F; Department of Stem Cell Sciences, Hacettepe University Graduate School of Health Sciences, 06100, Ankara, Turkey. fatimaaerts@yahoo.com.; Hacettepe University Center for Stem Cell Research and Development, 06100, Ankara, Turkey. fatimaaerts@yahoo.com.

Publikováno v: Molecular and cellular biochemistry [Mol Cell Biochem] 2024 Feb; Vol. 479 (2), pp. 255-281. Date of Electronic Publication: 2023 Apr 15.

Beta-2 adrenergic receptor agonism alters astrocyte phagocytic activity and has potential applications to psychiatric disease.

Autor: Bowen, Ellen R.^1,2,3 (AUTHOR), DiGiacomo, Phillip¹ (AUTHOR), Fraser, Hannah P.¹ (AUTHOR), Guttenplan, Kevin^1,4 (AUTHOR), Smith, Benjamin A. H.¹ (AUTHOR), Heberling, Marlene L.¹ (AUTHOR), Vidano, Laura⁵ (AUTHOR), Shah, Nigam⁶ (AUTHOR), Shamloo, Mehrdad⁵ (AUTHOR), Wilson, Jennifer L.^1,7 (AUTHOR) jenniferwilson@ucla.edu, Grimes, Kevin V.¹ (AUTHOR) kgrimes@stanford.edu

Publikováno v: Discover Mental Health. 11/30/2023, Vol. 3 Issue 1, p1-20. 20p.