Výsledky vyhledávání - "Schneggenburger R"

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RIM1 and RIM2 redundantly determine Ca2+ channel density and readily releasable pool size at a large hindbrain synapse

Autor: Han Y., Babai N., Kaeser P., Sudhof T. C., Schneggenburger R.

Publikováno v: Journal of Neurophysiology

The localization and density of voltage gated Ca(2+) channels at active zones are essential for the amount and kinetics of transmitter release at synapses. RIM proteins are scaffolding proteins at the active zone that bind to several other presynapti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=snsf_p3_pubs::2ff26e97c442164b2e3c348af179a0a9
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380487/

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Molecular mechanisms governing Ca(2+) regulation of evoked and spontaneous release

Autor: Schneggenburger R., Rosenmund C.

Publikováno v: Nature neuroscience

The relationship between transmitter release evoked by action potentials and spontaneous release has fascinated neuroscientists for half a century and separate biological roles for spontaneous release are emerging. Nevertheless separate functions for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=snsf_p3_pubs::a1d7a29395e13f2760f41fccfb802f60
http://lsym.epfl.ch/files/content/sites/lsym/files/shared/Publications/2015/Release_Review_11_OpenAc

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An alien divalent ion reveals a major role for Ca2+ buffering in controlling slow transmitter release

Autor: Babai N., Kochubey O., Keller D., Schneggenburger R.

Publikováno v: J Neurosci

Ca(2+) dependent transmitter release occurs in a fast and in a slow phase but the differential roles of Ca(2+) buffers and Ca(2+) sensors in shaping release kinetics are still controversial. Replacing extracellular Ca(2+) by Sr(2+) causes decreased f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=snsf_p3_pubs::1ad864c0f92c82bbfbc4f31e2a90ad31

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Developmental regulation of the intracellular Ca2+ sensitivity of vesicle fusion and Ca2+-secretion coupling at the rat calyx of Held

Autor: Kochubey O., Han Y., Schneggenburger R.

Publikováno v: J Physiol

Developmental refinement of synaptic transmission can occur via changes in several pre and postsynaptic factors but it has been unknown whether the intrinsic Ca2+ sensitivity of vesicle fusion in the nerve terminal can be regulated during development

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=snsf_p3_pubs::b2a84c73b2aedbd74f285a011c3f0078
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718258/

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Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C

Autor: Lou X., Korogod N., Brose N., Schneggenburger R.

Publikováno v: J Neurosci

Diacylglycerol (DAG) and phorbol esters strongly potentiate transmitter release at synapses by activating protein kinase C (PKC) and members of the Munc13 family of presynaptic vesicle priming proteins. This PKC/Munc13 pathway has emerged as a crucia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=snsf_p3_pubs::eda4dd16d1453932f82848086160af01
http://lsym.epfl.ch/files/content/sites/lsym/files/shared/Publications/2008/Lou_Schneggenburger08.pd

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A limited contribution of Ca2+ current facilitation to paired-pulse facilitation of transmitter release at the rat calyx of Held

Autor: Muller M., Felmy F., Schneggenburger R.

Publikováno v: J Physiol

Recent studies have suggested that transmitter release facilitation at synapses is largely mediated by presynaptic Ca(2+) current facilitation but the exact contribution of Ca(2+) current facilitation has not been determined quantitatively. Here we d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=snsf_p3_pubs::840591700977ad1bbb9958ef4813d6dd
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655367/

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Kniha

Ca2 +-Sensitivity of Vesicle Fusion

Autor: Kochubey, O., Schneggenburger, R.

Publikováno v: In Reference Module in Biomedical Research 2014

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