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Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.

Autor: Hoshino A; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan; Japan Science and Technology Agency, PRESTO, Tokyo, Japan. Electronic address: ayukohoshino@bio.titech.ac.jp., Kim HS; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Yonsei Cancer Center, Division of Medical Oncology, Department of Internal Medicine, Brain Korea 21 Plus Project for Medical Sciences, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea., Bojmar L; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Rudbeck Laboratory, Uppsala, Sweden., Gyan KE; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Tri-Institutional PhD Program in Computational Biology and Medicine, New York, NY, USA., Cioffi M; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Hernandez J; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Surgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD USA., Zambirinis CP; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rodrigues G; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Graduate Program in Areas of Basic and Applied Biology, Abel Salazar Biomedical Sciences Institute, University of Porto, Porto, Portugal., Molina H; Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Heissel S; Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Mark MT; Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Steiner L; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland., Benito-Martin A; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Lucotti S; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Di Giannatale A; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Department of Pediatric Haematology/Oncology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Offer K; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Nakajima M; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Williams C; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Nogués L; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Microenvironment and Metastasis Laboratory, Department of Molecular Oncology, Spanish National Cancer Research Center (CNIO), Madrid, Spain., Pelissier Vatter FA; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Hashimoto A; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo, Tokyo, Japan., Davies AE; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA., Freitas D; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; i3S-Institute for Research and Innovation in Health, University of Porto, Rua Alfredo Allen 208, Porto, Portugal., Kenific CM; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Ararso Y; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Buehring W; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Lauritzen P; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Ogitani Y; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Sugiura K; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Takahashi N; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan., Alečković M; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Bailey KA; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Jolissant JS; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wang H; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Harris A; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Schaeffer LM; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., García-Santos G; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Department of General and Gastrointestinal Surgery, Hospital Universitario Central de Asturias (HUCA), Oviedo, Spain., Posner Z; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Balachandran VP; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Khakoo Y; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Raju GP; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Scherz A; Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel., Sagi I; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel., Scherz-Shouval R; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Yarden Y; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel., Oren M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Malladi M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Petriccione M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., De Braganca KC; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Donzelli M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fischer C; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vitolano S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wright GP; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ganshaw L; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Marrano M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ahmed A; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., DeStefano J; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Danzer E; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Pediatric Surgical Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Roehrl MHA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lacayo NJ; Lucile Packard Children's Hospital Stanford, Stanford, CA, USA., Vincent TC; Department of Immunology, Genetics and Pathology, Uppsala University, Rudbeck Laboratory, Uppsala, Sweden; Department of Microbiology, New York University School of Medicine, New York, NY, USA., Weiser MR; Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Brady MS; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Meyers PA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wexler LH; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ambati SR; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chou AJ; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Slotkin EK; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Modak S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Roberts SS; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Basu EM; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Diolaiti D; Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA., Krantz BA; Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cardoso F; Breast Unit, Champalimaud Clinical Center/Champalimaud Foundation, Lisbon, Portugal., Simpson AL; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Berger M; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rudin CM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Simeone DM; Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA., Jain M; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA., Ghajar CM; Public Health Sciences Division/Translational Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Batra SK; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA., Stanger BZ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Bui J; Department of Pathology, University of California San Diego, La Jolla, CA, USA., Brown KA; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Rajasekhar VK; Orthopedic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Healey JH; Orthopedic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., de Sousa M; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Graduate Program in Areas of Basic and Applied Biology, Abel Salazar Biomedical Sciences Institute, University of Porto, Porto, Portugal., Kramer K; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sheth S; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA., Baisch J; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA; Drukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA., Pascual V; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA; Drukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA., Heaton TE; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Pediatric Surgical Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., La Quaglia MP; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Pediatric Surgical Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pisapia DJ; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Schwartz R; Division of Gastroenterology & Hepatology, Weill Cornell Medicine, New York, NY, USA., Zhang H; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Liu Y; Thoracic Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Shukla A; Department of Pathology and Laboratory Medicine, University of Vermont, Burlington, VT, USA., Blavier L; Department of Pediatrics and Biochemistry and Molecular Medicine, University of Southern California, CA, USA., DeClerck YA; Department of Pediatrics and Biochemistry and Molecular Medicine, University of Southern California, CA, USA., LaBarge M; Department of Population Sciences, Beckman Research Institute at City of Hope, Duarte, CA, USA., Bissell MJ; Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Caffrey TC; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA., Grandgenett PM; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA., Hollingsworth MA; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA., Bromberg J; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Costa-Silva B; Champalimaud Research, Champalimaud Foundation, Lisbon, Portugal., Peinado H; Microenvironment and Metastasis Laboratory, Department of Molecular Oncology, Spanish National Cancer Research Center (CNIO), Madrid, Spain., Kang Y; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Garcia BA; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., O'Reilly EM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kelsen D; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Trippett TM; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Jones DR; Thoracic Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Matei IR; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Jarnagin WR; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: jarnagiw@mskcc.org., Lyden D; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. Electronic address: dcl2001@med.cornell.edu.

Publikováno v: Cell [Cell] 2020 Aug 20; Vol. 182 (4), pp. 1044-1061.e18. Date of Electronic Publication: 2020 Aug 13.

Induction of Aggregatibacter actinomycetemcomitans leukotoxin expression by IS1301 and orfA.

Autor: Schaeffer LM; Department of Periodontics, Endodontics and Dental Hygiene, University of Louisville School of Dentistry, Louisville, KY 40292, USA., Schmidt ML; Department of Periodontics, Endodontics and Dental Hygiene, University of Louisville School of Dentistry, Louisville, KY 40292, USA., Demuth DR; Department of Periodontics, Endodontics and Dental Hygiene, University of Louisville School of Dentistry, Louisville, KY 40292, USA.

Publikováno v: Microbiology (Reading, England) [Microbiology (Reading)] 2008 Feb; Vol. 154 (Pt 2), pp. 528-538.