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DNA copy number motifs are strong and independent predictors of survival in breast cancer

Autor: Pladsen, A.V., Nilsen, G., Rueda, O.M., Aure, M.R., Borgan, Ø., Liestøl, K., Vitelli, V., Frigessi, A., Langerød, A., Mathelier, A., Bathen, T.F., Borgen, E., Børresen-Dale, A.-L., Engebråten, O., Fritzman, B., Garred, Ø., Geisler, J., Geitvik, G.A., Hofvind, S., Kristensen, V., Kåresen, R., Lingjærde, O.C., Mælandsmo, G.M., Naume, B., Russnes, H.G., Sahlberg, K.K., Sauer, T., Skjerven, H.K., Schlichting, E., Sørlie, T., Wedge, D.C., Van Loo, P., Caldas, C.

Publikováno v: Communications Biology, Vol 3, Iss 1, Pp 1-9 (2020)
Communications Biology
Pladsen, A V, Nilsen, G, Rueda, O M, Aure, M R, Borgan, Ø, Liestøl, K, Vitelli, V, Frigessi, A, Langerød, A, Mathelier, A, Bathen, T F, Borgen, E, Børresen-Dale, A-L, Engebråten, O, Fritzman, B, Garred, Ø, Geisler, J, Geitvik, G A, Hofvind, S, Kristensen, V, Kåresen, R, Langerød, A, Lingjærde, O C, Mælandsmo, G M, Naume, B, Russnes, H G, Sahlberg, K K, Sauer, T, Skjerven, H K, Schlichting, E, Sørlie, T, Engebråten, O, Kristensen, V, Wedge, D C, Van Loo, P, Caldas, C, Børresen-Dale, A-L, Russnes, H G & Lingjærde, O C 2020, ' DNA copy number motifs are strong and independent predictors of survival in breast cancer ', Communications Biology . https://doi.org/10.1038/s42003-020-0884-6

Somatic copy number alterations are a frequent sign of genome instability in cancer. A precise characterization of the genome architecture would reveal underlying instability mechanisms and provide an instrument for outcome prediction and treatment g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5b4c6b23b56e53a560f2b4a882bac7
http://link.springer.com/article/10.1038/s42003-020-0884-6