Zobrazeno 1 - 10 of 731 pro vyhledávání: '"Schiering, N"'
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Akademický článek
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2
Akademický článek
Efficient Screening of Target-Specific Selected Compounds in Mixtures by 19 F NMR Binding Assay with Predicted 19 F NMR Chemical Shifts.
Autor: Vulpetti A; Novartis Institutes for BioMedical Research, 4002, Basel, Switzerland., Lingel A; Novartis Institutes for BioMedical Research, 4002, Basel, Switzerland., Dalvit C; Novartis Institutes for BioMedical Research, 4002, Basel, Switzerland., Schiering N; Novartis Institutes for BioMedical Research, 4002, Basel, Switzerland., Oberer L; Novartis Institutes for BioMedical Research, 4002, Basel, Switzerland., Henry C; Novartis Institutes for BioMedical Research, 4002, Basel, Switzerland., Lu Y; Novartis Institutes for BioMedical Research, 5300 Chiron Way, Emeryville, CA 94608, USA.; Present Address: Allorion Therapeutics, 22 Strathmore Road, Natick, MA 01760, USA.
Publikováno v: ChemMedChem [ChemMedChem] 2022 Jul 05; Vol. 17 (13), pp. e202200163. Date of Electronic Publication: 2022 May 12.
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3
Akademický článek
Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach.
Autor: Lorthiois E; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Roache J; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Barnes-Seeman D; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Altmann E; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Hassiepen U; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Turner G; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Duvadie R; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Hornak V; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Karki RG; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Schiering N; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Weihofen WA; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Perruccio F; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Calhoun A; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Fazal T; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Dedic D; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Durand C; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Dussauge S; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Fettis K; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Tritsch F; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Dentel C; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Druet A; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Liu D; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Kirman L; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Lachal J; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Namoto K; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Bevan D; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Mo R; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Monnet G; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Muller L; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Zessis R; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Huang X; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Lindsley L; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Currie T; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Chiu YH; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Fridrich C; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Delgado P; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Wang S; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Hollis-Symynkywicz M; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Berghausen J; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Williams E; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Liu H; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Liang G; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Kim H; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Hoffmann P; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Hein A; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Ramage P; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., D'Arcy A; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Harlfinger S; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Renatus M; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Ruedisser S; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Feldman D; Novartis Institutes for BioMedical Research, East Hanover, New Jersey 07396, United States., Elliott J; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Sedrani R; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Maibaum J; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Adams CM; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Aug 13; Vol. 63 (15), pp. 8088-8113. Date of Electronic Publication: 2020 Jul 21.
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4
Akademický článek
Structure-Guided Design of Substituted Biphenyl Butanoic Acid Derivatives as Neprilysin Inhibitors.
Autor: Kawanami T; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Karki RG; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Cody E; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Liu Q; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Liang G; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Ksander GM; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Rigel DF; Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, New Jersey 07936-1080, United States., Schiering N; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Gong Y; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Coppola GM; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Iwaki Y; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Sun R; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Neubert A; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Fan L; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Ingles S; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., D'Arcy A; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Villard F; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Ramage P; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Jeng AY; Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, New Jersey 07936-1080, United States., Leung-Chu J; Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, New Jersey 07936-1080, United States., Liu J; Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, New Jersey 07936-1080, United States., Beil M; Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, New Jersey 07936-1080, United States., Fu F; Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, New Jersey 07936-1080, United States., Chen W; Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, New Jersey 07936-1080, United States., Cumin F; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Wiesmann C; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Mogi M; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States.
Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2020 Jan 27; Vol. 11 (2), pp. 188-194. Date of Electronic Publication: 2020 Jan 27 (Print Publication: 2020).
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5
Akademický článek
Diagnosis of Prostate Cancer with a Neurotensin–Bombesin Radioligand Combination—First Preclinical Results.
Autor: Bibika, Maria1 (AUTHOR) mp.maria91@hotmail.com, Kanellopoulos, Panagiotis1 (AUTHOR) kanelospan@gmail.com, Rouchota, Maritina2 (AUTHOR) mrouchota@bioemtech.com, Loudos, George2 (AUTHOR) george@bioemtech.com, Nock, Berthold A.1 (AUTHOR) nock_berthold.a@hotmail.com, Krenning, Eric P.3 (AUTHOR) erickrenning@gmail.com, Maina, Theodosia1 (AUTHOR) maina_thea@hotmail.com
Publikováno v: Pharmaceutics. Sep2024, Vol. 16 Issue 9, p1223. 17p.
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6
Akademický článek
Horizontal gene transfer of the Mer operon is associated with large effects on the transcriptome and increased tolerance to mercury in nitrogen-fixing bacteria.
Autor: Bhat, Aditi1 (AUTHOR), Sharma, Reena1 (AUTHOR), Desigan, Kumaran1 (AUTHOR), Lucas, M. Mercedes2 (AUTHOR), Mishra, Ankita3 (AUTHOR), Bowers, Robert M.4 (AUTHOR), Woyke, Tanja4 (AUTHOR), Epstein, Brendan5 (AUTHOR), Tiffin, Peter5 (AUTHOR), Pueyo, José J.2 (AUTHOR), Paape, Tim3,6 (AUTHOR) timothy.paape@usda.gov
Publikováno v: BMC Microbiology. 7/6/2024, Vol. 24 Issue 1, p1-23. 23p.
