Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children.

Autor: Bastard P; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA.; Pediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP) , Paris, France., Gervais A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Taniguchi M; Dept. of Pediatrics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan., Saare L; Dept. of Pediatrics, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia., Särekannu K; Molecular Pathology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Le Voyer T; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Philippot Q; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Rosain J; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Bizien L; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Asano T; Dept. of Pediatrics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan., Garcia-Prat M; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB) , Barcelona, Spain., Parra-Martínez A; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB) , Barcelona, Spain., Migaud M; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Tsumura M; Dept. of Pediatrics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan., Conti F; Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna, Italy.; Dept. of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy., Belot A; National Reference Center for Rheumatic, and Autoimmune and Systemic Diseases in Children , Lyon, France.; Immunopathology Federation LIFE, Hospices Civils de Lyon , Lyon, France.; Hospices Civils de Lyon , Lyon, France.; International Center of Research in Infectiology, Lyon University, International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL , Lyon, France., Rivière JG; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB) , Barcelona, Spain., Morio T; Dept. of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Tanaka J; Dept. of Epidemiology, Infectious Disease Control and Prevention, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan., Javouhey E; Pediatric Intensive Care Unit, Hospices Civils de Lyon, Hopital Femme Mère Enfant , Lyon, France., Haerynck F; Dept. of Paediatric Immunology and Pulmonology, Center for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium., Duvlis S; Faculty of Medical Sciences, University 'Goce Delchev' , Stip, Republic of Northern Macedonia.; Institute of Public Health of the Republic of North Macedonia , Skopje, North Macedonia., Ozcelik T; Dept. of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey., Keles S; Meram Medical Faculty, Necmettin Erbakan University , Konya, Turkey., Tandjaoui-Lambiotte Y; Pulmonology and Infectious Disease Department, Saint Denis Hospital, Saint Denis, France.; INSERM UMR 1137 IAME, Paris, France.; INSERM UMR 1272 Hypoxia and Lung, Bobigny, France., Escoda S; Pediatric Dept., Saint-Denis Hospital, Saint-Denis, France., Husain M; Pediatric Dept., Saint-Denis Hospital, Saint-Denis, France., Pan-Hammarström Q; Division of Immunology, Dept. of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Hammarström L; Division of Immunology, Dept. of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Ahlijah G; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France., Abi Haidar A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France., Soudee C; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France., Arseguel V; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France., Abolhassani H; Division of Immunology, Dept. of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences , Tehran, Iran., Sahanic S; Dept. of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria., Tancevski I; Dept. of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria., Nukui Y; Dept. of Infection Control and Prevention, Medical Hospital, TMDU, Tokyo, Japan., Hayakawa S; Dept. of Pediatrics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan., Chrousos GP; University Research Institute of Maternal and Child Health and Precision Medicine, National and Kapodistrian University of Athens , Athens, Greece., Michos A; University Research Institute of Maternal and Child Health and Precision Medicine, National and Kapodistrian University of Athens , Athens, Greece.; First Dept. of Pediatics, National and Kapodistrian University of Athens, Athens, Greece., Tatsi EB; University Research Institute of Maternal and Child Health and Precision Medicine, National and Kapodistrian University of Athens , Athens, Greece.; First Dept. of Pediatics, National and Kapodistrian University of Athens, Athens, Greece., Filippatos F; University Research Institute of Maternal and Child Health and Precision Medicine, National and Kapodistrian University of Athens , Athens, Greece.; First Dept. of Pediatics, National and Kapodistrian University of Athens, Athens, Greece., Rodriguez-Palmero A; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat , Barcelona, Spain.; Dept. of Pediatrics, Germans Trias i Pujol University Hospital, UAB , Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER) , Madrid, Spain., Troya J; Dept. of Internal Medicine, Infanta Leonor University Hospital, Madrid, Spain., Tipu I; University of Management and Technology , Lahore, Pakistan., Meyts I; Dept. of Immunology, Laboratory of Inborn Errors of Immunity, Microbiology and Transplantation, KU Leuven, Leuven, Belgium.; Dept. of Pediatrics, Jeffrey Modell Diagnostic and Research Network Center, University Hospitals Leuven, Leuven, Belgium., Roussel L; Dept. of Medicine, Division of Infectious Diseases, McGill University Health Centre, Montréal, Canada.; Infectious Disease Susceptibility Program, Research Institute-McGill University Health Centre , Montréal, Canada., Ostrowski