Genetic ablation of the isoform γ of PI3K decreases antidepressant efficacy of ketamine in male mice.

Autor: Vaz GN; Department of Pharmacology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Turcato FC; Department of Neurological Surgery, Case Western Reserve University, Cleveland, USA., Lima IAV; Department of Pharmacology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Scarante FF; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Araújo MR; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Brigante TAV; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Rodrigues LCM; Department of Physiological Sciences, Health Science Center, Universidade Federal do Espírito Santo, Vitória, Brazil., Guimarães FS; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Hallak JEC; Department of Neuroscience and Behavior, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., Crippa JA; Department of Neuroscience and Behavior, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., Teixeira AL; Faculdade Santa Casa BH, Belo Horizonte, Brazil & Neuropsychiatry Program, Department of Psychiatry & Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77054, USA., de Oliveira ACP; Department of Pharmacology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Campos AC; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

Publikováno v: IBRO neuroscience reports [IBRO Neurosci Rep] 2024 Jun 11; Vol. 17, pp. 87-95. Date of Electronic Publication: 2024 Jun 11 (Print Publication: 2024).

The chronic pharmacological antagonism of the CB 1 receptor is not involved in the behavioral effects of antidepressants administered in mice submitted to chronic unpredictable stress.

Autor: Ribeiro MA; Department of Pharmacology and Therapeutics, State University of Maringá, 5790 Colombo Ave, Maringá, Paraná, Brazil., Aguiar RP; Department of Pharmacology and Therapeutics, State University of Maringá, 5790 Colombo Ave, Maringá, Paraná, Brazil., Scarante FF; Department of Pharmacology and Therapeutics, State University of Maringá, 5790 Colombo Ave, Maringá, Paraná, Brazil., Fusse EJ; Mental Health Graduate Program, Ribeirão Preto Medical School, University of São Paulo, 2650 Tenente Catão Roxo Ave, Ribeirão Preto, São Paulo, Brazil., de Oliveira RMW; Department of Pharmacology and Therapeutics, State University of Maringá, 5790 Colombo Ave, Maringá, Paraná, Brazil., Guimarães FS; Department of Pharmacology and Therapeutics, State University of Maringá, 5790 Colombo Ave, Maringá, Paraná, Brazil., Campos AC; Department of Pharmacology and Therapeutics, State University of Maringá, 5790 Colombo Ave, Maringá, Paraná, Brazil. Electronic address: allinecampos@usp.br.

Publikováno v: Behavioural brain research [Behav Brain Res] 2023 Jul 26; Vol. 450, pp. 114502. Date of Electronic Publication: 2023 May 19.

Enhanced proliferation of oligodendrocyte progenitor cells following retrovirus mediated Achaete-scute complex-like 1 overexpression in the postnatal cerebral cortex in vivo .

Autor: Galante C; Institute of Physiological Chemistry, University Medical Center Johannes Gutenberg University, Mainz, Germany., Marichal N; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom., Scarante FF; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil., Ghayad LM; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom., Shi Y; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.; The Francis Crick Institute, London, United Kingdom., Schuurmans C; Biological Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Berninger B; Institute of Physiological Chemistry, University Medical Center Johannes Gutenberg University, Mainz, Germany.; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.; The Francis Crick Institute, London, United Kingdom.; MRC Centre for Neurodevelopmental Disorders, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.; Focus Program Translational Neuroscience, Johannes Gutenberg University, Mainz, Germany., Péron S; Institute of Physiological Chemistry, University Medical Center Johannes Gutenberg University, Mainz, Germany.; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Publikováno v: Frontiers in neuroscience [Front Neurosci] 2022 Dec 02; Vol. 16, pp. 919462. Date of Electronic Publication: 2022 Dec 02 (Print Publication: 2022).

Cannabidiol for COVID-19 Patients with Mild to Moderate Symptoms (CANDIDATE Study): A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Autor: Crippa JAS; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil., Pacheco JC; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Zuardi AW; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil., Guimarães FS; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil.; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Campos AC; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Osório FL; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil., Loureiro SR; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Dos Santos RG; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil., Souza JDS; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Ushirohira JM; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Ferreira RR; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Mancini Costa KC; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Scomparin DS; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Scarante FF; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Pires-Dos-Santos I; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Mechoulam R; Department of Medicinal Chemistry and Natural Products, The Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, Israel., Kapczinski F; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil.; Department of Psychiatry and Behavioural Neurosciences, McMaster University and St. Joseph's Healthcare Hamilton, Hamilton, Canada.; Graduate Program in Psychiatry and Behavioral Sciences, Department of Psychiatry, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil., Fonseca BAL; Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Esposito DLA; Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Passos ADC; Department of Social Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Dal Fabbro AL; Department of Social Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Bellissimo-Rodrigues F; Department of Social Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Arruda E; Department of Cell and Molecular Biology, and Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Scarpelini S; Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Andraus MH; Chromatox Laboratory Ltda., São Paulo, Brazil., Nather Junior JC; Department of Medical Imaging, Hematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Wada DT; Department of Medical Imaging, Hematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Koenigkam-Santos M; Department of Medical Imaging, Hematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Santos AC; Department of Medical Imaging, Hematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Busatto Filho G; Laboratory of Psychiatric Neuroimaging (LIM 21), Department of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil., Hallak JEC; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil.

Publikováno v: Cannabis and cannabinoid research [Cannabis Cannabinoid Res] 2022 Oct; Vol. 7 (5), pp. 658-669. Date of Electronic Publication: 2021 Oct 07.

Efficacy and Safety of Cannabidiol Plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout Among Frontline Health Care Workers During the COVID-19 Pandemic: A Randomized Clinical Trial.

Autor: Crippa JAS; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil., Zuardi AW; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil., Guimarães FS; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil.; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Campos AC; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., de Lima Osório F; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil., Loureiro SR; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Dos Santos RG; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil., Souza JDS; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Ushirohira JM; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Pacheco JC; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Ferreira RR; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Mancini Costa KC; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Scomparin DS; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Scarante FF; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Pires-Dos-Santos I; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Mechoulam R; Institute for Drug Research, School of Pharmacy, Hebrew University of Jerusalem, Jerusalem, Israel., Kapczinski F; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil.; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada.; Department of Psychiatry, Faculty of Medicine, Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Fonseca BAL; Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Esposito DLA; Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Pereira-Lima K; Department of Psychiatry, University of Michigan Medical School, Ann Arbor.; Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil., Sen S; Department of Psychiatry, University of Michigan Medical School, Ann Arbor., Andraus MH; Chromatox Laboratory, São Paulo, Brazil., Hallak JEC; Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.; National Institute for Science and Technology-Translational Medicine, São Paulo, Brazil.

Publikováno v: JAMA network open [JAMA Netw Open] 2021 Aug 02; Vol. 4 (8), pp. e2120603. Date of Electronic Publication: 2021 Aug 02.