Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sayonarah C. Rocha"'
Autor:
Sayonarah C. Rocha, Luis Eduardo M. Quintas, Natasha Paixão, Vanessa Faria Cortes, Gisele Capanema de Oliveira, Silmara L.G. Alves, José A.F.P. Villar, Leandro A. Barbosa, Marco Túlio C. Pessôa, François Noël, Miliane Alves da Silva Lopes
Publikováno v:
The Journal of Membrane Biology. 254:487-497
Na,K-ATPase (NKA) and cardiotonic steroids (CTS) have shown potent cytotoxic and anticancer effects. Here, we have synthesized a series of CTS digoxin derivatives (γ-benzylidene) with substitutions in the lactone ring and evaluated the cytotoxicity
Autor:
Lara Persich, Fátima Regina Mena Barreto Silva, Cláudia Maria Oliveira Simões, Vanessa Faria Cortes, Sayonarah C. Rocha, Carlos Frederico Leite Fontes, Fernão Castro Braga, Ana Carolina Pacheco Ramos, Wolfgang Kreis, Andre Dagostin, Danusa Menegaz, Jennifer Munkert, Rodrigo Maia de Pádua, Leandro A. Barbosa, Naira Fernanda Zanchett Schneider
Publikováno v:
Molecular and Cellular Biochemistry. 476:1825-1848
Cardiac glycosides (CGs) are useful drugs to treat cardiac illnesses and have potent cytotoxic and anticancer effects in cultured cells and animal models. Their receptor is the Na+,K+ ATPase, but other plasma membrane proteins might bind CGs as well.
Autor:
Sayonarah C Rocha, Marco T C Pessoa, Luiza D R Neves, Silmara L G Alves, Luciana M Silva, Herica L Santos, Soraya M F Oliveira, Alex G Taranto, Moacyr Comar, Isabella V Gomes, Fabio V Santos, Natasha Paixão, Luis E M Quintas, François Noël, Antonio F Pereira, Ana C S C Tessis, Natalia L S Gomes, Otacilio C Moreira, Ruth Rincon-Heredia, Fernando P Varotti, Gustavo Blanco, Jose A F P Villar, Rubén G Contreras, Leandro A Barbosa
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108776 (2014)
Cardiotonic steroids are used to treat heart failure and arrhythmia and have promising anticancer effects. The prototypic cardiotonic steroid ouabain may also be a hormone that modulates epithelial cell adhesion. Cardiotonic steroids consist of a ste
Externí odkaz:
https://doaj.org/article/be6b9f94d29e4b688e9429a2fc67ac6a
Autor:
Sven Wach, Alex Gutterres Taranto, Sayonarah C. Rocha, Leandro A. Barbosa, Naira Fernanda Zanchett Schneider, Jennifer Munkert, Fernão Castro Braga, Vanessa Faria Cortes, Rodrigo Maia de Pádua, Helge Taubert, Izabella Thaís Silva, Cláudia Maria Oliveira Simões, Wolfgang Kreis, Ana Carolina Pacheco Ramos, Elke Nolte
Publikováno v:
Biomedicine & Pharmacotherapy. 107:464-474
Cardiac glycosides (CGs) are natural compounds used to treat congestive heart failure. They have garnered attention as a potential cancer treatment option, especially because they bind to Na+/K+-ATPase as a target and activate intracellular signaling
Autor:
Naira Fernanda Zanchett, Schneider, Danusa, Menegaz, Andre Luiz Andreotti, Dagostin, Lara, Persich, Sayonarah C, Rocha, Ana Carolina Pacheco, Ramos, Vanessa Faria, Cortes, Carlos Frederico Leite, Fontes, Rodrigo Maia, de Pádua, Jennifer, Munkert, Wolfgang, Kreis, Fernão Castro, Braga, Leandro A, Barbosa, Fátima Regina Mena Barreto, Silva, Cláudia Maria Oliveira, Simões
Publikováno v:
Molecular and cellular biochemistry. 476(4)
Cardiac glycosides (CGs) are useful drugs to treat cardiac illnesses and have potent cytotoxic and anticancer effects in cultured cells and animal models. Their receptor is the Na
Autor:
Fernão Castro Braga, Lara Persich, Naira Fernanda Zanchett Schneider, Vanessa Faria Cortes, Sayonarah C. Rocha, Rodrigo Maia de Pádua, Leandro A. Barbosa, Izabella Thaís Silva, Jennifer Munkert, Alex Gutterres Taranto, Wolfgang Kreis, Cláudia Maria Oliveira Simões, Ana Carolina Pacheco Ramos
Publikováno v:
Biomedicine & Pharmacotherapy. 97:684-696
Cardiac glycosides (CGs) are natural compounds widely used to treat several cardiac conditions and more recently have been recognized as potential antitumor agents. They are known as Na,K-ATPases ligands, which is a promising drug target in cancer. I
Autor:
José A.F.P. Villar, Rosy Iara Maciel de Azambuja Ribeiro, Gustavo Blanco, Jessica M M Valadares, Jeffrey McDermott, Fernando de Pilla Varotti, Cristoforo Scavone, Simone C. Silva, Sayonarah C. Rocha, Leandro A. Barbosa, Marco Túlio C. Pessôa, Gladis Sánchez
Publikováno v:
Steroids
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cardiotonic steroids (CTS) are agents traditionally known for their capacity to bind to the Na,K-ATPase (NKA), affecting the ion transport and the contraction of the heart. Natural CTS have been shown to also have effects on cell signaling pathways.
Autor:
Sayonarah C. Rocha, Rubén G. Contreras, Leandro A. Barbosa, Mariana Alves Resende Salgado, Carlos Frederico Leite Fontes, Hérica de Lima Santos, Duane Gischewski Pereira, José Augusto Fp Villar, Vanessa Faria Cortes
Publikováno v:
Journal of cellular biochemistry. 119(4)
Cisplatin and other platinum-containing drugs have played a crucial role in anticancer treatments for over 30 years. However, treatment with cisplatin may cause serious side effects, such as myelosuppression, nausea, ototoxicity, nephrotoxicity, and
Autor:
Naira Fernanda Zanchett Schneider, Wolfgang Kreis, Izabella Thaís Silva, Alex Gutterres Taranto, Cláudia Maria Oliveira Simões, Fernão Castro Braga, Rodrigo Maia de Pádua, Sayonarah C. Rocha, Lara Persich, Annelise Carvalho, Ana Carolina Pacheco Ramos, Lucas Lourenço Marostica, Leandro A. Barbosa
Publikováno v:
Molecular and cellular biochemistry. 428(1-2)
Cardenolides are cardiac glycosides, mostly obtained from natural sources. They are well known for their inhibitory action on the Na,K-ATPase, an effect that regulates cardiovascular alterations such as congestive heart failure and atrial arrhythmias
Autor:
Soraya M.F. Oliveira, Isabella V. Gomes, Silmara L.G. Alves, Alex Gutterres Taranto, Leandro A. Barbosa, José A.F.P. Villar, François Noël, Hérica de Lima Santos, Luiza D.R. Neves, Luis Eduardo M. Quintas, Sayonarah C. Rocha, Fábio Vieira dos Santos, Marco Túlio C. Pessôa, Luciana Miato Gonçalves Silva
Publikováno v:
ResearcherID
Web of Science
Web of Science
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bd9131481a299088b329236419d52a
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000319883504248&KeyUID=WOS:000319883504248
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000319883504248&KeyUID=WOS:000319883504248