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Network medicine-based epistasis detection in complex diseases: ready for quantum computing.

Autor: Hoffmann M; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany.; Institute for Advanced Study (Lichtenbergstrasse 2 a, D-85748 Garching, Germany), Technical University of Munich, Germany.; National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, MD 20892, United States of America., Poschenrieder JM; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany.; Institute for Computational Systems Biology, University of Hamburg, Germany., Incudini M; Dipartimento di Informatica, Universit'a di Verona, Strada le Grazie 15 - 34137, Verona, Italy., Baier S; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany., Fitz A; Department of Health Technology, Section for Bioinformatics, Technical University of Denmark, DTU, 2800 Kgs. Lyngby, Denmark.; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Maier A; Institute for Computational Systems Biology, University of Hamburg, Germany., Hartung M; Institute for Computational Systems Biology, University of Hamburg, Germany., Hoffmann C; Institute for Computational Systems Biology, University of Hamburg, Germany., Trummer N; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany., Adamowicz K; Institute for Computational Systems Biology, University of Hamburg, Germany., Picciani M; Computational Mass Spectrometry, Technical University of Munich, Freising, Germany., Scheibling E; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany., Harl MV; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany., Lesch I; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany., Frey H; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany., Kayser S; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany., Wissenberg P; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany., Schwartz L; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany., Hafner L; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany.; Institute for Advanced Study (Lichtenbergstrasse 2 a, D-85748 Garching, Germany), Technical University of Munich, Germany., Acharya A; Division Data Science in Biomedicine, Peter L. Reichertz Institute for Medical Informatics, Technische Universität Braunschweig and Hannover Medical School, Rebenring 56, 38106 Braunschweig, Germany.; Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Rebenring 56, 38106 Braunschweig, Braunschweig, Germany., Hackl L; Institute for Computational Systems Biology, University of Hamburg, Germany., Grabert G; Division Data Science in Biomedicine, Peter L. Reichertz Institute for Medical Informatics, Technische Universität Braunschweig and Hannover Medical School, Rebenring 56, 38106 Braunschweig, Germany.; Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Rebenring 56, 38106 Braunschweig, Braunschweig, Germany., Lee SG; National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, MD 20892, United States of America.; School of Biological Sciences and Technology, Chonnam National University, Gwangju, Korea., Cho G; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju, Korea., Cloward M; Department of Biology, Brigham Young University, Provo, UT, USA., Jankowski J; National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, MD 20892, United States of America., Lee HK; National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, MD 20892, United States of America., Tsoy O; Institute for Computational Systems Biology, University of Hamburg, Germany., Wenke N; Institute for Computational Systems Biology, University of Hamburg, Germany., Pedersen AG; Department of Health Technology, Section for Bioinformatics, Technical University of Denmark, DTU, 2800 Kgs. Lyngby, Denmark., Bønnelykke K; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Mandarino A; International Centre for Theory of Quantum Technologies, University of Gdańsk, 80-309 Gdańsk, Poland., Melograna F; BIO3 - Systems Genetics; GIGA-R Medical Genomics, University of Liège, Liège, Belgium.; BIO3 - Systems Medicine; Department of Human Genetics, KU Leuven, Leuven, Belgium., Schulz L; Leibniz Supercomputing Centre of the Bavarian Academy of Sciences and Humanities (LRZ), Garching b. München, Germany., Climente-González H; RIKEN Center for Advanced Intelligence Project, Tokyo, Japan., Wilhelm M; Computational Mass Spectrometry, Technical University of Munich, Freising, Germany., Iapichino L; Leibniz Supercomputing Centre of the Bavarian Academy of Sciences and Humanities (LRZ), Garching b. München, Germany., Wienbrandt L; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Ellinghaus D; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Van Steen K; BIO3 - Systems Genetics; GIGA-R Medical Genomics, University of Liège, Liège, Belgium.; BIO3 - Systems Medicine; Department of Human Genetics, KU Leuven, Leuven, Belgium., Grossi M; European Organization for Nuclear Research (CERN), Geneva 1211, Switzerland., Furth PA; National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, MD 20892, United States of America.; Departments of Oncology & Medicine, Georgetown University, Washington, DC, USA., Hennighausen L; Institute for Advanced Study (Lichtenbergstrasse 2 a, D-85748 Garching, Germany), Technical University of Munich, Germany.; National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, MD 20892, United States of America., Di Pierro A; Dipartimento di Informatica, Universit'a di Verona, Strada le Grazie 15 - 34137, Verona, Italy., Baumbach J; Institute for Computational Systems Biology, University of Hamburg, Germany.; Computational BioMedicine Lab, University of Southern Denmark, Denmark., Kacprowski T; Division Data Science in Biomedicine, Peter L. Reichertz Institute for Medical Informatics, Technische Universität Braunschweig and Hannover Medical School, Rebenring 56, 38106 Braunschweig, Germany.; Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Rebenring 56, 38106 Braunschweig, Braunschweig, Germany., List M; Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Germany., Blumenthal DB; Department Artificial Intelligence in Biomedical Engineering (AIBE), Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Nov 09. Date of Electronic Publication: 2023 Nov 09.