Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells

Autor: Schild, Achille, Bhardwaj, Rajesh, Wenger, Nicolas, Tscherrig, Dominic, Kandasamy, Palanivel, Dernič, Jan, Baur, Roland, Peinelt, Christine, Hediger, Matthias A., Lochner, Martin

Publikováno v: Schild, Achille; Bhardwaj, Rajesh; Wenger, Nicolas; Tscherrig, Dominic; Kandasamy, Palanivel; Dernič, Jan; Baur, Roland; Peinelt, Christine; Hediger, Matthias A.; Lochner, Martin (2020). Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells. International journal of molecular sciences, 21(16) Molecular Diversity Preservation International MDPI 10.3390/ijms21165604
International Journal of Molecular Sciences, Vol 21, Iss 5604, p 5604 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 16

Calcium ions regulate a wide array of physiological functions including cell differentiation, proliferation, muscle contraction, neurotransmission, and fertilization. The endoplasmic reticulum (ER) is the major intracellular Ca2+ store and cellular e

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