Gradual in vitro Evolution of Cefepime Resistance in an ST131 Escherichia coli Strain Expressing a Plasmid-Encoded CMY-2 β-Lactamase

Autor: Donà, Valentina, Scheidegger, Maximilian, do Couto Pires, João Pedro, Furrer, Hansjakob, Atkinson, Andrew, Babouee Flury, Baharak

Publikováno v: Frontiers in Microbiology
Donà, Valentina; Scheidegger, Maximilian; do Couto Pires, João Pedro; Furrer, Hansjakob; Atkinson, Andrew; Babouee Flury, Baharak (2019). Gradual in vitro Evolution of Cefepime Resistance in an ST131 Escherichia coli Strain Expressing a Plasmid-Encoded CMY-2 β-Lactamase. Frontiers in Microbiology, 10, p. 1311. Frontiers 10.3389/fmicb.2019.01311

Background: In a previous report, a clinical ST131 Escherichia coli isolate (Ec-1),producing a plasmid-encoded AmpC β-lactamase CMY-2, evolved in vivo under cefepime (FEP) treatment to the FEP-resistant Ec-2 strain expressing an extended-spectrum β

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a367ad6d7654ca210e997c5db31cc7
http://europepmc.org/articles/PMC6581752