Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Sayoko Ihara"'
Autor:
Airi Jo-Watanabe, Toshiki Inaba, Takahiro Osada, Ryota Hashimoto, Tomohiro Nishizawa, Toshiaki Okuno, Sayoko Ihara, Kazushige Touhara, Nobutaka Hattori, Masatsugu Oh-Hora, Osamu Nureki, Takehiko Yokomizo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Homoeostatic regulation of the acid–base balance is essential for cellular functional integrity. However, little is known about the molecular mechanism through which the acid–base balance regulates cellular responses. Here, we report tha
Externí odkaz:
https://doaj.org/article/f95ce9a7d6854817a73fa616defc04d5
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53298 (2013)
Heregulin (HRG) β1 signaling promotes scattering of MCF7 cells by inducing breakdown of adherens and tight junctions. Here, we show that stimulation with HRG-β1 causes the F-actin backbone of junctions to destabilize prior to the loss of adherent p
Externí odkaz:
https://doaj.org/article/040ef11b836d45b9b239f7c9853a70f9
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29599 (2011)
Signal transduction and cell responses after stimulation with heregulin β-1 (HRG) are examined in HCC2998 and MKN45-1 cells, which have been used for a model system to study the formation of signet ring carcinomas, one of poorly differentiated adeno
Externí odkaz:
https://doaj.org/article/79ca4d8e843e4a779749a359d09e2831
Autor:
Yasuhisa Fukui, Sayoko Ihara
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14180 (2010)
SWAP-70, a phosphatidylinositol trisphosphate (PtdIns(3,4,5)P(3)) binding protein, has been suggested to be involved in transformation of mouse embryo fibroblasts (MEFs) as well as membrane ruffling after growth factor stimulation of the cells. A mut
Externí odkaz:
https://doaj.org/article/177dea379c1847b0bdd1f64867956b45
Autor:
Satoshi Morinaga, Koji Nagata, Sayoko Ihara, Tomohiro Yumita, Yoshihito Niimura, Koji Sato, Kazushige Touhara
Publikováno v:
The Journal of biological chemistry. 298(11)
Insect gustatory receptors play roles in sensing tastants, such as sugars and bitter substances. We previously demonstrated that the BmGr9 silkworm gustatory receptor is a d-fructose-gated ion channel receptor. However, the molecular mechanism of how
Autor:
Yusuke Ihara, Hidehiko Wakabayashi, Ayumi Nagashima, Yoshihito Niimura, Yasuko Nogi, Sayoko Ihara, Kenji Kondo, Chiori Ijichi, Yuya Shimizu, Shingo Sugiyama, Kazushige Touhara
Publikováno v:
Chemical Senses. 44:465-481
In this study, we examined the mode of metabolism of food odorant molecules in the human nasal/oral cavity in vitro and in vivo. We selected 4 odorants, 2-furfurylthiol (2-FT), hexanal, benzyl acetate, and methyl raspberry ketone, which are potential
Publikováno v:
The Senses: A Comprehensive Reference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9856e466abcd6ba2ef2eacc6faf78b9
https://doi.org/10.1016/b978-0-12-809324-5.24175-8
https://doi.org/10.1016/b978-0-12-809324-5.24175-8
Autor:
Kazushige Touhara, Sayoko Ihara, Mika Shirasu, Nao Horio, Keiichi Yoshikawa, Narumi Sato-Akuhara, Aya Kato-Namba, Yoshihito Niimura
Publikováno v:
The Journal of Neuroscience. 36:4482-4491
Musk odors have been used widely for fragrance and medicine for >2000 years because of their fascinating scent and physiological effects. Therefore, fragrance manufacturers have been eager to develop high-quality musk compounds that are safe and easi
Autor:
Sayoko, Ihara, Kazushige, Touhara
Publikováno v:
Clinical calcium. 28(8)
Olfactory receptor(OR)genes constitute the largest gene family in mammals. Some of them have been shown to be expressed not only in the olfactory system, but also in various non-olfactory tissues. So far, the roles of such ectopically expressed ORs h
Autor:
Sayoko, Ihara, Kazushige, Touhara
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1820
Like in other sensory systems, adaptation is an essential process in the olfactory system, required for its proper functioning. However, the precise molecular mechanism underlying the adaptation process has not been fully understood, especially at th