Cryo-EM structure of cell-free synthesized human histamine 2 receptor/Gs complex in nanodisc environment.

Autor: Köck, Zoe, Schnelle, Kilian, Persechino, Margherita, Umbach, Simon, Schihada, Hannes, Januliene, Dovile, Parey, Kristian, Pockes, Steffen, Kolb, Peter, Dötsch, Volker, Möller, Arne, Hilger, Daniel, Bernhard, Frank

Publikováno v: Nature Communications; 1/2/2024, Vol. 15 Issue 1, p1-15, 15p

Cryo-EM structure of cell-free synthesized human histamine 2 receptor/G s complex in nanodisc environment.

Autor: Köck Z; Centre for Biomolecular Magnetic Resonance, Institute for Biophysical Chemistry, Goethe-University of Frankfurt/Main, Frankfurt, Germany., Schnelle K; Department of Biology/Chemistry, Structural Biology section, University of Osnabrück, Osnabrück, Germany.; Center of Cellular Nanoanalytic Osnabrück (CellNanOs), University of Osnabrück, Osnabrück, Germany., Persechino M; Department of Pharmaceutical Chemistry, University of Marburg, Marburg, Germany., Umbach S; Centre for Biomolecular Magnetic Resonance, Institute for Biophysical Chemistry, Goethe-University of Frankfurt/Main, Frankfurt, Germany., Schihada H; Department of Pharmaceutical Chemistry, University of Marburg, Marburg, Germany., Januliene D; Department of Biology/Chemistry, Structural Biology section, University of Osnabrück, Osnabrück, Germany.; Center of Cellular Nanoanalytic Osnabrück (CellNanOs), University of Osnabrück, Osnabrück, Germany., Parey K; Department of Biology/Chemistry, Structural Biology section, University of Osnabrück, Osnabrück, Germany.; Center of Cellular Nanoanalytic Osnabrück (CellNanOs), University of Osnabrück, Osnabrück, Germany., Pockes S; Institute of Pharmacy, University of Regensburg, Regensburg, Germany., Kolb P; Department of Pharmaceutical Chemistry, University of Marburg, Marburg, Germany., Dötsch V; Centre for Biomolecular Magnetic Resonance, Institute for Biophysical Chemistry, Goethe-University of Frankfurt/Main, Frankfurt, Germany., Möller A; Department of Biology/Chemistry, Structural Biology section, University of Osnabrück, Osnabrück, Germany. arne.moeller@uni-osnabrueck.de.; Center of Cellular Nanoanalytic Osnabrück (CellNanOs), University of Osnabrück, Osnabrück, Germany. arne.moeller@uni-osnabrueck.de., Hilger D; Department of Pharmaceutical Chemistry, University of Marburg, Marburg, Germany. daniel.hilger@pharmazie.uni-marburg.de., Bernhard F; Centre for Biomolecular Magnetic Resonance, Institute for Biophysical Chemistry, Goethe-University of Frankfurt/Main, Frankfurt, Germany. fbern@bpc.uni-frankfurt.de.

Publikováno v: Nature communications [Nat Commun] 2024 Feb 28; Vol. 15 (1), pp. 1831. Date of Electronic Publication: 2024 Feb 28.