Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Scasnár"'
Autor:
Bezek, Š., Šortés, L., Ščasnár, V., Bauerová, K., Kállay, Z., Ďurišová, M., Mihalová, D., Bohov, P., Faberová, V., Kukan, M., Trnovec, T., Koprda, V.
Publikováno v:
In Life Sciences 1999 65(18):2003-2005
Publikováno v:
Radiation and Environmental Biophysics. 30:277-287
The heads of rats were irradiated by 4 MeV electrons in doses 90, 180, and 360 Gy. The observed times of deaths ranged 120-600, 60-420, and 150-370 min after 90, 180, and 360 Gy, respectively. A dose dependent decrease of the brain uptake index of ha
Publikováno v:
Experientia. 46:1017-1020
The passage of 6 model drugs; acetylsalicylic acid, chloramphenicol, ethimizol, carbisocaine, heptacaine, and diazepam, through the blood-brain barrier, was determined in unirradiated control rats and in animals 1, 3, and 7 days after irradiation of
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 18(2)
Distribution of 14C-bendamustine following intravenous (i.v.) administration to mice was examined by whole body autoradiographic (WBAR) and quantitative techniques. The WBAR study showed that 14C-bendamustine-derived radioactivity was distributed ext
Publikováno v:
Die Pharmazie. 46(11)
Biliary excretion of bendamustin (Cytostasan, 5-[bis(2-chloroethyl)amino]-i-methylbenzimidazole-2-butyric acid; 1) and its metabolites was studied in rats after i.v. administration of 14C-1. The most significant finding was the rapid excretion of 1 r
Publikováno v:
Ceskoslovenska farmacie. 39(2)
On day 29 of gravidity, the New Zealand white breed rabbits were intravenously administered 3H-pentacaine (0.5 mg.kg-1), a new local anaesthetic agent with anti-ulcerous effect in order to study the distribution in pregnant females. Transplacental pa
Publikováno v:
Arzneimittel-Forschung. 37(7)
Pharmacokinetics of a local anaesthetic of the carbanilate type (Heptacaine; in the following briefly called HCP), was studied using a labelled product, N-[2-(2-[1-14C]-heptyloxyphenylcarbamoyloxy)ethyl]piperidinum++ + chloride. Determination of HCP
Publikováno v:
Bratislavske lekarske listy. 69(3)
Publikováno v:
Die Pharmazie. 43(3)
In this study the stability of 14C-Cytostasan (1, bendamustine), in water solutions was investigated. In distilled water a rapid degradation of carrier-free 14C-1 occurred. The degradation products of 14C-1 are 14C-monohydroxy-1 and 14C-dihydroxy-1 (
Publikováno v:
Die Pharmazie. 40(4)