Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization

Autor: Panettieri Reynold A, Russo Scott J, Scanlon Seth T, Tomer Yaniv, Beers Michael F, Atochina Elena N, Haczku Angela

Publikováno v: Respiratory Research, Vol 4, Iss 1, p 15 (2003)

Abstract Background C57BL/6 mice have attenuated allergic airway hyperresponsiveness (AHR) when compared with Balb/c mice but the underlying mechanisms remain unclear. SP-D, an innate immune molecule with potent immunosuppressive activities may have

Externí odkaz: https://doaj.org/article/5178f17f582d4dbda0f0bfc850691b65

PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF.

Autor: Sulkowski PL; Department of Genetics, Yale University, New Haven, Connecticut., Scanlon SE; Department of Experimental Pathology, Yale University, New Haven, Connecticut., Oeck S; Department of Therapeutic Radiology, Yale University, New Haven, Connecticut.; Institute of Cell Biology (Cancer Research), University of Duisburg-Essen, Essen, Germany., Glazer PM; Department of Genetics, Yale University, New Haven, Connecticut. peter.glazer@yale.edu.; Department of Therapeutic Radiology, Yale University, New Haven, Connecticut.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2018 Aug; Vol. 16 (8), pp. 1241-1254. Date of Electronic Publication: 2018 May 08.

Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy.

Autor: Gupta A; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, USA., Quijano E; Department of Biomedical Engineering, Yale University, New Haven, CT 06520, USA., Liu Y; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, USA., Bahal R; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA., Scanlon SE; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, USA., Song E; Department of Biomedical Engineering, Yale University, New Haven, CT 06520, USA., Hsieh WC; Department of Chemistry and Center for Nucleic Acids Science and Technology (CNAST), Carnegie Mellon University, Pittsburgh, PA 15213, USA., Braddock DE; Department of Pathology, Yale University, New Haven, CT 06510, USA., Ly DH; Department of Chemistry and Center for Nucleic Acids Science and Technology (CNAST), Carnegie Mellon University, Pittsburgh, PA 15213, USA., Saltzman WM; Department of Biomedical Engineering, Yale University, New Haven, CT 06520, USA., Glazer PM; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, USA; Department of Genetics, Yale University, New Haven, CT 06510, USA. Electronic address: peter.glazer@yale.edu.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2017 Dec 15; Vol. 9, pp. 111-119. Date of Electronic Publication: 2017 Sep 12.

2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.

Autor: Sulkowski PL; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA., Corso CD; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA., Robinson ND; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA., Scanlon SE; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Experimental Pathology, Yale University School of Medicine, New Haven, CT 06520, USA., Purshouse KR; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA., Bai H; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA., Liu Y; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA., Sundaram RK; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA., Hegan DC; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA., Fons NR; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Experimental Pathology, Yale University School of Medicine, New Haven, CT 06520, USA., Breuer GA; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Experimental Pathology, Yale University School of Medicine, New Haven, CT 06520, USA., Song Y; Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Mishra-Gorur K; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06520, USA., De Feyter HM; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT 06520, USA., de Graaf RA; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT 06520, USA., Surovtseva YV; Yale Center for Molecular Discovery, West Haven, CT 06516, USA., Kachman M; Michigan Regional Comprehensive Metabolomics Resource Core, National Institute of Environmental Health Sciences (NIEHS) Children's Health Exposure Analysis Resource for Metabolomics, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Halene S; Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Günel M; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06520, USA., Glazer PM; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA. ranjit.bindra@yale.edu peter.glazer@yale.edu.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA., Bindra RS; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA. ranjit.bindra@yale.edu peter.glazer@yale.edu.; Department of Experimental Pathology, Yale University School of Medicine, New Haven, CT 06520, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2017 Feb 01; Vol. 9 (375).

Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.

Autor: Scanlon SE; Authors' Affiliations: Departments of Therapeutic Radiology, Experimental Pathology, and., Glazer PM; Authors' Affiliations: Departments of Therapeutic Radiology, Genetics, Yale University School of Medicine, New Haven, Connecticut peter.glazer@yale.edu.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2014 Jul; Vol. 12 (7), pp. 1016-28. Date of Electronic Publication: 2014 Mar 31.