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7
Akademický článek
MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans.
Autor: Koch AW; Novartis Institutes for BioMedical Research, Cambridge, MA., Schiering N; Novartis Institutes for BioMedical Research, Basel, Switzerland., Melkko S; Novartis Institutes for BioMedical Research, Basel, Switzerland., Ewert S; Novartis Institutes for BioMedical Research, Basel, Switzerland., Salter J; Novartis Pharmaceuticals Corporation, East Hanover, NJ., Zhang Y; Novartis Pharmaceuticals Corporation, East Hanover, NJ., McCormack P; Novartis Pharma AG, Basel, Switzerland; and., Yu J; Novartis Institutes for BioMedical Research, Cambridge, MA., Huang X; Novartis Institutes for BioMedical Research, Cambridge, MA., Chiu YH; Novartis Institutes for BioMedical Research, Cambridge, MA., Chen Z; Novartis Institutes for BioMedical Research, Cambridge, MA., Schleeger S; Novartis Institutes for BioMedical Research, Basel, Switzerland., Horny G; Novartis Institutes for BioMedical Research, Basel, Switzerland., DiPetrillo K; Novartis Pharmaceuticals Corporation, East Hanover, NJ., Muller L; Novartis Institutes for BioMedical Research, Basel, Switzerland., Hein A; Novartis Institutes for BioMedical Research, Basel, Switzerland., Villard F; Novartis Institutes for BioMedical Research, Basel, Switzerland., Scharenberg M; Novartis Institutes for BioMedical Research, Basel, Switzerland., Ramage P; Novartis Institutes for BioMedical Research, Basel, Switzerland., Hassiepen U; Novartis Institutes for BioMedical Research, Basel, Switzerland., Côté S; Novartis Institutes for BioMedical Research, Basel, Switzerland., DeGagne J; Novartis Institutes for BioMedical Research, Basel, Switzerland., Krantz C; Novartis Institutes for BioMedical Research, Basel, Switzerland., Eder J; Novartis Institutes for BioMedical Research, Basel, Switzerland., Stoll B; Novartis Institutes for BioMedical Research, Cambridge, MA., Kulmatycki K; Novartis Institutes for BioMedical Research, Cambridge, MA., Feldman DL; Novartis Institutes for BioMedical Research, Cambridge, MA., Hoffmann P; Novartis Institutes for BioMedical Research, East Hanover, NJ., Basson CT; Novartis Institutes for BioMedical Research, Cambridge, MA., Frost RJA; Novartis Institutes for BioMedical Research, Basel, Switzerland., Khder Y; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Publikováno v: Blood [Blood] 2019 Mar 28; Vol. 133 (13), pp. 1507-1516. Date of Electronic Publication: 2019 Jan 28.
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8
Akademický článek
Challenges of Diphtheria Toxin Detection.
Autor: Prygiel, Marta1 (AUTHOR) mprygiel@pzh.gov.pl, Mosiej, Ewa1 (AUTHOR), Polak, Maciej1 (AUTHOR), Krysztopa-Grzybowska, Katarzyna1 (AUTHOR), Wdowiak, Karol1 (AUTHOR), Formińska, Kamila1 (AUTHOR), Zasada, Aleksandra A.1 (AUTHOR) azasada@pzh.gov.pl
Publikováno v: Toxins. Jun2024, Vol. 16 Issue 6, p245. 18p.
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9
Akademický článek
N -Heterocycles as Promising Antiviral Agents: A Comprehensive Overview.
Autor: Ahmad, Gulraiz1 (AUTHOR) gulchemist35@gmail.com, Sohail, Maria1 (AUTHOR) mariasohail899@gmail.com, Bilal, Muhammad2 (AUTHOR) muhammadbilalgcuf@gmail.com, Rasool, Nasir1 (AUTHOR) nasirrasool@gcuf.edu.pk, Qamar, Muhammad Usman3,4,5 (AUTHOR) musmanqamar@gcuf.edu.pk, Ciurea, Codrut6 (AUTHOR) marceanu@gmail.com, Marceanu, Luigi Geo6 (AUTHOR), Misarca, Catalin6 (AUTHOR)
Publikováno v: Molecules. May2024, Vol. 29 Issue 10, p2232. 67p.
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10
Akademický článek
The Inhibition of NS2B/NS3 Protease: A New Therapeutic Opportunity to Treat Dengue and Zika Virus Infection.
Autor: Starvaggi, Josè1 (AUTHOR) starvaggi4@gmail.com, Previti, Santo1 (AUTHOR), Zappalà, Maria1 (AUTHOR), Ettari, Roberta1 (AUTHOR) rettari@unime.it
Publikováno v: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 8, p4376. 22p.
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