BIRC6 (APOLLON) is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation

Autor: Schläfli Anna M, Torbett Bruce E, Fey Martin F, Tschan Mario P

Publikováno v: Experimental Hematology & Oncology, Vol 1, Iss 1, p 25 (2012)

Abstract Background Inhibitors of apoptosis (IAPs) were intensively investigated in the context of cancer where they promote tumor growth and chemoresistence. Overexpression of the IAP BIRC6 is associated with unfavorable clinical features and negati

Externí odkaz: https://doaj.org/article/5b2050a86f7f4c088fcfd530a51f511b

Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions

Autor: Seiler, Kristina, Humbert, Magali, Minder, Petra, Mashimo, Iris, Schläfli, Anna M, Krauer, Deborah, Federzoni, Elena A, Vu, Bich, Moresco, James J, Yates, John R, Sadowski, Martin C, Radpour, Ramin, Kaufmann, Thomas, Sarry, Jean-Emmanuel, Dengjel, Joern, Tschan, Mario P, Torbett, Bruce E

Publikováno v: Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w

The family of hexokinases (HKs) catalyzes the first step of glycolysis, the ATP-dependent phosphorylation of glucose to glucose-6-phosphate. While HK1 and HK2 are ubiquitously expressed, the less well-studied HK3 is primarily expressed in hematopoiet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b661326dbf1c3bb39048246a8e2fcbca
https://boris.unibe.ch/169962/1/s41419-022-04891-w.pdf

The Multifaceted Functions of Autophagy in Breast Cancer Development and Treatment

Autor: Niklaus, Nicolas J, Tokarchuk, Igor, Zbinden, Mara, Schläfli, Anna M, Maycotte, Paola, Tschan, Mario P.

Publikováno v: Cells, Vol 10, Iss 1447, p 1447 (2021)
Niklaus, Nicolas J; Tokarchuk, Igor; Zbinden, Mara; Schläfli, Anna M; Maycotte, Paola; Tschan, Mario P. (2021). The Multifaceted Functions of Autophagy in Breast Cancer Development and Treatment. Cells, 10(6) MDPI 10.3390/cells10061447
Cells

Macroautophagy (herein referred to as autophagy) is a complex catabolic process characterized by the formation of double-membrane vesicles called autophagosomes. During this process, autophagosomes engulf and deliver their intracellular content to ly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687f60ae998086cb3386545a04dcca0b
https://www.mdpi.com/2073-4409/10/6/1447

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