Heparan Sulfate-dependent RAGE oligomerization is indispensable for pathophysiological functions of RAGE

Autor: Ashwni Verma, Ong Cy, Tan L, Langouet-Astrie Cj, Dhaval K. Shah, Yang Y, Schmidt Ep, Miaomiao Li, Ding Xu, Xiaoyu Zhang

RAGE, a druggable inflammatory receptor, is known to function as an oligomer but the exact oligomerization mechanism remains poorly understood. Previously we have shown that heparan sulfate (HS) plays an active role in RAGE oligomerization. To unders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::982fe920a569328d121f832db55f4d57
https://doi.org/10.1101/2021.06.17.448852

Hyperoxia and apoptosis: too much of a good thing?

Autor: Tuder RM, Hunt JM, Schmidt EP

Publikováno v: American Journal of Respiratory & Critical Care Medicine; 4/15/2011, Vol. 183 Issue 8, p964-965, 2p

Images in clinical medicine. Toxic neutrophils in Streptococcus pneumoniae sepsis.

Autor: Hann CL (AUTHOR), Schmidt EP (AUTHOR)

Publikováno v: New England Journal of Medicine. 12/16/2004, Vol. 351 Issue 25, p2636-2636. 1p.

CIRCULATING HEPARAN SULFATE PROFILES IN PEDIATRIC ACUTE RESPIRATORY DISTRESS SYNDROME.

Autor: Sallee CJ; Department of Pediatrics, Division of Pediatric Critical Care Medicine, David Geffen School of Medicine at University of California Los Angeles and Mattel Children's Hospital, Los Angeles, California., Maddux AB; Department of Pediatrics, Section of Pediatric Critical Care, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado., Hippensteel JA; Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Markovic D; Department of Medicine, Biostatistics Core, University of California Los Angeles, Los Angeles, California., Oshima K; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Schwingshackl A; Department of Pediatrics, Division of Pediatric Critical Care Medicine, David Geffen School of Medicine at University of California Los Angeles and Mattel Children's Hospital, Los Angeles, California., Mourani PM; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock, Arkansas., Schmidt EP; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Sapru A; Department of Pediatrics, Division of Pediatric Critical Care Medicine, David Geffen School of Medicine at University of California Los Angeles and Mattel Children's Hospital, Los Angeles, California.

Publikováno v: Shock (Augusta, Ga.) [Shock] 2024 Oct 01; Vol. 62 (4), pp. 496-504.

Matrix metalloproteinases mediate influenza A-associated shedding of the alveolar epithelial glycocalyx.

Autor: Schaaf KR; Vanderbilt University, Nashville, Tennessee, United States of America.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Landstreet SR; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Putz ND; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Gonski SK; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Lin J; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Buggs CJ; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Gibson D; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Langouët-Astrié CJ; Division of Pulmonary and Critical Care, Department of Medicine, University of Colorado Anschutz, Denver, Colorado, United States of America., Jetter CS; Department of Neonatology, Monroe Caroll Children's Hospital at Vanderbilt, Nashville, Tennessee, United States of America., Negretti NM; Department of Neonatology, Monroe Caroll Children's Hospital at Vanderbilt, Nashville, Tennessee, United States of America., Sucre JMS; Department of Neonatology, Monroe Caroll Children's Hospital at Vanderbilt, Nashville, Tennessee, United States of America., Schmidt EP; Division of Pulmonary and Critical Care, Department of Medicine, University of Colorado Anschutz, Denver, Colorado, United States of America.; Division of Pulmonary and Critical Care, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America., Ware LB; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Bastarache JA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Department of Cell and Development Biology, Vanderbilt University, Nashville, Tennessee, United States of America., Shaver CM; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.

Publikováno v: PloS one [PLoS One] 2024 Sep 23; Vol. 19 (9), pp. e0308648. Date of Electronic Publication: 2024 Sep 23 (Print Publication: 2024).