Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Saygin Bilican"'
Autor:
Shady Sayed, Jan Kaslin, Stefano Suzzi, Volker Kroehne, Stefan Hans, Pertti Panula, Paul Wirsching, Sandra Spieß, Anja Machate, Saygin Bilican, Sylke Winkler, Avinash Chekuru, Michael Brand, Reiner Ahrendt, Svetlana Semenova
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 9, p e1009794 (2021)
PLoS Genetics, Vol 17, Iss 9, p e1009794 (2021)
LRRK2 gain-of-function is considered a major cause of Parkinson’s disease (PD) in humans. However, pathogenicity of LRRK2 loss-of-function in animal models is controversial. Here we show that deletion of the entire zebrafish lrrk2 locus elicits a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b433f543f7ad522ab4d4c5317fc4c0
Autor:
Stefano Suzzi, Reiner Ahrendt, Stefan Hans, Svetlana A Semenova, Avinash Chekuru, Paul Wirsching, Volker Kroehne, Saygın Bilican, Shady Sayed, Sylke Winkler, Sandra Spieß, Anja Machate, Jan Kaslin, Pertti Panula, Michael Brand
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009794 (2021)
LRRK2 gain-of-function is considered a major cause of Parkinson's disease (PD) in humans. However, pathogenicity of LRRK2 loss-of-function in animal models is controversial. Here we show that deletion of the entire zebrafish lrrk2 locus elicits a ple
Externí odkaz:
https://doaj.org/article/66a7d68b5aa74d34a2b220b852048894
Autor:
Shady Sayed, Stefan Hans, Pertti Panula, Sandra Spieß, Jan Kaslin, Sylke Winkler, Svetlana Semenova, Reiner Ahrendt, Stefano Suzzi, Saygin Bilican, Michael Brand
Publikováno v:
bioRxiv
LRRK2 mutations are a major cause of Parkinson’s disease. Pathogenicity of LRRK2 loss-of-function is controversial, as knockout in rodents reportedly induces no brain-specific effects and knockdown studies in zebrafish are conflicting. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a339ddad588566f512ec2670d52996
