A self-organized synthetic morphogenic liposome responds with shape changes to local light cues.

Autor: Gavriljuk K; Department of Systemic Cell Biology, Max Planck Institute for Molecular Physiology, Dortmund, Germany., Scocozza B; Department of Systemic Cell Biology, Max Planck Institute for Molecular Physiology, Dortmund, Germany., Ghasemalizadeh F; Department of Systemic Cell Biology, Max Planck Institute for Molecular Physiology, Dortmund, Germany., Seidel H; Department of Systemic Cell Biology, Max Planck Institute for Molecular Physiology, Dortmund, Germany., Nandan AP; Department of Systemic Cell Biology, Max Planck Institute for Molecular Physiology, Dortmund, Germany.; Cellular Computations and Learning, Center of Advanced European Studies and Research (caesar), Bonn, Germany., Campos-Medina M; Department of Systemic Cell Biology, Max Planck Institute for Molecular Physiology, Dortmund, Germany., Schmick M; Department of Systemic Cell Biology, Max Planck Institute for Molecular Physiology, Dortmund, Germany., Koseska A; Department of Systemic Cell Biology, Max Planck Institute for Molecular Physiology, Dortmund, Germany.; Cellular Computations and Learning, Center of Advanced European Studies and Research (caesar), Bonn, Germany., Bastiaens PIH; Department of Systemic Cell Biology, Max Planck Institute for Molecular Physiology, Dortmund, Germany. philippe.bastiaens@mpi-dortmund.mpg.de.; Faculty of Chemistry and Chemical Biology, TU Dortmund, Dortmund, Germany. philippe.bastiaens@mpi-dortmund.mpg.de.

Publikováno v: Nature communications [Nat Commun] 2021 Mar 09; Vol. 12 (1), pp. 1548. Date of Electronic Publication: 2021 Mar 09.

Novel druggable space in human KRAS G13D discovered using structural bioinformatics and a P-loop targeting monoclonal antibody.

Autor: Jungholm, Oscar¹, Trkulja, Carolina^2,3, Moche, Martin⁴, Srinivasa, Sreesha P.^2,5, Christakopoulou, Maria-Nefeli¹, Davidson, Max², Reymer, Anna^2,6, Jardemark, Kent¹, Fogaça, Rafaela Lenza², Ashok, Anaswara², Jeffries, Gavin³, Ampah-Korsah, Henry⁴, Strandback, Emilia⁴, Andréll, Juni⁴, Nyman, Tomas⁴, Nouairia, Ghada⁷, Orwar, Owe^1,2 owe.orwar@ki.se

Publikováno v: Scientific Reports. 8/23/2024, Vol. 14 Issue 1, p1-13. 13p.

Spatial cycles mediated by UNC119 solubilisation maintain Src family kinases plasma membrane localisation.

Autor: Konitsiotis AD; Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, 44227, Germany., Roßmannek L; Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, 44227, Germany., Stanoev A; Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, 44227, Germany., Schmick M; Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, 44227, Germany., Bastiaens PIH; Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, 44227, Germany. philippe.bastiaens@mpi-dortmund.mpg.de.; Faculty of Chemistry and Chemical Biology, Technical University of Dortmund, Dortmund, 44227, Germany. philippe.bastiaens@mpi-dortmund.mpg.de.

Publikováno v: Nature communications [Nat Commun] 2017 Jul 24; Vol. 8 (1), pp. 114. Date of Electronic Publication: 2017 Jul 24.

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GOLGA7 is essential for NRAS trafficking from the Golgi to the plasma membrane but not for its palmitoylation.

Autor: Liu, Chenxuan¹ (AUTHOR), Jiao, Bo¹ (AUTHOR), Wang, Peihong¹ (AUTHOR), Zhang, Baoyuan¹ (AUTHOR), Gao, Jiaming¹ (AUTHOR), Li, Donghe¹ (AUTHOR), Xie, Xi¹ (AUTHOR), Yao, Yunying¹ (AUTHOR), Yan, Lei¹ (AUTHOR), Qin, Zhenghong² (AUTHOR), Liu, Ping¹ (AUTHOR) liupingjize@126.com, Ren, Ruibao^1,3 (AUTHOR) rbren@sjtu.edu.cn

Publikováno v: Cell Communication & Signaling. 2/5/2024, Vol. 22 Issue 1, p1-15. 15p.