3,3',5,5'-Tetramethoxybiphenyl-4,4'diol triggers oxidative stress, metabolic changes, and apoptosis-like process by reducing the PI3K/AKT/NF-κB pathway in the NCI-H460 lung cancer cell line.

Autor: Concato-Lopes VM; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil. Electronic address: vir_93_@hotmail.com., Silva TF; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil., Detoni MB; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil., Cruz EMS; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil., Gonçalves MD; Laboratory of Biotransformation and Phytochemical, Department of Chemistry, Center of Exact Sciences, State University of Londrina, PR, Brazil., da Silva Bortoleti BT; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil; Graduate Program in Biosciences and Biotechnology, Carlos Chagas Institute (ICC), Fiocruz, Curitiba, PR, Brazil., Tomiotto-Pellissier F; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil; Graduate Program in Biosciences and Biotechnology, Carlos Chagas Institute (ICC), Fiocruz, Curitiba, PR, Brazil; Department of Medical Pathology, Federal University of Paraná, Curitiba, PR, Brazil., Carloto ACM; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil., Madureira MB; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil., Rodrigues ACJ; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil; Graduate Program in Biosciences and Biotechnology, Carlos Chagas Institute (ICC), Fiocruz, Curitiba, PR, Brazil., Schirmann JG; Laboratory Research of Bioactive Molecules, Department of Chemistry, Center of Exact Sciences, State University of Londrina, PR, Brazil., Barbosa-Dekker AM; Laboratory Research of Bioactive Molecules, Department of Chemistry, Center of Exact Sciences, State University of Londrina, PR, Brazil., Dekker RFH; Federal Technological University of Paraná, Graduate Program in Environmental Engineering, Campus Londrina, Londrina, PR, Brazil., Conchon-Costa I; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil., Panis C; Laboratory of Tumor Biology, State University of West Paraná, Unioeste, Francisco Beltrao, Brazil., Lazarin-Bidóia D; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil., Miranda-Sapla MM; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil., Mantovani MS; Laboratory of Toxicological Genetics, Department of General Biology, Center of Biological Sciences, State University of Londrina, PR, Brazil., Pavanelli WR; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Jan; Vol. 170, pp. 115979. Date of Electronic Publication: 2023 Dec 06.

Electrochemical Characterization of the Laccase-Catalyzed Oxidation of 2,6-Dimethoxyphenol: an Insight into the Direct Electron Transfer by Enzyme and Enzyme-Mediator System.

Autor: Mattos GJ; Centro de Ciências Exatas, Departamento de Química, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, PR 445, Km 380, Cx.P. 10.011, CEP: 86057-970, Londrina, PR, Brazil. gabriel.junquetti@uel.br., Schirmann JG; Centro de Ciências Exatas, Departamento de Química, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, PR 445, Km 380, Cx.P. 10.011, CEP: 86057-970, Londrina, PR, Brazil., Salamanca-Neto CAR; Centro de Ciências Exatas, Departamento de Química, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, PR 445, Km 380, Cx.P. 10.011, CEP: 86057-970, Londrina, PR, Brazil., Dekker RFH; Beta-Glucan Produtos Farmoquímicos EIRELI, Universidade Tecnológica Federal Do Paraná, Lote 24A, Bloco Zircônia, Câmpus Londrina, Avenida João Miguel Caram 731, CEP, Londrina, Paraná, 86036-700, Brazil., Barbosa-Dekker AM; Beta-Glucan Produtos Farmoquímicos EIRELI, Universidade Tecnológica Federal Do Paraná, Lote 24A, Bloco Zircônia, Câmpus Londrina, Avenida João Miguel Caram 731, CEP, Londrina, Paraná, 86036-700, Brazil., Sartori ER; Centro de Ciências Exatas, Departamento de Química, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, PR 445, Km 380, Cx.P. 10.011, CEP: 86057-970, Londrina, PR, Brazil. elensartori@uel.br.

Publikováno v: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2022 Oct; Vol. 194 (10), pp. 4348-4361. Date of Electronic Publication: 2022 Feb 11.

Exploring the exocellular fungal biopolymer botryosphaeran for laccase-biosensor architecture and application to determine dopamine and spironolactone.

Autor: Coelho JH; Universidade Estadual de Londrina (UEL), Centro de Ciências Exatas, Departamento de Química, CEP, 86057-970, Londrina, PR, Brazil., Eisele APP; Universidade Estadual de Londrina (UEL), Centro de Ciências Exatas, Departamento de Química, CEP, 86057-970, Londrina, PR, Brazil., Valezi CF; Universidade Estadual de Londrina (UEL), Centro de Ciências Exatas, Departamento de Química, CEP, 86057-970, Londrina, PR, Brazil., Mattos GJ; Universidade Estadual de Londrina (UEL), Centro de Ciências Exatas, Departamento de Química, CEP, 86057-970, Londrina, PR, Brazil., Schirmann JG; Universidade Estadual de Londrina (UEL), Centro de Ciências Exatas, Departamento de Química, CEP, 86057-970, Londrina, PR, Brazil., Dekker RFH; Universidade Tecnológica Federal do Paraná (UTFPR), Programa de Pós-Graduação em Engenharia Ambiental, Câmpus Londrina, CEP, 86036-370, Londrina, PR, Brazil., Barbosa-Dekker AM; Universidade Estadual de Londrina (UEL), Centro de Ciências Exatas, Departamento de Química, CEP, 86057-970, Londrina, PR, Brazil., Sartori ER; Universidade Estadual de Londrina (UEL), Centro de Ciências Exatas, Departamento de Química, CEP, 86057-970, Londrina, PR, Brazil. Electronic address: elensartori@uel.br.

Publikováno v: Talanta [Talanta] 2019 Nov 01; Vol. 204, pp. 475-483. Date of Electronic Publication: 2019 Jun 11.