SR; Dept. of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Schidlowski L; Faculdades Pequeno Príncipe, Instituto de Pesquisa Pelé Pequeno Príncipe , Curitiba, Brazil., Prando C; Faculdades Pequeno Príncipe, Instituto de Pesquisa Pelé Pequeno Príncipe , Curitiba, Brazil., Condino-Neto A; Dept. of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Cheikh N; Pediatric Hematology Unit, University Hospital of Besançon , Besançon, France., Bousfiha AA; Dept. of Pediatric Infectious Disease and Clinical Immunology, CHU Ibn Rushd and LICIA, Laboratoire d'Immunologie Clinique, Inflammation et Allergie, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco., El Bakkouri J; Laboratory of Immunology, CHU Ibn Rushd and LICIA, Laboratoire d'Immunologie Clinique, Inflammation et Allergie, Faculty of Medicine and Pharmacy, Hassan II University , Casablanca, Morocco., Peterson P; Molecular Pathology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Pujol A; Neurometabolic Diseases Laboratory, IDIBELL-Hospital Duran i Reynals, CIBERER U759, and Catalan Institution of Research and Advanced Studies , Barcelona, Spain., Lévy R; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; Pediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP) , Paris, France., Quartier P; University Paris Cité, Imagine Institute , Paris, France.; Pediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP) , Paris, France., Vinh DC; Dept. of Medicine, Division of Infectious Diseases, McGill University Health Centre, Montréal, Canada.; Infectious Disease Susceptibility Program, Research Institute-McGill University Health Centre , Montréal, Canada., Boisson B; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Béziat V; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Zhang SY; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Borghesi A; Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo , Pavia, Italy., Pession A; Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna, Italy., Andreakos E; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens , Athens, Greece., Marr N; Research Branch, Sidra Medicine , Doha, Qatar., Mentis AA; University Research Institute of Maternal and Child Health and Precision Medicine, National and Kapodistrian University of Athens , Athens, Greece., Mogensen TH; Dept. of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark.; Dept. of Biomedicine, Aarhus University, Aarhus, Denmark., Rodríguez-Gallego C; Hospital Universitario de Gran Canaria Dr Negrín, Canarian Health System , Las Palmas, Spain.; Dept. of Clinical Sciences, University Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain.; Dept. of Medical and Surgical Sciences, School of Medicine, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain., Soler-Palacin P; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB) , Barcelona, Spain., Colobran R; Immunology Division, Genetics Dept., Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, UAB, Barcelona, Spain., Tillmann V; Dept. of Pediatrics, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia., Neven B; University Paris Cité, Imagine Institute , Paris, France.; Pediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP) , Paris, France., Trouillet-Assant S; Hospices Civils de Lyon , Lyon, France.; International Center of Research in Infectiology, Lyon University, International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL , Lyon, France.; Joint Research Unit, Hospices Civils de Lyon-bio Mérieux, Hospices Civils de Lyon, Lyon Sud Hospital , Pierre-Bénite, France.; International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL , Lyon, France., Brodin P; Unit for Clinical Pediatrics, Dept. of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.; Department of Immunology and Inflammation, Imperial College London, London, UK., Abel L; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Jouanguy E; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Zhang Q; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Martinón-Torres F; Translational Pediatrics and Infectious Diseases, Pediatrics Dept., Hospital Clínico Universitario de Santiago, Servizo Galego de Saude (SERGAS), Santiago de Compostela, Spain.; GENVIP Research Group, Instituto de Investigación Sanitaria de Santiago (IDIS), Universidad de Santiago de Compostela , Galicia, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III , Madrid, Spain., Salas A; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III , Madrid, Spain.; Facultade de Medicina, Unidade de Xenética, Instituto de Ciencias Forenses, Universidade de Santiago de Compostela, and GenPoB Research Group, IDIS, SERGAS , Galicia, Spain., Gómez-Carballa A; GENVIP Research Group, Instituto de Investigación Sanitaria de Santiago (IDIS), Universidad de Santiago de Compostela , Galicia, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III , Madrid, Spain.; Facultade de Medicina, Unidade de Xenética, Instituto de Ciencias Forenses, Universidade de Santiago de Compostela, and GenPoB Research Group, IDIS, SERGAS , Galicia, Spain., Gonzalez-Granado LI; Immunodeficiencies Unit, Hospital 12 de octubre, Research Institute Hospital 12 octubre , Madrid, Spain., Kisand K; Molecular Pathology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Okada S; Dept. of Pediatrics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan., Puel A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Cobat A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Casanova JL; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA.; Howard Hughes Medical Institute , New York, NY, USA.; Dept. of Pediatrics, Necker Hospital for Sick Children, AP-HP, Paris, France.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2024 Feb 05; Vol. 221 (2). Date of Electronic Publication: 2024 Jan 04.

Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia.

Autor: García-García A; Pediatric Allergy and Clinical Immunology Dept., Clinical Immunology and Primary Immunodeficiencies Unit, Hospital Sant Joan de Déu, Barcelona , Barcelona, Spain.; Study Group for Immune Dysfunction Diseases in Children, Institut de Recerca Sant Joan de Déu, Barcelona , Barcelona, Spain.; Clinical Immunology Unit, Hospital Sant Joan de Déu-Hospital Clínic Barcelona , Barcelona, Spain., Pérez de Diego R; Laboratory of Immunogenetics of Human Diseases, IdiPAZ Institute for Health Research, La Paz Hospital , Madrid, Spain., Flores C; Genomics Division, Instituto Tecnológico y de Energías Renovables , Santa Cruz de Tenerife, Spain.; Research Unit, Hospital Universitario N.S. de Candelaria , Santa Cruz de Tenerife, Spain.; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III , Madrid, Spain.; Dept. of Clinical Sciences, University Fernando Pessoa Canarias , Las Palmas de Gran Canaria, Spain., Rinchai D; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA., Solé-Violán J; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III , Madrid, Spain.; Dept. of Clinical Sciences, University Fernando Pessoa Canarias , Las Palmas de Gran Canaria, Spain.; Dept. of Intensive Care Medicine, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Deyà-Martínez À; Pediatric Allergy and Clinical Immunology Dept., Clinical Immunology and Primary Immunodeficiencies Unit, Hospital Sant Joan de Déu, Barcelona , Barcelona, Spain.; Study Group for Immune Dysfunction Diseases in Children, Institut de Recerca Sant Joan de Déu, Barcelona , Barcelona, Spain.; Clinical Immunology Unit, Hospital Sant Joan de Déu-Hospital Clínic Barcelona , Barcelona, Spain., García-Solis B; Laboratory of Immunogenetics of Human Diseases, IdiPAZ Institute for Health Research, La Paz Hospital , Madrid, Spain., Lorenzo-Salazar JM; Genomics Division, Instituto Tecnológico y de Energías Renovables , Santa Cruz de Tenerife, Spain., Hernández-Brito E; Dept. of Immunology, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Lanz AL; Dept. of Pediatrics, Division of Pediatric Immunology and Rheumatology, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität München , Munich, Germany., Moens L; Laboratory for Inborn Errors of Immunity, Dept. of Microbiology, Immunology and Transplantation KU Leuven , Leuven, Belgium., Bucciol G; Laboratory for Inborn Errors of Immunity, Dept. of Microbiology, Immunology and Transplantation KU Leuven , Leuven, Belgium.; Dept. of Pediatrics, Childhood Immunology, UZ Leuven , Leuven, Belgium., Almuqamam M; Dept. of Pediatrics, Drexel University College of Medicine, St Christopher's Hospital for Children , Philadelphia, PA, USA., Domachowske JB; Dept. of Pediatrics, SUNY Upstate Medical University , Syracuse, NY, USA., Colino E; Unidad de Enfermedades Infecciosas, Complejo Hospitalario Universitario Insular-Materno Infantil , Las Palmas de Gran Canaria, Spain., Santos-Perez JL; Unidad de Gestión Clínica de Pediatría y Cirugía Pediátrica, Hospital Virgen de las Nieves-IBS , Granada, Spain., Marco FM; Dept. of Immunology, Alicante University General Hospital Doctor Balmis , Alicante, Spain.; Alicante Institute for Health and Biomedical Research , Alicante, Spain., Pignata C; Dept. of Translational Medical Sciences, Section of Pediatrics, Federico II University , Naples, Italy., Bousfiha A; Dept. of Pediatric Infectious Diseases and Clinical Immunology, Ibn Rushd University Hospital , Casablanca, Morocco.; Clinical Immunology, Autoimmunity and Inflammation