Molecular determinants of treatment response in human germ cell tumors

Autor: Mayer, F., Stoop, H., Scheffer, G. L., Scheper, R., Oosterhuis, J. W., Leendert Looijenga, Bokemeyer, C.

Publikováno v: Clinical Cancer Research, 9(2), 767-773. American Association for Cancer Research Inc.
ResearcherID

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9c6e14d4d1d8c4fcd91eb1ae35c477ce
https://pure.eur.nl/en/publications/34764ea6-cdbd-44dc-93e0-3fd1c93e025d

Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues

Autor: Maliepaard, M., Scheffer, G. L., Faneyte, I. F., van Gastelen, M. A., Pijnenborg, A. C., Schinkel, A. H., van de Vijver, M. J., Scheper, R. J., Schellens, J. H.

Publikováno v: Cancer research, 61(8), 3458-3464. American Association for Cancer Research Inc.

High expression of the Breast Cancer Resistance Protein (BCRP) gene has been shown to be involved in resistance to chemotherapeutic drugs. Knowledge of the localization of BCRP protein in normal tissues may help unravel the normal function of this pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::f9cd433fc5c6dca6c33ad87f90e92788
https://pure.amc.nl/en/publications/subcellular-localization-and-distribution-of-the-breast-cancer-resistance-protein-transporter-in-normal-human-tissues(446e7463-0051-4c8c-a4b3-8896b666d1e5).html

Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies

Autor: Scheffer, G. L., Kool, M., Heijn, M., de Haas, M., Pijnenborg, A. C., Wijnholds, J., van Helvoort, A., de Jong, M. C., Hooijberg, J. H., Mol, C. A., van der Linden, M., de Vree, J. M., van der Valk, P., Elferink, R. P., Borst, P., Scheper, R. J.

Publikováno v: Cancer research, 60(18), 5269-5277. American Association for Cancer Research Inc.

Tumor cells may display a multidrug resistance phenotype by overexpression of ATP binding cassette transporter genes such as multidrug resistance (MDR) 1 P-glycoprotein (P-gp) or the multidrug resistance protein 1 (MRP1). MDR3 P-gp is a close homolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::56d93068f1362f6fc06373b42310ef1d
https://pure.amc.nl/en/publications/specific-detection-of-multidrug-resistance-proteins-mrp1-mrp2-mrp3-mrp5-and-mdr3-pglycoprotein-with-a-panel-of-monoclonal-antibodies(b03d6dd2-ec12-4b8d-bdd2-959868092af7).html

Drug resistance-associated marker Lrp for prediction of response to chemotherapy and prognoses in advanced ovarian carcinoma

Autor: Izquierdo, M A, van der Zee, A G, Vermorken, J B, van der Valk, P, Beliën, J A, Giaccone, G, Scheffer, G L, Flens, M J, Pinedo, H M, Kenemans, P

Publikováno v: Izquierdo, M A, van der Zee, A G, Vermorken, J B, van der Valk, P, Beliën, J A, Giaccone, G, Scheffer, G L, Flens, M J, Pinedo, H M & Kenemans, P 1995, ' Drug resistance-associated marker Lrp for prediction of response to chemotherapy and prognoses in advanced ovarian carcinoma ', Journal of the National Cancer Institute, vol. 87, no. 16, pp. 1230-7 .
Journal of the National Cancer Institute, 87(16), 1230-7. Oxford University Press

BACKGROUND: Drug resistance is a major impediment to the successful treatment of ovarian carcinoma. None of the earlier-identified resistance mechanisms, such as overexpression of the MDR1 gene product, P-glycoprotein (Pgp), has been shown to be a ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fed925567de6b64103c47a8205a518c1
https://research.vumc.nl/en/publications/8aaed43b-30e4-4f36-80ac-01a33d0482bd

Vascular colocalization of P-glycoprotein, multidrug-resistance associated protein 1, breast cancer resistance protein and major vault protein in human epileptogenic pathologies.

Autor: Sisodiya, S. M., Martinian, L., Scheffer, G. L., van der Valk, P., Scheper, R. J., Harding, B. N., Thom, M.

Publikováno v: Neuropathology & Applied Neurobiology; Feb2006, Vol. 32 Issue 1, p51-63, 13p, 5 Color Photographs, 5 Diagrams, 1 Chart