Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma.

Autor: Maia-Silva D; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Cunniff PJ; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Schier AC; Department of Biochemistry, University of Colorado, Boulder, CO, USA., Skopelitis D; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Trousdell MC; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Moresco P; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Gao Y; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Kechejian V; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., He XY; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Sahin Y; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Wan L; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Alpsoy A; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Liverpool J; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Krainer AR; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Egeblad M; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Spector DL; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Fearon DT; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Dos Santos CO; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Taatjes DJ; Department of Biochemistry, University of Colorado, Boulder, CO, USA., Vakoc CR; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. vakoc@cshl.edu.

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Everything at once: cryo-EM yields remarkable insights into human RNA polymerase II transcription.

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An end-to-end workflow to study newly synthesized mRNA following rapid protein depletion in Saccharomyces cerevisiae.

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Filamentation and biofilm formation are regulated by the phase-separation capacity of network transcription factors in Candida albicans.

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