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Systemic antibodies administered by passive immunization prevent generalization of the infection by foot-and-mouth disease virus in cattle after oronasal challenge

Autor: Barrionuevo, Florencia, Di Giacomo, Sebastián, Bucafusco, Danilo, Ayude, Andrea, Schammas, Juan, Miraglia, M. Cruz, Capozzo, Alejandra, Borca, Manuel V., Perez-Filgueira, Mariano

Publikováno v: In Virology May 2018 518:143-151

Nanobodies against SARS-CoV-2 reduced virus load in the brain of challenged mice and neutralized Wuhan, Delta and Omicron Variants

Autor: Pavan, María Florencia, Bok, Marina, Juan, Rafael Betanzos San, Malito, Juan Pablo, Marcoppido, Gisela Ariana, Franco, Diego Rafael, Militello, Daniela Ayelen, Schammas, Juan Manuel, Bari, Sara, Stone, William B., López, Krisangel, Porier, Danielle L., Muller, John, Auguste, Albert J., Yuan, Lijuan, Wigdorovitz, Andrés, Parreño, Viviana, Ibañez, Lorena Itatí

Publikováno v: bioRxiv

In this work, we developed llama-derived nanobodies (Nbs) directed to the receptor binding domain (RBD) and other domains of the Spike (S) protein of SARS-CoV-2. Nanobodies were selected after the biopanning of two VHH-libraries, one of which was gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12cdc8ba616a81e1abae43319b7d1e21
https://europepmc.org/articles/PMC10054972/

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Assessment on different vaccine formulation parameters in the protection against heterologous challenge with FMDV in cattle

Autor: Sebastián Di Giacomo, Danilo Bucafusco, Juan Manuel Schammas, Juan Pega, María Cruz Miraglia, Florencia Barrionuevo, Alejandra Victoria Capozzo, Daniel Mariano Perez-Filgueira

Publikováno v: Viruses 14 (8) : 1781 (Agosto 2022)
INTA Digital (INTA)
Instituto Nacional de Tecnología Agropecuaria
instacron:INTA
Viruses; Volume 14; Issue 8; Pages: 1781

Foot-and-mouth disease (FMD) remains one of the major threats to animal health worldwide. Its causative agent, the FMD virus (FMDV), affects cloven-hoofed animals, including farm animals and wildlife species, inflicting severe damage to the internati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cad3e6f9ece1ecf4e5ecbe0e5da9168
https://www.mdpi.com/1999-4915/14/8/1781