Laboratory, Faculty of Medicine and Pharmacy, Hassan II University , Casablanca, Morocco., Turvey SE; Dept. of Paediatrics, BC Children's Hospital, University of British Columbia , Vancouver, Canada., Bauer S; Clinic for Children and Adolescents. Dept. of Hematology and Oncology. University Clinic Erlangen , Erlangen, Germany., Haerynck F; Dept. of Pediatric Immunology and Pulmonology, Centre for Primary Immune Deficiency Ghent, Ghent University Hospital , Ghent, Belgium.; Dept. of Internal Medicine and Pediatrics, PID Research Laboratory, Ghent University , Ghent, Belgium., Ocejo-Vinyals JG; Dept. of Immunology, University Hospital Marqués de Valdecilla, IDIVAL , Santander, Spain., Lendinez F; Dept. of Pediatric Oncohematology, Hospital Materno Infantil Torrecárdenas , Almería, Spain., Prader S; Division of Immunology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland; University of Zurich , Zurich, Switzerland., Naumann-Bartsch N; Clinic for Children and Adolescents. Dept. of Hematology and Oncology. University Clinic Erlangen , Erlangen, Germany., Pachlopnik Schmid J; Division of Immunology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland; University of Zurich , Zurich, Switzerland., Biggs CM; Dept. of Paediatrics, BC Children's Hospital, University of British Columbia , Vancouver, Canada., Hildebrand K; Dept. of Paediatrics, BC Children's Hospital, University of British Columbia , Vancouver, Canada., Dreesman A; Dept. of Pediatrics, CHU St Pierre, ULB/VUB , Brussels, Belgium., Cárdenes MÁ; Dept. of Internal Medicine, Unit of Infectious Diseases, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Ailal F; Dept. of Pediatric Infectious Diseases and Clinical Immunology, Ibn Rushd University Hospital , Casablanca, Morocco.; Clinical Immunology, Autoimmunity and Inflammation Laboratory, Faculty of Medicine and Pharmacy, Hassan II University , Casablanca, Morocco., Benhsaien I; Dept. of Pediatric Infectious Diseases and Clinical Immunology, Ibn Rushd University Hospital , Casablanca, Morocco.; Clinical Immunology, Autoimmunity and Inflammation Laboratory, Faculty of Medicine and Pharmacy, Hassan II University , Casablanca, Morocco., Giardino G; Dept. of Translational Medical Sciences, Section of Pediatrics, Federico II University , Naples, Italy., Molina-Fuentes A; Dept. of Immunology, UGC Laboratories, University Hospital of Jaén , Jaén, Spain., Fortuny C; Study Group for Immune Dysfunction Diseases in Children, Institut de Recerca Sant Joan de Déu, Barcelona , Barcelona, Spain.; Pediatric Infectious Diseases Unit, Hospital Sant Joan de Déu , Barcelona, Spain.; CIBER of Epidemiology and Public Health, Madrid, Spain; Translational Research Network in Pediatric Infectious Diseases , Madrid, Spain.; Dept. of Surgery and Surgical Specializations, Facultat de Medicina i Ciències de la Salut, University of Barcelona , Barcelona, Spain., Madhavarapu S; Dept. of Pediatrics, Drexel University College of Medicine, St Christopher's Hospital for Children , Philadelphia, PA, USA., Conway DH; Dept. of Pediatrics, Drexel University College of Medicine, St Christopher's Hospital for Children , Philadelphia, PA, USA., Prando C; Instituto de Pesquisa Pelé Pequeno Príncipe, Faculdades Pequeno Príncipe, Hospital Pequeno Príncipe , Curitiba, Brazil., Schidlowski L; Instituto de Pesquisa Pelé Pequeno Príncipe, Faculdades Pequeno Príncipe, Hospital Pequeno Príncipe , Curitiba, Brazil., Martínez de Saavedra Álvarez MT; Dept. of Immunology, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Alfaro R; Dept. of