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Dextrin conjugation to colistin inhibits its toxicity, cellular uptake and acute kidney injury in vivo .

Autor: Varache M; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk., Rizzo S; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk., Sayers EJ; School of Pharmacy and Pharmaceutical Sciences, Cardiff University CF10 3NB UK., Newbury L; Wales Kidney Research Unit, Division of Infection and Immunity, School of Medicine, College of Biomedical and Life Sciences, Cardiff University Cardiff CF14 4XN UK., Mason A; Wales Kidney Research Unit, Division of Infection and Immunity, School of Medicine, College of Biomedical and Life Sciences, Cardiff University Cardiff CF14 4XN UK., Liao CT; Systems Immunity Research Institute, Division of Infection and Immunity, School of Medicine, Cardiff University Cardiff CF14 4XN UK., Chiron E; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk., Bourdiec N; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk., Jones A; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk.; Cellular Pathology Department, University Dental Hospital, Cardiff and Vale University Health Board Cardiff CF14 4XY UK., Fraser DJ; Wales Kidney Research Unit, Division of Infection and Immunity, School of Medicine, College of Biomedical and Life Sciences, Cardiff University Cardiff CF14 4XN UK., Taylor PR; Systems Immunity Research Institute, Division of Infection and Immunity, School of Medicine, Cardiff University Cardiff CF14 4XN UK.; UK Dementia Research Institute at Cardiff Hadyn Ellis Building Maindy Road Cardiff CF24 4HQ UK., Jones AT; School of Pharmacy and Pharmaceutical Sciences, Cardiff University CF10 3NB UK., Thomas DW; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk.; Systems Immunity Research Institute, Division of Infection and Immunity, School of Medicine, Cardiff University Cardiff CF14 4XN UK., Ferguson EL; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk.

Publikováno v: RSC pharmaceutics [RSC Pharm] 2024 Feb 05; Vol. 1 (1), pp. 68-79. Date of Electronic Publication: 2024 Feb 05 (Print Publication: 2024).

Highly-fluorescent BODIPY-functionalised metallacages as drug delivery systems: synthesis, characterisation and cellular accumulation studies.

Autor: Aikman B; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 Garching b. München, Germany. angela.casini@tum.de., Bonsignore R; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 Garching b. München, Germany. angela.casini@tum.de.; Dipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche, Università degli Studi di Palermo, Viale delle Scienze, Edificio 17, 90128 Palermo, Italy., Woods B; Institute of Structural and Molecular Biology and Department of Biological Sciences, School of Science, Birkbeck University of London, Malet Street, London WC1E 7HX, UK., Doellerer D; Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands., Scotti R; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 Garching b. München, Germany. angela.casini@tum.de., Schmidt C; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 Garching b. München, Germany. angela.casini@tum.de., Heidecker AA; Catalysis Research Center & Department of Chemistry, Chair of Inorganic and Metal-Organic Chemistry, Technical University of Munich, Ernst-Otto-Fischer Str. 1, D-85748 Garching b. München, Germany., Pöthig A; Catalysis Research Center & Department of Chemistry, Chair of Inorganic and Metal-Organic Chemistry, Technical University of Munich, Ernst-Otto-Fischer Str. 1, D-85748 Garching b. München, Germany., Sayers EJ; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, CF10 3NB Cardiff, Wales, UK., Jones AT; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, CF10 3NB Cardiff, Wales, UK., Casini A; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 Garching b. München, Germany. angela.casini@tum.de.; Munich Data Science Institute, Technical University of Munich, D-85748 Garching b. München, Germany.

Publikováno v: Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2022 May 17; Vol. 51 (19), pp. 7476-7490. Date of Electronic Publication: 2022 May 17.