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Autor:
Binas, Oliver, Jesus, Vanessa de, Landgraf, Tom, Völklein, Albrecht Eduard, Martins, Jason, Hymon, Daniel, Bains, Jasleen Kaur, Berg, Hannes, Biedenbänder, Thomas, Fürtig, Boris, Gande, Santosh Lakshmi, Niesteruk, Anna, Oxenfarth, Andreas, Qureshi, Nusrat, Schamber, Tatjana, Schnieders, Robbin, Tröster, Alix Friederike, Wacker, Anna, Wirmer-Bartoschek, Julia, Wirtz Martin, Maria Alexandra, Stirnal, Elke, Azzaoui, Kamal, Richter, Christian, Sreeramulu, Sridhar, Blommers, Marcel Jules José, Schwalbe, Harald
We report here the nuclear magnetic resonance 19F screening of 14 RNA targets with different secondary and tertiary structure to systematically assess the druggability of RNAs. Our RNA targets include representative bacterial riboswitches that natura
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https://explore.openaire.eu/search/publication?articleId=od_______603::b89d87171f4abff9aa96cf3dee3e0936
http://publikationen.ub.uni-frankfurt.de/files/63851/container.zip
http://publikationen.ub.uni-frankfurt.de/files/63851/container.zip
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Akademický článek
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Akademický článek
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Publikováno v:
ChemBioChem; 2/4/2022, Vol. 23 Issue 3, p1-9, 9p
Autor:
Binas, Oliver, Jesus, Vanessa, Landgraf, Tom, Völklein, Albrecht Eduard, Martins, Jason, Hymon, Daniel, Kaur Bains, Jasleen, Berg, Hannes, Biedenbänder, Thomas, Fürtig, Boris, Lakshmi Gande, Santosh, Niesteruk, Anna, Oxenfarth, Andreas, Shahin Qureshi, Nusrat, Schamber, Tatjana, Schnieders, Robbin, Tröster, Alix, Wacker, Anna, Wirmer‐Bartoschek, Julia, Wirtz Martin, Maria Alexandra
Publikováno v:
ChemBioChem; 1/15/2021, Vol. 22 Issue 2, p423-433, 11p
Akademický článek
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Autor:
Wacker A; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Weigand JE; Department of Biology, Technical University of Darmstadt, Schnittspahnstrasse 10, 64287 Darmstadt, Germany., Akabayov SR; Faculty of Chemistry, Weizmann Institute of Science, 7610001 Rehovot, Israel., Altincekic N; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Bains JK; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Banijamali E; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Biomedicum 9B, Solnavägen 9, 17177 Stockholm, Sweden., Binas O; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Castillo-Martinez J; School of Medicine, Catholic University of Valencia, C/Quevedo 2, 46001 Valencia, Spain., Cetiner E; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Ceylan B; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Chiu LY; Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA., Davila-Calderon J; Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA., Dhamotharan K; Institute for Molecular Biosciences., Duchardt-Ferner E; Institute for Molecular Biosciences., Ferner J; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Frydman L; Faculty of Chemistry, Weizmann Institute of Science, 7610001 Rehovot, Israel., Fürtig B; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Gallego J; School of Medicine, Catholic University of Valencia, C/Quevedo 2, 46001 Valencia, Spain., Grün JT; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Hacker C; Signals GmbH & Co. KG, Graf-von-Stauffenberg-Allee 83, 60438 Frankfurt/M, Germany., Haddad C; Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA., Hähnke M; Signals GmbH & Co. KG, Graf-von-Stauffenberg-Allee 83, 60438 Frankfurt/M, Germany., Hengesbach M; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Hiller F; Signals GmbH & Co. KG, Graf-von-Stauffenberg-Allee 83, 60438 Frankfurt/M, Germany., Hohmann KF; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Hymon D; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., de Jesus V; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Jonker H; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Keller H; Institute for Molecular Biosciences., Knezic B; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Landgraf T; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Löhr F; Institute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Luo L; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Biomedicum 9B, Solnavägen 9, 17177 Stockholm, Sweden., Mertinkus KR; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Muhs C; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Novakovic M; Faculty of Chemistry, Weizmann Institute of Science, 7610001 Rehovot, Israel., Oxenfarth A; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Palomino-Schätzlein M; School of Medicine, Catholic University of Valencia, C/Quevedo 2, 46001 Valencia, Spain., Petzold K; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Biomedicum 9B, Solnavägen 9, 17177 Stockholm, Sweden., Peter SA; Department of Biology, Technical University of Darmstadt, Schnittspahnstrasse 10, 64287 Darmstadt, Germany., Pyper DJ; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Qureshi NS; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Riad M; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Biomedicum 9B, Solnavägen 9, 17177 Stockholm, Sweden., Richter C; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Saxena K; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Schamber T; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Scherf T; Faculty of Chemistry, Weizmann Institute of Science, 7610001 Rehovot, Israel., Schlagnitweit J; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Biomedicum 9B, Solnavägen 9, 17177 Stockholm, Sweden., Schlundt A; Institute for Molecular Biosciences., Schnieders R; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Schwalbe H; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Simba-Lahuasi A; School of Medicine, Catholic University of Valencia, C/Quevedo 2, 46001 Valencia, Spain., Sreeramulu S; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Stirnal E; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Sudakov A; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Tants JN; Institute for Molecular Biosciences., Tolbert BS; Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA., Vögele J; Institute for Molecular Biosciences., Weiß L; Institute for Molecular Biosciences., Wirmer-Bartoschek J; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Wirtz Martin MA; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany., Wöhnert J; Institute for Molecular Biosciences., Zetzsche H; Institute for Organic Chemistry and Chemical Biology, Max-von-Laue-Strasse 7, 60438 Frankfurt/M., Germany.
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2021 Jul 09; Vol. 49 (12), pp. 7204-7205.
Autor:
Binas O; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., de Jesus V; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Landgraf T; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Völklein AE; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Martins J; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Hymon D; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Kaur Bains J; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Berg H; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Biedenbänder T; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Fürtig B; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Lakshmi Gande S; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Niesteruk A; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Oxenfarth A; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Shahin Qureshi N; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Schamber T; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Schnieders R; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Tröster A; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Wacker A; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Wirmer-Bartoschek J; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Wirtz Martin MA; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Stirnal E; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Azzaoui K; Saverna Therapeutics, Gewerbestrasse 24, 4123, Allschwil, Switzerland., Richter C; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., Sreeramulu S; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany., José Blommers MJ; Saverna Therapeutics, Gewerbestrasse 24, 4123, Allschwil, Switzerland., Schwalbe H; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt am Main, Germany.
Publikováno v:
Chembiochem : a European journal of chemical biology [Chembiochem] 2021 Jan 15; Vol. 22 (2), pp. 423-433. Date of Electronic Publication: 2020 Sep 25.