Immunology, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Rodríguez de Castro F; Dept. of Medical and Surgical Sciences, School of Medicine, University of Las Palmas de Gran Canaria , Las Palmas de Gran Canaria, Spain.; Dept. of Respiratory Diseases, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Meyts I; Laboratory for Inborn Errors of Immunity, Dept. of Microbiology, Immunology and Transplantation KU Leuven , Leuven, Belgium.; Dept. of Pediatrics, Childhood Immunology, UZ Leuven , Leuven, Belgium., Hauck F; Dept. of Pediatrics, Division of Pediatric Immunology and Rheumatology, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität München , Munich, Germany., Puel A; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Bastard P; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; Pediatric Hematology and Immunology Unit, Department of Pediatrics, Necker Hospital for Sick Children, AP-HP , Paris, France., Boisson B; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Jouanguy E; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Abel L; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Cobat A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Zhang Q; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Casanova JL; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; Department of Pediatrics, Necker Hospital for Sick Children , Paris, France.; Howard Hughes Medical Institute , New York, NY, USA., Alsina L; Pediatric Allergy and Clinical Immunology Dept., Clinical Immunology and Primary Immunodeficiencies Unit, Hospital Sant Joan de Déu, Barcelona , Barcelona, Spain.; Study Group for Immune Dysfunction Diseases in Children, Institut de Recerca Sant Joan de Déu, Barcelona , Barcelona, Spain.; Clinical Immunology Unit, Hospital Sant Joan de Déu-Hospital Clínic Barcelona , Barcelona, Spain.; Dept. of Surgery and Surgical Specializations, Facultat de Medicina i Ciències de la Salut, University of Barcelona , Barcelona, Spain., Rodríguez-Gallego C; Dept. of Clinical Sciences, University Fernando Pessoa Canarias , Las Palmas de Gran Canaria, Spain.; Dept. of Immunology, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain.; Dept. of Medical and Surgical Sciences, School of Medicine, University of Las Palmas de Gran Canaria , Las Palmas de Gran Canaria, Spain.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2023 May 01; Vol. 220 (5). Date of Electronic Publication: 2023 Mar 03.

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Outcome of SARS-CoV-2 Infection in 121 Patients with Inborn Errors of Immunity: A Cross-Sectional Study.

Autor: Goudouris ES; IPPMG-Universidade Federal Do Rio de Janeiro (UFRJ), Rua Professor Luis Cantanhede, 77 ap 101, Rio de Janeiro, RJ, 22245-040, Brazil. egoudouris@gmail.com., Pinto-Mariz F; IPPMG-Universidade Federal Do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil., Mendonça LO; Clinica Croce and Center for Rare Diseases At 'Hospital 9 de Julho', Sao Paulo, SP, Brazil., Aranda CS; Universidade Federal de São Paulo (UNIFESP), Sao Paulo, SP, Brazil., Guimarães RR; Universidade Federal de São Paulo (UNIFESP), Sao Paulo, SP, Brazil., Kokron C; Division of Clinical Immunology and Allergy-Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (FMUSP), Sao Paulo, SP, Brazil., Barros MT; Division of Clinical Immunology and Allergy-Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (FMUSP), Sao Paulo, SP, Brazil., Anísio F; Instituto Fernandes Figueira (IFF-Fiocruz), Rio de Janeiro, RJ, Brazil., Alonso MLO; Serviço de Imunologia, Hospital Universitário Clementino Fraga Filho (HUCFF-UFRJ), Rio