Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sbusisiwe Z. Mbatha"'
Autor:
Ashley J. Winter, Matthew T. Rowe, Angus N. M. Weir, Nahida Akter, Sbusisiwe Z. Mbatha, Paul D. Walker, Christopher Williams, Zhongshu Song, Paul R. Race, Christine L. Willis, Matthew P. Crump
Publikováno v:
Winter, A J, Rowe, M T, Weir, A N M, Akter, N, Mbatha, S Z, Walker, P D, Williams, C, Song, Z, Race, P R, Willis, C L & Crump, M P 2022, ' Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin ', Angewandte Chemie-International Edition, vol. 61, no. 50, e202212393 . https://doi.org/10.1002/anie.202212393
Mupirocin is a clinically important antibiotic produced by Pseudomonas fluorescens NCIMB 10586 that is assembled by a complex trans-AT polyketide synthase. The polyketide fragment, monic acid, is esterified by a 9-hydroxynonanoic acid (9HN) side chai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f3287f7bbdf8f76bb39e10e426174f
https://pubmed.ncbi.nlm.nih.gov/36227272
https://pubmed.ncbi.nlm.nih.gov/36227272
Autor:
Li-Chen Han, Matthew J. Byrne, James E. M. Stach, Carl O. Marsh, Nicholas R. Lees, Phillip W. Duke, Laurence Maschio, Sebastian Pagden‐Ratcliffe, Paul R. Race, Paul Curnow, Christine L. Willis, Sbusisiwe Z. Mbatha
Publikováno v:
Marsh, C O, Lees, N R, Han, L-C, Byrne, M J, Mbatha, S Z, Maschio, L, Pagden-Ratcliffe, S, Duke, P, Stach, J E M, Curnow, P, Willis, C L & Race, P R 2019, ' A Natural Diels-Alder Biocatalyst Enables Efficient [4 + 2] Cycloaddition Under Harsh Reaction Conditions ', ChemCatChem . https://doi.org/10.1002/cctc.201901285
Carbon‐carbon bond formation is a fundamental transformation in both synthetic chemistry and biosynthesis. Enzymes catalyze such reactions with exquisite selectivity which often cannot be achieved using non‐biological methods but may suffer from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1e17b701ba47a898ae6252727f14f4
https://doi.org/10.1002/cctc.201901285
https://doi.org/10.1002/cctc.201901285