Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Schantel Williams"'
Autor:
Lisa Mosconi, Matilde Nerattini, Dawn C. Matthews, Steven Jett, Caroline Andy, Schantel Williams, Camila Boneu Yepez, Camila Zarate, Caroline Carlton, Francesca Fauci, Trisha Ajila, Silky Pahlajani, Randolph Andrews, Alberto Pupi, Douglas Ballon, James Kelly, Joseph R. Osborne, Sadek Nehmeh, Matthew Fink, Valentina Berti, Jonathan P. Dyke, Roberta Diaz Brinton
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract 17β-estradiol, the most biologically active estrogen, exerts wide-ranging effects in brain through its action on estrogen receptors (ERs), influencing higher-order cognitive function and neurobiological aging. However, our knowledge of ER e
Externí odkaz:
https://doaj.org/article/04b41408e446414b9a831dd8b790e68f
Autor:
Lisa Mosconi, Schantel Williams, Caroline Carlton, Camila Zarate, Camila Boneu, Francesca Fauci, Trisha Ajila, Matilde Nerattini, Steven Jett, Caroline Andy, Michael Battista, Silky Pahlajani, Joseph Osborne, Roberta Diaz Brinton, Jonathan P. Dyke
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Emerging evidence implicates chronic psychological stress as a risk factor for Alzheimer’s disease (AD). Herein, we examined the relationships between serum cortisol and multimodality brain AD biomarkers in 277 cognitively normal midlife i
Externí odkaz:
https://doaj.org/article/860ade4fa33e4745b368bbe7e2a3c650
Autor:
Caroline Andy, Matilde Nerattini, Steven Jett, Caroline Carlton, Camila Zarate, Camila Boneu, Francesca Fauci, Trisha Ajila, Michael Battista, Silky Pahlajani, Paul Christos, Matthew E. Fink, Schantel Williams, Roberta Diaz Brinton, Lisa Mosconi
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionDespite evidence from preclinical studies suggesting estrogen’s neuroprotective effects, the use of menopausal hormone therapy (MHT) to support cognitive function remains controversial.MethodsWe used random-effect meta-analysis and mult
Externí odkaz:
https://doaj.org/article/09c67cec818f437db119942f3f7e5e33
Autor:
Matilde Nerattini, Federica Rubino, Steven Jett, Caroline Andy, Camila Boneu, Camila Zarate, Caroline Carlton, Susan Loeb-Zeitlin, Yelena Havryliuk, Silky Pahlajani, Schantel Williams, Valentina Berti, Paul Christos, Matthew Fink, Jonathan P. Dyke, Roberta Diaz Brinton, Lisa Mosconi
Publikováno v:
Frontiers in Dementia, Vol 2 (2023)
IntroductionIn preclinical studies, menopausal elevations in pituitary gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), trigger Alzheimer's disease (AD) pathology and synaptic loss in female animals. Herein, we took a t
Externí odkaz:
https://doaj.org/article/f884dc760e994d1cb2aac216c5201547
Autor:
Matilde Nerattini, Steven Jett, Caroline Andy, Caroline Carlton, Camila Zarate, Camila Boneu, Michael Battista, Silky Pahlajani, Susan Loeb-Zeitlin, Yelena Havryulik, Schantel Williams, Paul Christos, Matthew Fink, Roberta Diaz Brinton, Lisa Mosconi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionDespite a large preclinical literature demonstrating neuroprotective effects of estrogen, use of menopausal hormone therapy (HT) for Alzheimer’s disease (AD) risk reduction has been controversial. Herein, we conducted a systematic revie
Externí odkaz:
https://doaj.org/article/9e78ef6e633442e78f1abd867fdff785
Autor:
Steven Jett, Camila Boneu, Camila Zarate, Caroline Carlton, Vibha Kodancha, Matilde Nerattini, Michael Battista, Silky Pahlajani, Schantel Williams, Jonathan P. Dyke, Lisa Mosconi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Many lines of evidence suggest that mitochondria have a central role in aging-related neurodegenerative diseases, such as Alzheimer's disease (AD). Mitochondrial dysfunction, cerebral energy dysmetabolism and oxidative damage increase with age, and a
Externí odkaz:
https://doaj.org/article/c8e0ba3f8adc4dbbab4e2afb7063b0f7
Autor:
Steven Jett, Jonathan P Dyke, Camila Boneu Yepez, Camila Zarate, Caroline Carlton, Eva Schelbaum, Grace Jang, Silky Pahlajani, Schantel Williams, Roberta Diaz Brinton, Lisa Mosconi
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281302 (2023)
Age, female sex, and APOE epsilon 4 (APOE4) genotype are the three greatest risk factors for late-onset Alzheimer's disease (AD). The convergence of these risks creates a hypometabolic AD-risk profile unique to women, which may help explain their hig
Externí odkaz:
https://doaj.org/article/991cdcb475d848998593ee61399fca79
Autor:
Anna Meyring-Wösten, Viktoriya Kuntsevich, Israel Campos, Schantel Williams, Jie Ma, Samir Patel, Chiarra Ornillo, Stephan Thijssen, Peter Kotanko
Publikováno v:
Kidney & Blood Pressure Research, Vol 42, Iss 2, Pp 314-326 (2017)
Background/Aims: In hemodialysis (HD) patients the endothelial and erythrocyte glycocalyx is impaired which in turn correlates with elevated erythrocyte sodium sensitivity (ESS). Additionally, apoptotic erythrocyte death (eryptosis), characterized by
Externí odkaz:
https://doaj.org/article/562682ae30004cbb8b4577f50fa932b9
Autor:
Lisa Mosconi, Steven Jett, Matilde Nerattini, Caroline Andy, Camila Boneu Yepez, Camila Zarate, Caroline Carlton, Vibha Kodancha, Eva Schelbaum, Schantel Williams, Silky Pahlajani, Susan Loeb-Zeitlin, Yelena Havryliuk, Randolph Andrews, Alberto Pupi, Douglas Ballon, James Kelly, Joseph Osborne, Sadek Nehmeh, Matthew Fink, Valentina Berti, Dawn Matthews, Jonathan Dyke, Roberta Diaz Brinton
17β-estradiol,the most biologically active estrogen, exerts wide-ranging effects in brain through its action on estrogen receptors (ERs), influencing higher-order cognitive function and neurobiological aging. However, our knowledge of ER expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1c6a28cf9ec693096cb04a35654a053
https://doi.org/10.21203/rs.3.rs-2573335/v1
https://doi.org/10.21203/rs.3.rs-2573335/v1
Autor:
Matilde Nerattini, Federica Rubino, Steven Jett, Caroline Andy, Camila Boneu Yepez, Camila Zarate, Caroline Carlton, Vibha Kodancha, Susan Loeb-Zeitlin, Yelena Havryliuk, Silky Pahlajani, Schantel Williams, Valentina Berti, Jonathan Dyke, Roberta Diaz Brinton, Lisa Mosconi
Menopause has been implicated in women’s greater life-time risk for Alzheimer’s disease (AD) due to its disruptive action on multiple neurobiological mechanisms resulting in amyloid-β deposition and synaptic dysfunction.While these effects are t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::509c90946e2dd23fdfd4d81d8cdf9d77
https://doi.org/10.21203/rs.3.rs-2351642/v1
https://doi.org/10.21203/rs.3.rs-2351642/v1