Zobrazeno 1 - 10
of 363
pro vyhledávání: '"Sb, Seredenin"'
[PHARMACOLOGICAL STUDY OF NEW COMPOUNDS ACTING AS REGULATORS OF 18-KDA TRANSLOCATOR PROTEIN LIGANDS]
Publikováno v:
Europe PubMed Central
The interaction of new original 1-arylpyrrolo[1,2-a]pyrazine-3-carboxamide derivatives with mitochondrial translocator protein (MTP) 18 kDa has been studied by radioligand binding assay. Compounds GML-1 (Ki = 5.2 x 10⁻⁸ M) and GML-3 (Ki = 5.3 x 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6355ac1b4c0e23e7f0bc5db8385efa2e
https://pubmed.ncbi.nlm.nih.gov/27159950
https://pubmed.ncbi.nlm.nih.gov/27159950
Autor:
Lg, Kolik, Vp, Zherdev, Ss, Boiko, Ma, Konstantinopol Skii, Sy, Raskin, Tatiana Gudasheva, Va, Mart Yanov, Sb, Seredenin
Publikováno v:
Europe PubMed Central
Pharmacokinetics and pharmacological activity of GB-115 dipeptide anxiolytic after oral administration in the form of crystalline and micronized substances was studied in albino male rats. In contrast to crystalline, the micronized substance exhibite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6f19e9a45208af8349434f39eb343b5f
https://pubmed.ncbi.nlm.nih.gov/27017703
https://pubmed.ncbi.nlm.nih.gov/27017703
Autor:
Sa, Kryzhanovskiĭ, Lg, Kolik, Ib, Tsorin, Ekaterina Ionova, Vn, Stoliaruk, Mb, Vititnova, Av, Nadorova, Sb, Seredenin
Publikováno v:
Europe PubMed Central
Chronic alcohol abuse leads not only to a significant human psychic and social degradation, but also promotes the alcoholic cardiomyopathy formation, that is one of the leading causes of high mortality of alcoholics. However, to date in clinic there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6906143a5aa6e9ee7a681b50a269a63b
https://pubmed.ncbi.nlm.nih.gov/25272778
https://pubmed.ncbi.nlm.nih.gov/25272778
Autor:
Tatiana Gudasheva, Ga, Romanova, Fm, Shakova, So, Kotel Nikova, Iv, Barskov, Ev, Stel Mashuk, Sb, Seredenin
Publikováno v:
Europe PubMed Central
Neuroprotective and antiamnesic effects of human nerve growth factor (HNGF) synthetic dipeptide mimetic bis-(N-monosuccinyl-glycyl-lysine)hexamethylenediamide (GK-2h) has been studied on a model of bilateral photochemically induced focal ischemical b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4e6e0fa99ab9f097518cbde00a064bd3
https://pubmed.ncbi.nlm.nih.gov/23240153
https://pubmed.ncbi.nlm.nih.gov/23240153
Publikováno v:
Europe PubMed Central
The effects of GB-115 dipeptide, a retroanalog of endogenous CCK-4, on the behavioral indices in "elevated plus maze" (EPM) test and on the content of biogenic amines in the brain structures after discontinuation of a chronic administration of benzod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::42de4c5213eb4bf1cef3b60a057379f6
https://pubmed.ncbi.nlm.nih.gov/22238979
https://pubmed.ncbi.nlm.nih.gov/22238979
Autor:
Lg, Kolik, Tl, Garibova, Sa, Litvinova, Al, Kuznetsova, Ig, Kapitsa, Ia, Kadnikov, Ma, Konstantinopol Skiĭ, Tatiana Gudasheva, Ta, Voronina, Sb, Seredenin
Publikováno v:
Europe PubMed Central
Effects of GB-115, an anxiolytic L-triptophan-containing dipeptide, based on the endogenous tetrapeptide cholecystokinin, were evaluated during and after withdrawal of its long-term administration to rats in comparison with diazepam. It was shown usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffe89b6eca8e810d7830a0a913f2a396
https://pubmed.ncbi.nlm.nih.gov/21899090
https://pubmed.ncbi.nlm.nih.gov/21899090
Autor:
Vp, Zherdev, Ss, Boĭko, Nv, Mesonzhnik, Sa, Appolonova, Gn, Rodchenkov, Ru, Ostrovskaia, Tatiana Gudasheva, Sb, Seredenin
Publikováno v:
Europe PubMed Central
The metabolism and pharmacokinetics of a new neurotensine-derived dipeptide drug dilept (N-caproyl-L-prolyltyrosine methyl ester) and its tentative metabolites after intravenous and peroral administration of the parent drug and its tabletized form in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c52cc3c6e72fa66f1e96fdf8c8da6cf3
https://pubmed.ncbi.nlm.nih.gov/19642587
https://pubmed.ncbi.nlm.nih.gov/19642587
Publikováno v:
Europe PubMed Central
The paper describes pharmacological properties of the new nootropic drug noopept created using an original approach based on the imitation of a nonpeptide nootrope structure by means of the short-peptide design. In particular, the structure of pyrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::24080863d07f8c9116c976fb5a8bc65d
https://pubmed.ncbi.nlm.nih.gov/12596521
https://pubmed.ncbi.nlm.nih.gov/12596521
Autor:
Ru, Ostrovskaia, La, Liapina, Ve, Pastorova, Mirzoev TKh, Tatiana Gudasheva, Sb, Seredenin, Ip, Ashmarin
Publikováno v:
Europe PubMed Central
The experiments in vivo showed that the new nootropic prolyl-containing GVS-111 produces an antithrombotic effect, influencing various stages of the blood coagulation process. GVS-111 exhibits anticoagulant and fibrinolytic properties and enhances fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a03ecaa1114858e642085f8a27082055
https://pubmed.ncbi.nlm.nih.gov/12109290
https://pubmed.ncbi.nlm.nih.gov/12109290
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::43dce87b798f6c5429ed742f93409e9f
https://pubmed.ncbi.nlm.nih.gov/10599497
https://pubmed.ncbi.nlm.nih.gov/10599497