Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Sayeda Nasrin Alam"'
1
Neurokinin B Is Critical for Normal Timing of Sexual Maturation but Dispensable for Adult Reproductive Function in Female Mice
Autor: Stephanie B. Seminara, Kimberly H. Cox, Sayeda Nasrin Alam, Yee-Ming Chan, Cadence True
Publikováno v: Endocrinology. 156:1386-1397
Humans carrying mutations in neurokinin B (NKB) or the NKB receptor fail to undergo puberty due to decreased secretion of GnRH. Despite this pubertal delay, many of these patients go on to achieve activation of their hypothalamic-pituitary-gonadal ax
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec70a5923ed24984bbf117fa75b98b24
https://doi.org/10.1210/en.2014-1862
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2
Intestinal alkaline phosphatase promotes gut bacterial growth by reducing the concentration of luminal nucleotide triphosphates
Autor: H. Shaw Warren, Nondita S. Malo, Omeed Moaven, José Luis Millán, Sonoko Narisawa, Richard A. Hodin, Brishti Biswas, Konstantinos P. Economopoulos, Simon C. Robson, Abeba Teshager, Sarah S. Gul, Sulaiman R. Hamarneh, Nur Muhammad, Elizabeth L. Hohmann, Mussa M. Rafat Mohamed, Sayeda Nasrin Alam, Qingsong Tao, Madhu S. Malo
Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 306:G826-G838
The intestinal microbiota plays a pivotal role in maintaining human health and well-being. Previously, we have shown that mice deficient in the brush-border enzyme intestinal alkaline phosphatase (IAP) suffer from dysbiosis and that oral IAP suppleme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf15279cacd572ce63734380eaafcd2
https://doi.org/10.1152/ajpgi.00357.2013
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3
Intestinal Alkaline Phosphatase Prevents Antibiotic-Induced Susceptibility to Enteric Pathogens
Autor: Soumik Barua, Sathi Ghosh, Brishti Biswas, Halim Yammine, Rizwan Ahmed, Richard A. Hodin, Madhu S. Malo, Nondita S. Malo, Atul K. Bhan, Sayeda Nasrin Alam, Omeed Moaven, Kanakaraju Kaliannan, Atri Raychowdhury, Rakesh Biswas, Angela K. Moss, Madhury Ray, Nur Muhammad, Sulaiman R. Hamarneh
Publikováno v: Annals of Surgery. 259:715-722
To determine the efficacy of oral supplementation of the gut enzyme intestinal alkaline phosphatase (IAP) in preventing antibiotic-associated infections from Salmonella enterica serovar Typhimurium (S. Typhimurium) and Clostridium difficile.The intes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b3d1039cb791b1164fe19c3a016f43
https://doi.org/10.1097/sla.0b013e31828fae14
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4
Intestinal alkaline phosphatase inhibits the proinflammatory nucleotide uridine diphosphate
Autor: Madhu S. Malo, Elizabeth L. Hohmann, Richard A. Hodin, Halim Yammine, Kanakaraju Kaliannan, José Luis Millán, Omeed Moaven, Sayeda Nasrin Alam, Sundaram Ramasamy, Nur Muhammad, Angela K. Moss, H. Shaw Warren, Palak Patel, Abeba Teshager, Nondita S. Malo, Sulaiman R. Hamarneh, Sonoko Narisawa, Mussa M. Rafat Mohamed
Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 304:G597-G604
Uridine diphosphate (UDP) is a proinflammatory nucleotide implicated in inflammatory bowel disease. Intestinal alkaline phosphatase (IAP) is a gut mucosal defense factor capable of inhibiting intestinal inflammation. We used the malachite green assay
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14eb30143e4b6218eca93e56cd8318e5
https://doi.org/10.1152/ajpgi.00455.2012
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5
Prevention of antibiotic-associated metabolic syndrome in mice by intestinal alkaline phosphatase
Autor: S. Hakimian, Rizwan Ahmed, Mussa M. Rafat Mohamed, Kanakaraju Kaliannan, Palak Patel, Omeed Moaven, Caleb D. Phillips, Konstantinos P. Economopoulos, Sayeda Nasrin Alam, Naomi L. Ward, Madhu S. Malo, J. F. Haller, Abeba Teshager, Stephen B. Cox, Richard A. Hodin, Atul K. Bhan, Allan M. Goldstein
Publikováno v: Diabetes, obesitymetabolism. 18(5)
Aims To examine whether co-administration of intestinal alkaline phosphatase (IAP) with antibiotics early in life may have a preventive role against metabolic syndrome (MetS) in mice. Methods A total of 50 mice were allocated to four treatment groups
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeeed5124b3f9b8e4eabec75a924c96a
https://pubmed.ncbi.nlm.nih.gov/26876427
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6
Intestinal alkaline phosphatase prevents metabolic syndrome in mice
Autor: Richard A. Hodin, Palak Patel, Nur Muhammad, Abeba Teshager, Rizwan Ahmed, Sonoko Narisawa, Elizabeth L. Hohmann, S. Hakimian, Omeed Moaven, Mussa M. Rafat Mohamed, Sayeda Nasrin Alam, Seyed Mahdi Abtahi, Kanakaraju Kaliannan, Angela K. Moss, Madhury Ray, Madhu S. Malo, Sulaiman R. Hamarneh, José Luis Millán, Atul K. Bhan, Nondita S. Malo, Atri Raychowdhury, Konstantinos P. Economopoulos, H. Shaw Warren
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 110(17)
Metabolic syndrome comprises a cluster of related disorders that includes obesity, glucose intolerance, insulin resistance, dyslipidemia, and fatty liver. Recently, gut-derived chronic endotoxemia has been identified as a primary mediator for trigger
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f74a0072b8470020aa315bcf9ed5aff
https://pubmed.ncbi.nlm.nih.gov/23609332
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8
Local peritoneal irrigation with intestinal alkaline phosphatase is protective against peritonitis in mice
Autor: H. Shaw Warren, Angela K. Moss, Farzad Ebrahimi, Elizabeth L. Hohmann, Golam Mostafa, Sundaram Ramasamy, Brishti Biswas, Nur Muhammad, Kathryn T. Chen, Richard A. Hodin, Halim Yammine, Sayeda Nasrin Alam, Madhu S. Malo
Publikováno v: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 15(5)
The brush-border enzyme intestinal alkaline phosphatase (IAP) functions as a gut mucosal defense factor and detoxifies different toll-like receptor ligands. This study aimed to determine the therapeutic effects of locally administered calf IAP (cIAP)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f69052a4b53fec5f81594a1b495149
https://pubmed.ncbi.nlm.nih.gov/21360208
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9
Identification of specific targets for the gut mucosal defense factor intestinal alkaline phosphatase
Autor: Madhu S. Malo, Richard A. Hodin, Golam Mostafa, Sundaram Ramasamy, H. Shaw Warren, Sayeda Nasrin Alam, Skye Zeller, Kathryn T. Chen, Farzad Ebrahimi, Elizabeth L. Hohmann, Paul V. Johnson, Angela K. Moss
Publikováno v: American journal of physiology. Gastrointestinal and liver physiology. 299(2)
Intestinal alkaline phosphatase (IAP) is a small intestinal brush border enzyme that has been shown to function as a gut mucosal defense factor, but its precise mechanism of action remains unclear. We investigated the effects of IAP on specific bacte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecac27f37c662bcc7f557d87d3b056e5
https://pubmed.ncbi.nlm.nih.gov/20489044
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