Condensation of the fusion focus by the intrinsically disordered region of the formin Fus1 is essential for cell-cell fusion

Autor: Ingrid Billault-Chaumartin, Olivia Muriel, Laetitia Michon, Sophie G Martin

Publikováno v: Current biology, vol. 32, no. 21, pp. 4752-4761.e10
bioRxiv
BioRxiv

Secretory vesicle clusters transported on actin filaments by myosin V motors for local secretion underlie various cellular processes, such as neurotransmitter release at neuronal synapses, 1 hyphal steering in filamentous fungi, 2 , 3 and local cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd0d1bbe7438bd479da8553c613d8c7
https://doi.org/10.1101/2022.05.05.490810

Optogenetics reveals Cdc42 local activation by scaffold-mediated positive feedback and Ras GTPase

Autor: Vincent Vincenzetti, Laura Merlini, Iker Lamas, Sophie G. Martin, Aleksandar Vjestica

Publikováno v: PLoS biology, vol. 18, no. 1, pp. e3000600
PLoS Biology, Vol 18, Iss 1, p e3000600 (2020)
PLoS Biology

Local activity of the small GTPase Cdc42 is critical for cell polarization. Whereas scaffold-mediated positive feedback was proposed to break symmetry of budding yeast cells and produce a single zone of Cdc42 activity, the existence of similar regula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545d82465c5c718399779415d9725133

Bases of antisense lncRNA-associated regulation of gene expression in fission yeast

Autor: Valérie Migeot, Marc Descrimes, Mayuko Yoda, Maxime Wery, Damien Hermand, Camille Gautier, Antonin Morillon

Publikováno v: PLoS Genetics
PLoS Genetics, Public Library of Science, 2018, 14 (7), pp.e1007465. ⟨10.1371/journal.pgen.1007465⟩
Wery, M, Gautier, C, Descrimes, M, Yoda, M, Migeot, V, Hermand, D & Morillon, A 2018, ' Bases of antisense lncRNA-associated regulation of gene expression in fission yeast ', PLoS Genetics, vol. 14, no. 7, e1007465, pp. e1007465 . https://doi.org/10.1371/journal.pgen.1007465
PLoS Genetics, Vol 14, Iss 7, p e1007465 (2018)

Antisense (as)lncRNAs can regulate gene expression but the underlying mechanisms and the different cofactors involved remain unclear. Using Native Elongating Transcript sequencing, here we show that stabilization of antisense Exo2-sensitivite lncRNAs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb39484308f0058e70f475aa27b83419
https://hal.archives-ouvertes.fr/hal-02349807/document

Inhibition of Ras activity coordinates cell fusion with cell-cell contact during yeast mating

Autor: Bita Khalili, Laura Merlini, Omaya Dudin, Sophie G. Martin, Laetitia Michon, Vincent Vincenzetti

Publikováno v: The Journal of Cell Biology
The Journal of cell biology, vol. 217, no. 4, pp. 1467-1483

The yeast cell wall is digested to allow cell fusion during sexual reproduction. How cells coordinate this process with cell–cell contact to prevent lysis is unclear. Merlini et al. show that the Ras GAP protein Gap1, which is recruited to sites of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86bebe0d0c5ef04040d030b4a2187f6d
https://pubmed.ncbi.nlm.nih.gov/29453312

Three novel antibiotic marker cassettes for gene disruption and marker switching inSchizosaccharomyces pombe

Autor: Pierre Hentges, Lionel Tafforeau, Antony M. Carr, Jean Vandenhaute, Benoît Van Driessche

Publikováno v: Yeast, 22 (13

The ease of construction of multiple mutant strains in Schizosaccharomyces pombe is limited by the number of available genetic markers. We describe here three new cassettes for PCR-mediated gene disruption that can be used in combination with commonl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e947277666685d13c19caf30be5f02
https://doi.org/10.1002/yea.1291