Výsledky vyhledávání - "Schlagwein N"

Properdin produced by dendritic cells contributes to the activation of T cells

Autor: Essen, M.F. van, Schlagwein, N., Gijlswijk-Janssen, D.J. van, Ruben, J.M., Kooten, C. van, COMBAT Consortium

Publikováno v: Immunobiology, 227(4). ELSEVIER GMBH

The complement system does not only play an important role in the defence against microorganism and pathogens, but also contributes to the regulation of innate and adaptive immunity. Especially activation fragments C3a and C5a and complement activati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f041d1c39ca8cd3876ff015c079d1e28
https://hdl.handle.net/1887/3563169

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Akademický článek

Mannan-Binding Lectin Mediates Renal Ischemia/Reperfusion Injury Independent of Complement Activation

Autor: van der Pol, P., Schlagwein, N., van Gijlswijk, D.J., Berger, S.P., Roos, A., Bajema, I.M., de Boer, H.C., de Fijter, J.W., Stahl, G.L., Daha, M.R., van Kooten, C. ^*

Publikováno v: In American Journal of Transplantation April 2012 12(4):877-887

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Initial properdin binding contributes to alternative pathway activation at the surface of viable and necrotic cells

Autor: Essen, M.F. van, Schlagwein, N., Hoven, E.M.P. van den, Gijlswijk-Janssen, D.J. van, Lubbers, R., Bos, R.M. van den, Born, J. van den, Ruben, J.M., Trouw, L.A., Kooten, C. van, COMBAT Consortium

Publikováno v: European Journal of Immunology, 52(4), 597-608. Wiley

Properdin, the only known positive regulator of the complement system, stabilizes the C3 convertase, thereby increasing its half-life. In contrast to most other complement factors, properdin is mainly produced extrahepatically by myeloid cells. Recen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457c170225e520a756672f99672d70dc
https://pubmed.ncbi.nlm.nih.gov/35092629

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Akademický článek

Preferential production and secretion of the complement regulator factor H-like protein 1 (FHL-1) by human myeloid cells.

Autor: van Essen MF; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: m.f.van_essen@lumc.nl., Peereboom ETM; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., Schlagwein N; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., van Gijlswijk-Janssen DJ; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., Nelemans T; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., Joeloemsingh JV; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., van den Berg CW; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., Prins J; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., Clark SJ; Institute for Ophthalmic Research, Eberhard Karls University of Tübingen, Tübingen, Baden-Württemberg 72076, Germany; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom., Schmidt CQ; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, Ulm, Germany., Trouw LA; Department of Immunology, Leiden University Medical Center, Leiden, the Netherlands., van Kooten C; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: c.van_kooten@lumc.nl.

Publikováno v: Immunobiology [Immunobiology] 2023 May; Vol. 228 (3), pp. 152364. Date of Electronic Publication: 2023 Feb 28.

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Akademický článek

Properdin produced by dendritic cells contributes to the activation of T cells.

Autor: van Essen MF; Div of Nephrology and Transplant Medicine, Dept. of Medicine, Leiden University Medical Center, Leiden, The Netherlands., Schlagwein N; Div of Nephrology and Transplant Medicine, Dept. of Medicine, Leiden University Medical Center, Leiden, The Netherlands., van Gijlswijk-Janssen DJ; Div of Nephrology and Transplant Medicine, Dept. of Medicine, Leiden University Medical Center, Leiden, The Netherlands., Ruben JM; Div of Nephrology and Transplant Medicine, Dept. of Medicine, Leiden University Medical Center, Leiden, The Netherlands., van Kooten C; Div of Nephrology and Transplant Medicine, Dept. of Medicine, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: kooten@lumc.nl.

Publikováno v: Immunobiology [Immunobiology] 2022 Jul; Vol. 227 (4), pp. 152246. Date of Electronic Publication: 2022 Jul 09.

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Culture medium used during small interfering RNA (siRNA) transfection determines the maturation status of dendritic cells

Autor: Essen, M.F. van, Schlagwein, N., Gijlswijk-Janssen, D.J. van, Anholts, J.D.H., Eikmans, M., Ruben, J.M., Kooten, C. van, COMBAT Consortium

Publikováno v: Journal of Immunological Methods, 479. ELSEVIER

Gene silencing using small interfering ribonucleic acids (siRNA) is a powerful method to interfere with gene expression, allowing for the functional exploration of specific genes. siRNA interference can be applied in both cell lines, as well as in pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b1603fa1522810afff4e2a09d43f86
https://doi.org/10.1016/j.jim.2020.112748

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Akademický článek

Initial properdin binding contributes to alternative pathway activation at the surface of viable and necrotic cells.

Autor: van Essen MF; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands., Schlagwein N; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands., van den Hoven EMP; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands., van Gijlswijk-Janssen DJ; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands., Lubbers R; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands., van den Bos RM; Faculty of Science, Department of Chemistry, Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands., van den Born J; Department of Nephrology, University Medical Center Groningen, Groningen, The Netherlands., Ruben JM; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands., Trouw LA; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands., van Kooten C; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.

Publikováno v: European journal of immunology [Eur J Immunol] 2022 Apr; Vol. 52 (4), pp. 597-608. Date of Electronic Publication: 2022 Feb 17.

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