SATB1 Chromatin Loops Regulate Megakaryocyte/Erythroid Progenitor Expansion by Facilitating HSP70 and GATA1 Induction.

Autor: Wilkes MC; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA, USA., Chae HD; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA, USA., Scanlon V; Department of Laboratory Medicine, Yale Stem Cell Center, Yale Cooperative Center of Excellence in Hematology, Yale School of Medicine, New Haven, CT, USA., Cepika AM; Institute for Stem Cell Biology and Regenerative Medicine, Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Wentworth EP; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA, USA., Saxena M; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA, USA., Eskin A; Department of Pathology and Laboratory Medicine¸ David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Chen Z; Department of Pathology and Laboratory Medicine¸ David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Glader B; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA, USA., Grazia Roncarolo M; Institute for Stem Cell Biology and Regenerative Medicine, Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Nelson SF; Department of Pathology and Laboratory Medicine¸ David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Sakamoto KM; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA, USA.

Publikováno v: Stem cells (Dayton, Ohio) [Stem Cells] 2023 Jun 15; Vol. 41 (6), pp. 560-569.

Downregulation of SATB1 by miRNAs reduces megakaryocyte/erythroid progenitor expansion in preclinical models of Diamond-Blackfan anemia.

Autor: Wilkes MC; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA., Scanlon V; Yale Stem Cell Center, Department of Pathology, Yale School of Medicine, Yale University, New Haven, CT., Shibuya A; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA., Cepika AM; Institute for Stem Cell Biology and Regenerative Medicine, Department of Genetics, Stanford University School of Medicine, Stanford, CA., Eskin A; Department of Pathology and Laboratory Medicine¸ David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA., Chen Z; Department of Pathology and Laboratory Medicine¸ David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA., Narla A; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA., Glader B; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA., Roncarolo MG; Institute for Stem Cell Biology and Regenerative Medicine, Department of Genetics, Stanford University School of Medicine, Stanford, CA., Nelson SF; Department of Pathology and Laboratory Medicine¸ David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA., Sakamoto KM; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, CA. Electronic address: kmsakamo@stanford.edu.

Publikováno v: Experimental hematology [Exp Hematol] 2022 Jul; Vol. 111, pp. 66-78. Date of Electronic Publication: 2022 Apr 20.

Current understanding of human megakaryocytic-erythroid progenitors and their fate determinants.

Autor: Kwon N; Department of Cell Biology.; Yale Stem Cell Center., Thompson EN; Department of Cell Biology.; Yale Stem Cell Center., Mayday MY; Yale Stem Cell Center.; Department of Pathology., Scanlon V; Yale Stem Cell Center.; Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, USA., Lu YC; Yale Stem Cell Center.; Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, USA., Krause DS; Department of Cell Biology.; Yale Stem Cell Center.; Department of Pathology.; Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

Publikováno v: Current opinion in hematology [Curr Opin Hematol] 2021 Jan; Vol. 28 (1), pp. 28-35.

miR-1915-3p regulates megakaryocytic and erythroid differentiation by targeting SOCS4.

Autor: Yuan, Xin¹ (AUTHOR), Liu, Pengcong¹ (AUTHOR), Xu, Lei¹ (AUTHOR), Liang, Liqing¹ (AUTHOR), Dong, Qian¹ (AUTHOR), Fan, Tao¹ (AUTHOR), Yue, Wen¹ (AUTHOR), Qu, Mingyi¹ (AUTHOR) minyeequ@126.com, Pei, Xuetao¹ (AUTHOR) peixt@bmi.ac.cn, Xie, Xiaoyan¹ (AUTHOR) xiex13@126.com

Publikováno v: Thrombosis Journal. 8/9/2024, Vol. 22 Issue 1, p1-11. 11p.

Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice.

Autor: Xavier-Ferrucio J; Department of Laboratory Medicine.; Yale Stem Cell Center., Scanlon V; Department of Laboratory Medicine.; Yale Stem Cell Center., Li X; Department of Pathology., Zhang PX; Department of Laboratory Medicine.; Yale Stem Cell Center., Lozovatsky L; Department of Pathology., Ayala-Lopez N; Department of Laboratory Medicine.; Yale Stem Cell Center., Tebaldi T; Section of Hematology, Department of Internal Medicine.; Yale Comprehensive Cancer Center, and.; Yale Center for RNA Science and Medicine, Yale School of Medicine, New Haven, CT; and., Halene S; Yale Stem Cell Center.; Section of Hematology, Department of Internal Medicine.; Yale Comprehensive Cancer Center, and.; Yale Center for RNA Science and Medicine, Yale School of Medicine, New Haven, CT; and., Cao C; Department of Pathology, Boston Children's Hospital, Boston, MA., Fleming MD; Department of Pathology, Boston Children's Hospital, Boston, MA., Finberg KE; Department of Pathology., Krause DS; Department of Laboratory Medicine.; Yale Stem Cell Center.; Department of Pathology.

Publikováno v: Blood [Blood] 2019 Oct 31; Vol. 134 (18), pp. 1547-1557.