Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Sayeh Agah"'
Unique allergen-specific human IgE monoclonal antibodies derived from patients with allergic disease
Autor:
Bryan R. E. Smith, Kristina Reid Black, Max Bermingham, Sayeh Agah, Jill Glesner, Serge A. Versteeg, Ronald van Ree, Glorismer Pena-Amelunxen, Lorenz Aglas, Scott A. Smith, Anna Pomés, Martin D. Chapman
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
IntroductionAllergic reactions are mediated by human IgE antibodies that bind to and cross-link allergen molecules. The sites on allergens that are recognized by IgE antibodies have been difficult to investigate because of the paucity of IgE antibodi
Externí odkaz:
https://doaj.org/article/fd41209d93dd4b2d988c7503b51658d6
Autor:
Rhys T. Meredith, Max D. Bermingham, Kirsten Bentley, Sayeh Agah, Abigail Aboagye-Odei, Ross A. R. Yarham, Hayley Mills, Muddassir Shaikh, Neil Hoye, Richard J. Stanton, David R. Chadwick, Maria A. Oliver
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionThe heterogeneity of the immunocompromised population means some individuals may exhibit variable, weak or reduced vaccine-induced immune responses, leaving them poorly protected from COVID-19 disease despite receiving multiple SARS-CoV-2
Externí odkaz:
https://doaj.org/article/66b536c9f70d4b08b5165d90765998a7
Autor:
Mayuresh M. Abhyankar, Barbara J. Mann, Jeffrey M. Sturek, Savannah Brovero, G. Brett Moreau, Anjali Sengar, Crystal M. Richardson, Sayeh Agah, Anna Pomés, Peter M. Kasson, Mark A. Tomai, Christopher B. Fox, William A. Petri
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-6 (2021)
Abstract We developed a SARS-CoV-2 spike subunit vaccine formulation containing dual TLR ligand liposome adjuvant. The vaccine-induced robust systemic neutralizing antibodies and completely protected mice from a lethal challenge. Two immunizations pr
Externí odkaz:
https://doaj.org/article/da4da1c7c88a4956b31769225afbc2c2
Autor:
Yugesh Kharel, Sayeh Agah, Tao Huang, Anna J Mendelson, Oluwafunmilayo T Eletu, Peter Barkey-Bircann, James Gesualdi, Jeffrey S Smith, Webster L Santos, Kevin R Lynch
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0192179 (2018)
Successful medicinal chemistry campaigns to discover and optimize sphingosine kinase inhibitors require a robust assay for screening chemical libraries and for determining rank order potencies. Existing assays for these enzymes are laborious, expensi
Externí odkaz:
https://doaj.org/article/42b1f7bb56ed403fa5674802e9803675
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174485 (2017)
The design of proteins that self-assemble into higher order architectures is of great interest due to their potential application in nanotechnology. Specifically, the self-assembly of proteins into ordered lattices is of special interest to the field
Externí odkaz:
https://doaj.org/article/c566e139cb494e25abbe72ae24680283
Autor:
Jeffrey M. Sturek, Savannah Brovero, Barbara J. Mann, Mark A. Tomai, G. Brett Moreau, Sayeh Agah, Anna Pomés, Mayuresh M. Abhyankar, Peter M. Kasson, William A. Petri, Anjali Sengar, Christopher B. Fox, Crystal M. Richardson
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 6, Iss 1, Pp 1-6 (2021)
npj Vaccines, Vol 6, Iss 1, Pp 1-6 (2021)
We developed a SARS-CoV-2 spike subunit vaccine formulation containing dual TLR ligand liposome adjuvant. The vaccine-induced robust systemic neutralizing antibodies and completely protected mice from a lethal challenge. Two immunizations protected a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a590491cd24c999e1ea22980e760fc
https://doi.org/10.1038/s41541-021-00399-0
https://doi.org/10.1038/s41541-021-00399-0
Autor:
Stephanie C, Filep, Kristina, Reid Black, Bryan R E, Smith, Denise S, Block, Anna, Kuklinska-Pijanka, Max, Bermingham, Maria A, Oliver, Catherine M, Thorpe, Zachary P, Schuhmacher, Sayeh, Agah, Sabina, Wuenschmann, Martin D, Chapman
Publikováno v:
Food Chemistry. 389:132986
The aim was to develop a fluorescent multiplex array for simultaneously measuring regulated food allergens using specific allergen protein molecules from peanut, tree nut, cow's milk, egg, soy, fish, shellfish, sesame, mustard and celery. Microsphere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36312a29416499ccbe450d6bae7a8877
https://doi.org/10.1016/j.foodchem.2022.132986
https://doi.org/10.1016/j.foodchem.2022.132986
Publikováno v:
The Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology
Rationale: Individuals with asthma may be at higher risk of becoming severely ill from COVID-19 which targets the respiratory tract and may cause asthma exacerbations. Serological testing can be useful to assess the true spread of COVID-19 and help p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8e4185c1dce9856c2ba98bbc3bce04
http://europepmc.org/articles/PMC7849525
http://europepmc.org/articles/PMC7849525
Autor:
Cathy Thorpe, Bryan Smith, Sabina Wuenschmann, Kristina Reid Black, Stephanie Filep, Sayeh Agah, Martin C. Chapman
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:AB144
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eb3883da46c9e07b324effdd010a00d
https://doi.org/10.1016/j.jaci.2020.12.521
https://doi.org/10.1016/j.jaci.2020.12.521
Autor:
Sayeh Agah, Sabina Wuenschmann, Thomas A. Randall, Anna Pomés, Lisa D. Vailes, Aurora Cabrera, Michael C. Fitzgerald, Geoffrey A. Mueller, Jill Glesner, Alexander C. Y. Foo
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:AB82
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::399d7337f543c5e60971b71fa514d4be
https://doi.org/10.1016/j.jaci.2020.12.316
https://doi.org/10.1016/j.jaci.2020.12.316