Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sayuri Uehara"'
Publikováno v:
Journal of Craniofacial Surgery. 32:1480-1482
Noncontact optical surface scanners have been used to evaluate facial soft tissues. Appropriate evaluation of patients with cleft lip and palate requires comprehensible assessment of the changes in their pre- and post-orthodontic soft tissue and faci
Autor:
Masahiro Katoh, Tadahiro Nambu, Takahiro Fukuroda, Takumi Sakai, Sayuri Uehara, Masaru Nishikibe
Publikováno v:
Biochemical and Biophysical Research Communications. 384:173-179
Patients with diabetes are under a hypercoagulable state leading to generation of thrombin. It is not known whether thrombin plays a role in the progression of diabetic nephropathy. We analyzed gene expression of two thrombin receptors, protease-acti
Publikováno v:
Journal of Craniofacial Surgery; 2021, Vol. 32 Issue 4, p1480-1482, 3p
Autor:
Sayuri Uehara, Hiroyoshi Matsumoto, Hisashi Ohta, Masayuki Kemi, Masaru Nishikibe, Minoru Sasaki, Kazuhiro Taguchi
Publikováno v:
Life Sciences. 75:869-880
Pathological changes in glomerular structure are typically associated with the progression of diabetic nephropathy. The involvement of angiotensin II (AII) in pathogenesis of diabetic nephropathy has been extensively studied and the therapeutic advan
Publikováno v:
Kidney International. 64(5):1632-1642
Vitamin D 3 up-regulated protein-1 regulates collagen expression in mesangial cells. Background Hyperglycemia is a known risk factor in the pathogenesis of nephropathy, and collagen accumulation due to an increase reactive oxygen species (ROS) has be
Autor:
Hiromasa Okada, Sayuri Uehara, Takanori Ikeda, Norikazu Ohtake, Megumu Okada, Miho Nishino, Takashi Hayama, Kenji Niiyama, Michihiro Saito, Masaru Nishikibe
Publikováno v:
Journal of Hypertension. 18:1815-1823
Objective To examine the chronic effects of a newly synthesized, potent and selective endothelin (ET) ET A receptor antagonist, J-105859, on mortality in salt-loaded Dahl salt-sensitive (DS) rats and to confirm the potential of this compound as an ET
Autor:
Noriko KAJIWARA, Fumihiro SUGIYAMA, Youko GOTO, Yoshihiro SUGIYAMA, Akiyoshi FUKAMIZU, Sayuri UEHARA, Kei-ichi SUGIMURA, Kazuo MURAKAMI, Ryoji HOKAO, Fumiaki AKAHORI, Ken-ichi YAGAMI
Publikováno v:
Experimental Animals. 42:463-466
We used pregnant and pseudopregnant Wistar-Imamichi rats, prepared at a breeding farm, for production of transgenic rats. The donor and recipient rats were transported to our facility for ova manipulation and embryo implantation, respectively. As a f
Autor:
Sayuri Uehara, Nobuhiko Nomura, Kimiyasu Shiraki, Hiroyuki Egawa, Hidehiro Sangawa, Kazumi Takahashi, Kyo Kozaki, Yousuke Furuta, Masako Kuno-Maekawa
Publikováno v:
Antimicrobial agents and chemotherapy. 49(3)
T-705, a substituted pyrazine compound, has been found to exhibit potent anti-influenza virus activity in vitro and in vivo. In a time-of-addition study, it was indicated that T-705 targeted an early to middle stage of the viral replication cycle but
Autor:
Akiyoshi Fukamizu, Tetsuya Kanno, Sayuri Uehara, Masaru Nishikibe, Minoru Tsuchida, Minoru Sasaki
Publikováno v:
International Journal of Molecular Medicine.
We previously generated a strain of transgenic mice carrying the human renin gene, hRN8-12, in the background of C57BL/6j. In this study, we discovered that hRN8-12 male mice, but not females, developed obesity starting at 15 weeks of age. The body w
Autor:
Kazuo Murakami, N Nishijho, Ken-ichi Yagami, Sayuri Uehara, Fumihiro Sugiyama, Keiji Tanimoto, Yoshihiko Kakinuma, Akiyoshi Fukamizu, K. Taniguchi
Publikováno v:
International journal of molecular medicine. 1(3)
a fpreviously produced angiotensinogen-deficient mice, i.e. mice with deleted renin-angiotensin system (RAS), with a genetic background on C57BL/6J - C57BL/6J-agt (-/-) -, but no C57BL/6J-agt (-/-) which survived long enough to be weaned. In the pres