Library of Guidance for Health Scientists (LIGHTS): A new database for methods guidance in clinical research

Autor: Hirt, J, Ewald, H, Briel, M, Schandelmaier, S

Publikováno v: GMS Medizin-Bibliothek-Information; VOL: 22; DOC28 /20221220/

Methodological issues (e.g., ignoring missing data, irrelevant outcomes, flawed subgroup analyses) often limit the value of health research. One reason is that health researchers cannot easily find relevant methods guidance. To improve the findabilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1175::b892ca9ffe45524ec3621f367ef50357
http://www.egms.de/en/journals/mbi/2022-22/mbi000546.shtml

Development of the instrument to assess the credibility of effect modification analyses (ICEMAN) in randomized controlled trials and meta-analyses

Autor: Schandelmaier, S., Briel, M., Varadhan, R., Schmid, C.H., Devasenapathy, N., Hayward, R.A., Gagnier, J., Borenstein, M., van der Heijden, G.J.M.G., Dahabreh, I.J., Sun, X., Sauerbrei, W., Walsh, M., Ioannidis, J.P.A., Thabane, Lehana, Guyatt, G.H.

Publikováno v: CMAJ, 192(32), E901-E906. Canadian Medical Association
Schandelmaier, S, Briel, M, Varadhan, R, Schmid, C H, Devasenapathy, N, Hayward, R A, Gagnier, J, Borenstein, M, van der Heijden, G J M G, Dahabreh, I J, Sun, X, Sauerbrei, W, Walsh, M, Ioannidis, J P A, Thabane, L & Guyatt, G H 2020, ' Development of the instrument to assess the credibility of effect modification analyses (ICEMAN) in randomized controlled trials and meta-analyses ', CMAJ, vol. 192, no. 32, pp. E901-E906 . https://doi.org/10.1503/cmaj.200077

BACKGROUND: Most randomized controlled trials (RCTs) and meta-analyses of RCTs examine effect modification (also called a subgroup effect or interaction), in which the effect of an intervention varies by another variable (e.g., age or disease severit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f385ac8bdd2f4bf5e0f9a0ef74dfbec1
https://hdl.handle.net/1871.1/c2cedff5-b00f-44bb-a99d-3c2db9fdcf06

Use of GRADE for assessment of evidence about prognostic factors: rating certainty in identification of groups of patients with different absolute risks

Autor: Foroutan, F, Guyatt, G, Zuk, V, Vandvik, PO, Alba, AC, Mustafa, R, Vernooij, R, Rodriguez, I, Munn, Z, Roshanov, P, Riley, RD, Schandelmaier, S, Kujipers, T, Siemieniuk, R, Avbar, CC, Schunemann, H, Iorio, A

The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach to rating certainty in the results of research studies was initially developed for therapeutic questions. The approach considers: study design, risk of bias; inco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d683519236106feb147c7f4ff30fce24

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Discontinuation and Publication of Randomized Clinical Trials supported by the Main Public Funding Body in Switzerland: a Retrospective Cohort Study

Autor: Amstutz, A, Schandelmaier, S, von Niederhäusern, B, von Elm, E, Briel, M

Publikováno v: Klasse statt Masse-wider die wertlose Wissenschaft; 18. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin; 20170309-20170311; Hamburg; DOC17ebmV44 /20170223/

Background: The Swiss National Science Foundation (SNSF), the main public funding body for research in Switzerland, promotes academic excellence through competitive selection of study proposals and rigorous evaluation of feasibility. Completion statu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adeeb147d7be1c4b547d1a3db6c50db9