Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sayeh Gorjifard"'
Autor:
Sayeh Gorjifard, Tobias Jores, Jackson Tonnies, Nicholas A. Mueth, Kerry Bubb, Travis Wrightsman, Edward S. Buckler, Stanley Fields, Josh T. Cuperus, Christine Queitsch
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The 3’ end of a gene, often called a terminator, modulates mRNA stability, localization, translation, and polyadenylation. Here, we adapted Plant STARR-seq, a massively parallel reporter assay, to measure the activity of over 50,000 termin
Externí odkaz:
https://doaj.org/article/908d5cba8923462d9ec5479ec926226a
Publikováno v:
Journal of Biological Chemistry. 299:103426
Autor:
John S. Schneekloth, David R. Calabrese, Anaisa Quintanilla Arteaga, Aleksandra M. Michalowski, Beverly A. Mock, Sayeh Gorjifard, Snehal M. Gaikwad, Zheng-gang Liu, Jing Huang, Shuling Zhang, Daniel Connors, Zaw Phyo
Publikováno v:
Cancers
Volume 12
Issue 10
Cancers, Vol 12, Iss 2952, p 2952 (2020)
Volume 12
Issue 10
Cancers, Vol 12, Iss 2952, p 2952 (2020)
New approaches to target MYC include the stabilization of a guanine-rich, G-quadruplex (G4) tertiary DNA structure in the NHE III region of its promoter. Recent screening of a small molecule microarray platform identified a benzofuran, D089, that can
Autor:
Sayeh Gorjifard, Beverly A. Mock, Snehal M. Gaikwad, Shuling Zhang, V Keith Hughitt, Wendy Dubois, Ke Zhang, Tyler J Peat, John K. Simmons
Publikováno v:
Journal of cancer metastasis and treatment
Long-term genetic studies utilizing backcross and congenic strain analyses coupled with positional cloning strategies and functional studies identified Cdkn2a, Mtor, and Mndal as mouse plasmacytoma susceptibility/resistance genes. Tumor incidence dat
Autor:
Eric C. Polley, John K. Simmons, V Keith Hughitt, Ryan Dale, Sayeh Gorjifard, Jonathan J Keats, Beverly A. Mock, Aleksandra M. Michalowski
Publikováno v:
Cancer Research. 79:5113-5113
Recent years have seen an explosion in the availability of paired molecular profiling and drug screen data, providing an unprecedented opportunity for the development of targeted therapies based on an individual’s genetic background. Despite a numb
Autor:
Justin M. Lopchuk, Sayeh Gorjifard, Gordon W. Gribble, William L. Montgomery, Jerry P. Jasinski
Publikováno v:
Tetrahedron Letters. 54:6142-6145
2-Cyanoindole and N-methyl-2-cyanoindole undergo manganese(III)-mediated radical addition with activated methylene and methine compounds. Products of the methylene addition underwent additional oxidation during the course of the reaction to furnish t
Autor:
Lorangelly Rivera Torres, Ruth A. Woodward, Eryney Marrogi, Dariya Momot, Rao L. Divi, Ofelia A. Olivero, Marsha J. Sowers, Yongmin Liu, Sayeh Gorjifard, Miriam C. Poirier
Publikováno v:
The Journal of Infectious Diseases. 208:244-248
(See the major article by Andre-Schmutz et al on pages 235–43) Antiretroviral (ARV) drug combinations prevent the transmission of human immunodeficiency virus type 1 (HIV-1) [1] in approximately 99% of the 10 000 HIV-1-infected women who become pre
Autor:
Romina S. Goldszmid, Sayeh Gorjifard
The gut microbiota is a complex and dynamic microbial ecosystem that plays a fundamental role in host physiology. Locally, the gut commensal microbes/host symbiotic relationship is vital for barrier fortification, nutrient absorption, resistance agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8e984ac7aa84a5e8649705c8927b53
https://europepmc.org/articles/PMC6608064/
https://europepmc.org/articles/PMC6608064/
Autor:
Sayeh Gorjifard, Romina S. Goldszmid
Publikováno v:
Cell hostmicrobe. 18(6)
Blockade of immune checkpoint molecules, a group of molecules normally involved in maintaining self-tolerance and limiting T cell responses, has emerged as a breakthrough in cancer therapy. Two recent studies published in Science show that, in mice,
Autor:
John K. Simmons, Adriana Zingone, Aleksandra M. Michalowski, Sayeh Gorjifard, Anaisa Quintanilla-Artega, Jing Huang, Snehal M. Gaikwad, Beverly A. Mock, Ola Landgren, Nicholas J. Watson, Susana Najera
Publikováno v:
Cancer Research. 78:5850-5850
Multiple myeloma (MM) is a hematologic neoplasm characterized by malignant proliferation of plasma cells in the bone marrow. Proteasome inhibitors are widely used in treatment regimens for MM. Although initial responses to PI (e.g., bortezomib, carfi