Zobrazeno 1 - 10
of 977
pro vyhledávání: '"Scaffolding protein"'
Autor:
Jiahao Zhang, Huike Zhu, Linjing Li, Yuting Gao, Boyi Yu, Guorong Ma, Xiaodong Jin, Yingbiao Sun
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 4, Pp 1050-1060 (2024)
Long non-coding RNAs (LncRNAs) are a class of RNA molecules with nucleic acid lengths ranging from 200 bp to 100 kb that cannot code for proteins, which are diverse and widely expressed in both animals and plants. Scholars have found that lncRNAs can
Externí odkaz:
https://doaj.org/article/6e9c9e6340c64188bda0fbbc7fbb3b6c
Autor:
Nina Wittenmayer, Andonia Petkova-Tuffy, Maximilian Borgmeyer, Chungku Lee, Jürgen Becker, Andreas Böning, Sebastian Kügler, JeongSeop Rhee, Julio S. Viotti, Thomas Dresbach
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Synapse formation is critical for the wiring of neural circuits in the developing brain. The synaptic scaffolding protein S-SCAM/MAGI-2 has important roles in the assembly of signaling complexes at post-synaptic densities. However, the role of S-SCAM
Externí odkaz:
https://doaj.org/article/26ee08b1a7b74c4992e7013016014b28
Akademický článek
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Akademický článek
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Publikováno v:
Neural Regeneration Research, Vol 17, Iss 7, Pp 1454-1461 (2022)
Ischemic and traumatic insults to the central nervous system account for most serious acute and fatal brain injuries and are usually characterized by primary and secondary damage. Secondary damage presents the greatest challenge for medical staff; ho
Externí odkaz:
https://doaj.org/article/27a67e0fe8ce429396d31a68d0a70c16
Autor:
Karl Foley, Haider Altimimi, Hailong Hou, Yu Zhang, Cody McKee, Makaía M. Papasergi-Scott, Hongtian Yang, Abigail Mayer, Nancy Ward, David M. MacLean, Angus C. Nairn, David Stellwagen, Houhui Xia
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Inhibitor-2 (I-2) is a prototypic inhibitor of protein phosphatase-1 (PP1), a major serine-threonine phosphatase that regulates synaptic plasticity and learning and memory. Although I-2 is a potent inhibitor of PP1 in vitro, our previous work has elu
Externí odkaz:
https://doaj.org/article/c086457f6f344661aadfe21d54e67f5d
Autor:
Komal Ramani, Nirmala Mavila, Aushinie Abeynayake, Maria Lauda Tomasi, Jiaohong Wang, Michitaka Matsuda, Eki Seki
Publikováno v:
eLife, Vol 11 (2022)
Trans-differentiation of hepatic stellate cells (HSCs) to activated state potentiates liver fibrosis through release of extracellular matrix (ECM) components, distorting the liver architecture. Since limited antifibrotics are available, pharmacologic
Externí odkaz:
https://doaj.org/article/b3f0685abbb14ba7bc5dfd49925d4b05
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1297 (2023)
Cytoplasmic phosphoinositides (PI) are critical regulators of the membrane–cytosol interface that control a myriad of cellular functions despite their low abundance among phospholipids. The metabolic cycle that generates different PI species is cru
Externí odkaz:
https://doaj.org/article/d7c03967a5dc46f58ebecafc5374fb22
Autor:
Nicole S. York, Juan C. Sanchez-Arias, Alexa C. H. McAdam, Joel E. Rivera, Laura T. Arbour, Leigh Anne Swayne
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
The ANK2 gene encodes for ankyrin-B (ANKB), one of 3 members of the ankyrin family of proteins, whose name is derived from the Greek word for anchor. ANKB was originally identified in the brain (B denotes “brain”) but has become most widely known
Externí odkaz:
https://doaj.org/article/999eed3ba63d4704ad6e434ca89c1be3
Autor:
Harsha Swamy, Angela J. Glading
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Recent advances have steadily increased the number of proteins and pathways known to be involved in the development of cerebral cavernous malformation (CCM). Our ability to synthesize this information into a cohesive and accurate signaling model is l
Externí odkaz:
https://doaj.org/article/1e9480b6a7034e51a0a28496e885a621