Recovery of 5-HT 1A receptors after irreversible blockade by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)

Autor: Bolaños-Jiménez, Francisco, Schechter, L E, Laporte, Anne Marie, Hamon, Michel, Gozlan, Henry

Publikováno v: Proceedings-Western Pharmacology Society
Proceedings-Western Pharmacology Society, [Western Pharmacology Society]; 1998, 1991, 34, pp.387-393
Proceedings-Western Pharmacology Society, 1991, 34, pp.387-393

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::26d8673fb9714681885c029e9e9e2b7d
https://hal.inrae.fr/hal-02708343

Alterations of central serotoninergic and dopaminergic neurotransmission in rats chronically treated with ipsapirone: biochemical and electrophysiological studies

Autor: Schechter, L E, Bolaños-Jiménez, Francisco, Gozlan, Henry, Lanfumey, L, Haj-Dahmane, S, Laporte, Anne Marie, Fattaccini, C M, Hamon, Michel

Publikováno v: Journal of Pharmacology and Experimental Therapeutics
Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 1990, 255 (3), pp.1335-1347
Journal of Pharmacology and Experimental Therapeutics, 1990, 255 (3), pp.1335-1347

International audience; Inasmuch as sustained treatment with the 5-hydroxytryptamine1A (5-HT1A) agonist, ipsapirone, is necessary for inducing anxiolytic and antidepressant effects in the clinic, investigations were performed for assessing the possib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d77c9eeca39327b14cfda90548551f71
https://hal.inrae.fr/hal-02711946

Preclinical characterization of WAY-211612: a dual 5-HT uptake inhibitor and 5-HT (1A) receptor antagonist and potential novel antidepressant.

Autor: Beyer, C. E., Lin, Q., Platt, B., Malberg, J., Hornby, G., Sullivan, K. M., Smith, D. L., Lock, T., Mitchell, P. J., Hatzenbuhler, N. T., Evrard, D. A., Harrison, B. L., Magolda, R., Pangalos, M. N., Schechter, L. E., Rosenzweig-Lipson, S., Andree, T. H.

Publikováno v: British Journal of Pharmacology; May2009, Vol. 157 Issue 2, p307-319, 13p, 5 Charts, 5 Graphs

Lecozotan (SRA-333): A Selective Serotonin 1A Receptor Antagonist That Enhances the Stimulated Release of Glutamate and Acetylcholine in the Hippocampus and Possesses Cognitive-Enhancing Properties.

Autor: Schechter, L E, Smith, D L, Rosenzweig-Lipson, S, Sukoff, S J, Dawson, L A, Marquis, K, Jones, D, Piesla, M, Andree, T, Nawoschik, S, Harder, J A, Womack, M D, Buccafusco, J, Terry, A V, Hoebel, B, Rada, P, Kelly, M, Abou-Gharbia, M, Barrett, J E, Childers, W

Publikováno v: The Journal of Pharmacology and Experimental Therapeutics; September 2005, Vol. 314 Issue: 3 p1274-89, 16p

Synthesis and Biological Evaluation of Benzodioxanylpiperazine Derivatives as Potent Serotonin 5-HT1A Antagonists:  The Discovery of Lecozotan

Autor: Childers, W. E., Jr., Abou-Gharbia, M. A., Kelly, M. G., Andree, T. H., Harrison, B. L., Ho, D. M., Hornby, G., Huryn, D. M., Potestio, L., Rosenzweig-Lipson, S. J., Schmid, J., Smith, D. L., Sukoff, S. J., Zhang, G., Schechter, L. E.

Publikováno v: Journal of Medicinal Chemistry; January 2005, Vol. 48 Issue: 10 p3467-3470, 4p