Zobrazeno 1 - 10
of 656
pro vyhledávání: '"Schönhuth, A."'
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-39 (2023)
Abstract Although generally superior, hybrid approaches for correcting errors in third-generation sequencing (TGS) reads, using next-generation sequencing (NGS) reads, mistake haplotype-specific variants for errors in polyploid and mixed samples. We
Externí odkaz:
https://doaj.org/article/47194e0171254924a28b9d916ac34a61
Autor:
Ray, Sumanta, Lall, Snehalika, Mukhopadhyay, Anirban, Bandyopadhyay, Sanghamitra, Schönhuth, Alexander
Coronavirus Disease 2019 (COVID-19) has been creating a worldwide pandemic situation. Repurposing drugs, already shown to be free of harmful side effects, for the treatment of COVID-19 patients is an important option in launching novel therapeutic st
Externí odkaz:
http://arxiv.org/abs/2007.02338
Autor:
Balvert, Marleen, Patoulidis, Georgios, Patti, Andrew, Deist, Timo M., Eyler, Christine, Dutilh, Bas E., Schönhuth, Alexander, Craft, David
Personalizing drug prescriptions in cancer care based on genomic information requires associating genomic markers with treatment effects. This is an unsolved challenge requiring genomic patient data in yet unavailable volumes as well as appropriate q
Externí odkaz:
http://arxiv.org/abs/1912.11548
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Consensus sequence-based methods for self-correction of long-read sequencing data are affected by biases that can mask true variants characterizing little-covered or low-frequency haplotypes. Here, to address this issue, the authors develop a variati
Externí odkaz:
https://doaj.org/article/ea44329a9c644c6c8343ca1ab910ac12
Akademický článek
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The folding structure of the DNA molecule combined with helper molecules, also referred to as the chromatin, is highly relevant for the functional properties of DNA. The chromatin structure is largely determined by the underlying primary DNA sequence
Externí odkaz:
http://arxiv.org/abs/1806.04931
Autor:
Chikhi, Rayan, Schönhuth, Alexander
A characterization of the tree $T^*$ such that $\mathrm{BP}(T^*)=\overleftrightarrow{\mathrm{DFUDS}(T)}$, the reversal of $\mathrm{DFUDS}(T)$ is given. An immediate consequence is a rigorous characterization of the tree $\hat{T}$ such that $\mathrm{B
Externí odkaz:
http://arxiv.org/abs/1804.04263
Autor:
Ray, Sumanta, Lall, Snehalika, Mukhopadhyay, Anirban, Bandyopadhyay, Sanghamitra, Schönhuth, Alexander
Publikováno v:
In Artificial Intelligence In Medicine December 2022 134
Publikováno v:
Nature Communications; 10/7/2024, Vol. 15 Issue 1, p1-17, 17p
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-27 (2022)
Abstract Haplotype-resolved de novo assembly of highly diverse virus genomes is critical in prevention, control and treatment of viral diseases. Current methods either can handle only relatively accurate short read data, or collapse haplotype-specifi
Externí odkaz:
https://doaj.org/article/fdea4fa32a77478d8403b766d81f8b28