620 Antisense oligonucleotide splicing modulation as a novel cystic fibrosis therapeutic approach for the N1303 K nonsense mutation

Autor: Oren, Y., Barchad-Avizur, O., Galai, E. Ozeri, Schirelman, M., Blinder, T., Ordan, M., Mordechai, T., Stampfer, C., Cymberknoh, M. Cohen, Kerem, E., Kerem, B.

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A tonic nicotinic brake controls spike timing in striatal spiny projection neurons.

Autor: Matityahu L; Department of Medical Neurobiology, Institute of Medical Research Israel-Canada, The Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Malgady JM; Department of Neurobiology and Behavior, Center for Nervous System Disorders, Stony Brook University School of Medicine, Stony Brook University, Stony Brook, United States., Schirelman M; Department of Medical Neurobiology, Institute of Medical Research Israel-Canada, The Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Johansson Y; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden., Wilking JA; Department of Neurobiology and Behavior, Center for Nervous System Disorders, Stony Brook University School of Medicine, Stony Brook University, Stony Brook, United States., Silberberg G; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden., Goldberg JA; Department of Medical Neurobiology, Institute of Medical Research Israel-Canada, The Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Plotkin JL; Department of Neurobiology and Behavior, Center for Nervous System Disorders, Stony Brook University School of Medicine, Stony Brook University, Stony Brook, United States.

Publikováno v: ELife [Elife] 2022 May 17; Vol. 11. Date of Electronic Publication: 2022 May 17.

Non-uniform distribution of dendritic nonlinearities differentially engages thalamostriatal and corticostriatal inputs onto cholinergic interneurons.

Autor: Oz, Osnat, Matityahu, Lior, Mizrahi-Kliger, Aviv, Kaplan, Alexander, Berkowitz, Noa, Tiroshi, Lior, Bergman, Hagai, Goldberg, Joshua A.

Publikováno v: eLife; 7/21/2022, p1-32, 32p