Výsledky vyhledávání - "Schimer, Jiří"

Report

Nanoscale Dynamic Readout of a Chemical Redox Process Using Radicals Coupled with Nitrogen-Vacancy Centers in Nanodiamonds

Autor: Barton, Jan, Gulka, Michal, Tarabek, Jan, Mindarava, Yuliya, Wang, Zhenyu, Schimer, Jiri, Raabova, Helena, Bednar, Jan, Plenio, Martin B., Jelezko, Fedor, Nesladek, Milos, Cigler, Petr

Publikováno v: ACS Nano 2020, published online 19 August 2020

Biocompatible nanoscale probes for sensitive detection of paramagnetic species and molecules associated with their (bio)chemical transformations would provide a desirable tool for a better understanding of cellular redox processes. Here, we describe

Externí odkaz: http://arxiv.org/abs/2010.11257

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Dissertation/ Thesis

Inhibitory proteas jako nástroj: Návrh, syntéza a testování inhibitorů HIV proteasy a GCPII

Autor: Schimer, Jiří

This dissertation thesis focuses on creating tools for the analysis and potential therapeutic intervention in the biological processes regulated by proteolysis. I focus on two important proteolytic enzymes: HIV-1 protease, which is indispensable for

Externí odkaz: http://www.nusl.cz/ntk/nusl-334607

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Dissertation/ Thesis

Nové inhibitory HIV proteasy: návrh, synthesa a testování aktivity

Autor: Schimer, Jiří

More than 20 years after its discovery HIV protease still remains one of the primary targets in HIV treatment. Currently there are 9 approved protease inhibitors on the market. However, due to immense replication rate and the high error prone nature

Externí odkaz: http://www.nusl.cz/ntk/nusl-297243

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