A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile.

Autor: Adak S; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Ye N; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Calderone LA; Department of Biochemistry, Brandeis University, Waltham, MA, USA., Duan M; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA., Lubeck W; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Schäfer RJB; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Lukowski AL; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Houk KN; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA., Pandelia ME; Department of Biochemistry, Brandeis University, Waltham, MA, USA. mepandelia@brandeis.edu., Drennan CL; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA. cdrennan@mit.edu.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. cdrennan@mit.edu.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA. cdrennan@mit.edu., Moore BS; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA. bsmoore@ucsd.edu.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, CA, USA. bsmoore@ucsd.edu.

Publikováno v: Nature chemistry [Nat Chem] 2024 Dec; Vol. 16 (12), pp. 1989-1998. Date of Electronic Publication: 2024 Sep 16.

Catalytic templated length-controlled oligomerization.

Autor: Lewandowski B; Laboratory of Organic Chemistry, D-CHAB, ETH Zurich, Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland. Bartosz.Lewandowski@org.chem.ethz.ch., Schäfer RJB; Laboratory of Organic Chemistry, D-CHAB, ETH Zurich, Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland. Bartosz.Lewandowski@org.chem.ethz.ch., Cotter E; Laboratory of Organic Chemistry, D-CHAB, ETH Zurich, Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland. Bartosz.Lewandowski@org.chem.ethz.ch., Harangozo D; Laboratory of Organic Chemistry, D-CHAB, ETH Zurich, Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland. Bartosz.Lewandowski@org.chem.ethz.ch., Wennemers H; Laboratory of Organic Chemistry, D-CHAB, ETH Zurich, Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland. Bartosz.Lewandowski@org.chem.ethz.ch.

Publikováno v: Faraday discussions [Faraday Discuss] 2023 Aug 11; Vol. 244 (0), pp. 119-133. Date of Electronic Publication: 2023 Aug 11.

Terpene biosynthesis in marine sponge animals.

Autor: Wilson K; Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093., de Rond T; Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.; School of Chemical Sciences, University of Auckland, Auckland 1142, New Zealand., Burkhardt I; Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093., Steele TS; Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.; Department of Chemistry & Biochemistry, University of California, San Diego, La Jolla, CA 92093., Schäfer RJB; Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093., Podell S; Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093., Allen EE; Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093., Moore BS; Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Feb 28; Vol. 120 (9), pp. e2220934120. Date of Electronic Publication: 2023 Feb 21.

From Tryptophan to Toxin: Nature's Convergent Biosynthetic Strategy to Aetokthonotoxin.

Autor: Adak S; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093, United States., Lukowski AL; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093, United States., Schäfer RJB; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093, United States., Moore BS; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093, United States.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, California 92093, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2022 Feb 23; Vol. 144 (7), pp. 2861-2866. Date of Electronic Publication: 2022 Feb 10.

Recent Advances in Bioorthogonal Reactions.

Autor: Schäfer RJB; Laboratorium für Organische Chemie, ETH Zurich, D-CHAB, Vladimir-Prelog-Weg 3, CH-8093 Zürich, SCS-DSM Award for best poster presentation in Chemical Biology., Aronoff MR; Laboratorium für Organische Chemie, ETH Zurich, D-CHAB, Vladimir-Prelog-Weg 3, CH-8093 Zürich., Wennemers H; Laboratorium für Organische Chemie, ETH Zurich, D-CHAB, Vladimir-Prelog-Weg 3, CH-8093 Zürich;, Email: helma.wennemers@org.chem.ethz.ch.

Publikováno v: Chimia [Chimia (Aarau)] 2019 Apr 24; Vol. 73 (4), pp. 308-312.