de Janeiro, RJ, Brazil., Marcelino F; Departamento de Alergia E Imunologia-Hospital Regional da Asa Norte (HRAN), Brasília, DF, Brazil., Valle SOR; Serviço de Imunologia, Hospital Universitário Clementino Fraga Filho (HUCFF-UFRJ), Rio de Janeiro, RJ, Brazil., Junior SD; Serviço de Imunologia, Hospital Universitário Clementino Fraga Filho (HUCFF-UFRJ), Rio de Janeiro, RJ, Brazil., Barreto IDP; Universidade Estadual Do Pará, Belem, PA, Brazil., Ferreira JFS; Hospital Infantil Albert Sabin/Universidade Estadual Do Ceará, Fortaleza, CE, Brazil., Roxo-Junior P; Serviço de Alergia E Imunologia Pediátrica Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (USP RP), Ribeirao Preto, SP, Brazil., do Rego Silva AM; Universidade Federal de Pernambuco, Recife, PE, Brazil., Campinhos FL; Asthma, Allergy and Immunology Reference Center, Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória, Vitoria, ES, Brazil., Bonfim C; Pediatric Bone Marrow Transplantation Unit, Hospital Pequeno Príncipe, Curitiba, PR, Brazil., Loth G; Pediatric Bone Marrow Transplantation Unit, Hospital de Clinicas, Universidade Federal do Parana, Curitiba, PR, Brazil., Fernandes JF; Instituto Do Tratamento Do Cancer Infantil Instituto da Criança, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (USP) and Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Garcia JL; Instituto Do Tratamento Do Cancer Infantil Instituto da Criança, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (USP) and Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Capelo A; Universidade Federal Do Estado Do Rio de Janeiro (UNIRIO), Rio de Janeiro, RJ, Brazil., Takano OA; Hospital Universitário Júlio Müller, Universidade Federal Do Mato Grosso (UFMT), Cuiaba, MT, Brazil., Nadaf MIV; Hospital Universitário Júlio Müller, Universidade Federal Do Mato Grosso (UFMT), Cuiaba, MT, Brazil., Toledo EC; Division of Allergy and Clinical Immunology, FAMERP, Faculdade de Medicina de São José Do Rio Preto , São José Do Rio Preto, SP, Brazil., Cunha LAO; Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil., Di Gesu RSW; Division of Allergy and Clinical Immunology, Department of Pediatrics, Hospital Criança Conceição, Porto Alegre, RS, Brazil., Schidlowski L; Faculdades Pequeno Príncipe, Instituto de Pesquisa Pelé Pequeno Príncipe, Curitiba, PR, Brasil., Fillipo P; Hospital Municipal Jesus, Rio de Janeiro, RJ, Brazil., Bichuetti-Silva DC; Universidade Federal de Goias (UFG), Goiânia, GO, Brazil., Soldateli G; Hospital Infantil Joana de Gusmão, Florianópolis, SC, Brazil., Ferraroni NR; Clínica Ferraroni, Brasília, DF, Brazil., de Oliveira Dantas E; Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil., Pestana S; Universidade Federal Fluminense (UFF), Rio de Janeiro, RJ, Brazil., Mansour E; Alergia E Imunologia, Departamento de Clínica Médica, Universidade de Campinas (UNICAMP), Campinas, SP, Brazil., Ulaf RG; Alergia E Imunologia, Departamento de Clínica Médica, Universidade de Campinas (UNICAMP), Campinas, SP, Brazil., Prando C; Hospital Pequeno Príncipe, Curitiba, Brazil.; Faculdades Pequeno Príncipe, Instituto de Pesquisa Pelé Pequeno Príncipe, Curitiba, PR, Brazil., Condino-Neto A; Department of Immunology, Institute of Biomedical Sciences, Universidade de Sao Paulo (USP), Sao Paulo, SP, Brazil., Grumach AS; Faculdade de Medicina, Centro Universitario Saude ABC, Santo Andre, SP, Brazil.

Publikováno v: Journal of clinical immunology [J Clin Immunol] 2021 Oct; Vol. 41 (7), pp. 1479-1489. Date of Electronic Publication: 2021 Jun 23.

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