Toxicity Profile of eBAT, a Bispecific Ligand-Targeted Toxin Directed to EGFR and uPAR, in Mice and a Clinical Dog Model.

Autor: Dicovitsky RH; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Schappa JT; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Experimental Surgical Services, Department of Surgery, Medical School, University of Minnesota, Minneapolis, MN 55455, USA., Schulte AJ; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Lang HP; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Comparative Molecular Biosciences Graduate Program and DVM-PhD Dual Degree Program, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Kuerbitz E; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Roberts S; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., DePauw TA; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Microbiology, Immunology, and Cancer Biology Graduate Program, Medical School, University of Minnesota, Minneapolis, MN 55455, USA., Lewellen M; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Winter AL; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Stuebner K; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Buettner M; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Reid K; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Bergsrud K; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Pracht S; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Chehadeh A; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Feiock C; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., O'Sullivan MG; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Carlson T; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Armstrong AR; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Meritet D; Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA., Henson MS; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Weigel BJ; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, MN 55455, USA., Modiano JF; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Laboratory Medicine and Pathology, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.; Stem Cell Institute, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Engineering in Medicine, University of Minnesota, Minneapolis, MN 55455, USA., Borgatti A; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA., Vallera DA; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Radiation Oncology, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.

Publikováno v: Toxins [Toxins (Basel)] 2024 Aug 26; Vol. 16 (9). Date of Electronic Publication: 2024 Aug 26.

What is your diagnosis? Upper eyelid swelling in a dog.

Autor: Schappa JT; Veterinary Clinical Sciences Department, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA., Peterson A, Dubielzig RR, Lim CC, Overmann JA

Publikováno v: Veterinary clinical pathology [Vet Clin Pathol] 2014 Mar; Vol. 43 (1), pp. 111-2. Date of Electronic Publication: 2014 Jan 08.

Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed.

Autor: Tamburini BA; Integrated Department of Immunology, University of Colorado Denver, Denver, Colorado, USA., Trapp S, Phang TL, Schappa JT, Hunter LE, Modiano JF

Publikováno v: PloS one [PLoS One] 2009 May 20; Vol. 4 (5), pp. e5549. Date of Electronic Publication: 2009 May 20.