Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sayoko Saito"'
Elimination of Tumorigenic Human Pluripotent Stem Cells by a Recombinant Lectin-Toxin Fusion Protein
Autor:
Hiroaki Tateno, Yasuko Onuma, Yuzuru Ito, Fumi Minoshima, Sayoko Saito, Madoka Shimizu, Yasuhiko Aiki, Makoto Asashima, Jun Hirabayashi
Publikováno v:
Stem Cell Reports, Vol 4, Iss 5, Pp 811-820 (2015)
The application of stem-cell-based therapies in regenerative medicine is hindered by the tumorigenic potential of residual human pluripotent stem cells. Previously, we identified a human pluripotent stem-cell-specific lectin probe, called rBC2LCN, by
Externí odkaz:
https://doaj.org/article/6743cf5c3e68469e83275a88df19bca8
Publikováno v:
Molecules, Vol 22, Iss 7, p 1151 (2017)
The use of human pluripotent stem cells (hPSCs) such as human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) in regenerative medicine is hindered by their tumorigenic potential. Previously, we developed a recombinant l
Externí odkaz:
https://doaj.org/article/aa7986f66f8141b4ab6818d6f8d7cb4f
Autor:
Yu Yang, Yoshimasa Akashi, Osamu Shimomura, Hiroaki Tateno, Sayoko Saito, Keiko Hiemori, Yoshihiro Miyazaki, Tomoaki Furuta, Daichi Kitaguchi, Yukihito Kuroda, Louphrasitthiphol Pakavarin, Tatsuya Oda
Publikováno v:
Gastric Cancer. 25:896-905
Signet ring cell carcinoma (SRC) is a distinct subtype of gastric cancer (GC); however, the specific characteristics of cancer cell surface glycans and glycosylation remain unclear. In this study, we investigated SRC-specific glycans using lectin mic
Publikováno v:
Analysis & Sensing. 3
Publikováno v:
Analysis & Sensing. 3
Autor:
Hiroaki Tateno, Tomoko Watanabe, Kayo Hasehira, Toshio Imai, Jungo Kakuta, Kayo Kiyoi, Sayoko Saito
Publikováno v:
Biochemical and Biophysical Research Communications. 532:647-654
Human induced pluripotent stem cells (hiPSCs) are useful starting materials for the generation of cell therapy products, due to their pluripotency and ability to self-renew. Quality control of hiPSCs is extremely important in creating a stable supply
Autor:
Kayo Kiyoi, Yoshikazu Haramoto, Tomoko Watanabe, Sayoko Saito, Shuuji Mawaribuchi, Hiroaki Tateno, Keiko Hiemori
Publikováno v:
Biochemical and Biophysical Research Communications. 529:575-581
Quality control for human induced pluripotent stem cells (hiPSCs) is important for efficient and stable production of hiPSC-derived cell therapy products to be used for transplantation. During cell culture, hiPSCs spontaneously undergo morphological
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Glycans are one of the major building blocks of extracellular vesicles (EVs). However, their roles and applications have not been completely explored. Here, we analyzed the glycome of EVs derived from human induced pluripotent stem cells (hiPSCs) usi
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 676
International Journal of Molecular Sciences, Vol 23, Iss 676, p 676 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 676, p 676 (2022)
International Journal of Molecular Sciences
Lectins, carbohydrate-binding proteins, are attractive biomolecules for medical and biotechnological applications. Many lectins have multiple carbohydrate recognition domains (CRDs) and strongly bind to specific glycans through multivalent binding ef
Publikováno v:
Chembiochem : a European journal of chemical biology. 20(12)
Human pluripotent stem cells (hPSCs) are attractive resources for regenerative medicine, but medical applications are hindered by their tumorigenic potential. Previously, a hPSC-specific lectin probe, rBC2LCN, was identified through comprehensive gly