Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Sayan Chakraborty"'
Autor:
Sydney Camfield, Sayan Chakraborty, Shailendra Kumar Dhar Dwivedi, Pijush Kanti Pramanik, Priyabrata Mukherjee, Resham Bhattacharya
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-14 (2024)
Abstract The canonical role of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) in repairing DNA double-strand breaks combined with its reported dysregulation in several malignancies has driven the development of DNA-PKcs inhibitors as t
Externí odkaz:
https://doaj.org/article/a0ed369677654f1ba846a319fd15e6fc
Autor:
Fengzhi Li, Xiang Ling, Sayan Chakraborty, Christos Fountzilas, Jianmin Wang, Anmbreen Jamroze, Xiaozhuo Liu, Pawel Kalinski, Dean G. Tang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-26 (2023)
Abstract There is increasing evidence indicating the significant role of DDX5 (also called p68), acting as a master regulator and a potential biomarker and target, in tumorigenesis, proliferation, metastasis and treatment resistance for cancer therap
Externí odkaz:
https://doaj.org/article/30e67990699f4a9691fd82d5b47de1b1
Autor:
Sayan Chakraborty, Divyaleka Sampath, Melissa Ong Yu Lin, Matthew Bilton, Cheng-Kuang Huang, Mui Hoon Nai, Kizito Njah, Pierre-Alexis Goy, Cheng-Chun Wang, Ernesto Guccione, Chwee-Teck Lim, Wanjin Hong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Replenishing key extracellular matrix (ECM) proteins facilitate wound healing through unclear mechanisms. Here the authors report that injury-triggered Agrin, an ECM proteoglycan, tunes a mechanocompetent niche by engaging MMP-12, thereby enforcing e
Externí odkaz:
https://doaj.org/article/66e7f31bc2564edc8b704e9a42602d0d
Publikováno v:
Asian Pacific Journal of Cancer Biology, Vol 6, Iss 2, Pp 155-160 (2021)
Background: RIZ1 is one of the tumor-suppressor genes that is silenced in many human cancers. Change in RIZ1 expression has not been reported in ESCC patients. Therefore, the aim of this study was to investigate the role of RIZ1 in ESCC in the Indian
Externí odkaz:
https://doaj.org/article/5450dd0fee2f48be8f05fa0c1f4c1dcf
Autor:
Abhisek Dwivedy, Richard Mariadasse, Mohammed Ahmad, Sayan Chakraborty, Deepsikha Kar, Satish Tiwari, Sankar Bhattacharyya, Sudipta Sonar, Shailendra Mani, Prafullakumar Tailor, Tanmay Majumdar, Jeyaraman Jeyakanthan, Bichitra Kumar Biswal
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009384 (2021)
Apart from the canonical fingers, palm and thumb domains, the RNA dependent RNA polymerases (RdRp) from the viral order Nidovirales possess two additional domains. Of these, the function of the Nidovirus RdRp associated nucleotidyl transferase domain
Externí odkaz:
https://doaj.org/article/8a0f376e1e0445a3af0361e1e121e216
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100161- (2020)
Summary: We describe a protocol for a long-term co-culture assay to study the contribution of mesenchymal stromal cells (MSCs) in regulating hematopoietic stem/progenitor cell (HSPC) activity. In addition, we describe the use of a clonogenic assay to
Externí odkaz:
https://doaj.org/article/405d262d07dc40c4a07cb98e3a4d3270
Autor:
Sayan Chakraborty, Kizito Njah, Ajaybabu V. Pobbati, Ying Bena Lim, Anandhkumar Raju, Manikandan Lakshmanan, Vinay Tergaonkar, Chwee Teck Lim, Wanjin Hong
Publikováno v:
Cell Reports, Vol 18, Iss 10, Pp 2464-2479 (2017)
The Hippo pathway effectors YAP and TAZ act as nuclear sensors of mechanical signals in response to extracellular matrix (ECM) cues. However, the identity and nature of regulators in the ECM and the precise pathways relaying mechanoresponsive signals
Externí odkaz:
https://doaj.org/article/7b021c8bd89649e6a60d9fe4ba9eca46
Publikováno v:
Mathematics, Vol 8, Iss 7, p 1084 (2020)
Dynamic models of physical systems often contain parameters that must be estimated from experimental data. In this work, we consider the identification of parameters in nonlinear mechanical systems given noisy measurements of only some states. The re
Externí odkaz:
https://doaj.org/article/a50dcaba12b3485eb36f169679a04c0f
Publikováno v:
Entropy, Vol 22, Iss 6, p 659 (2020)
Image registration has an imperative role in medical imaging. In this work, a grey-wolf optimizer (GWO)-based non-rigid demons registration is proposed to support the retinal image registration process. A comparative study of the proposed GWO-based d
Externí odkaz:
https://doaj.org/article/1512120937a744da983540cbb6519b22
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175317 (2017)
Tracheary Element Differentiation Inhibitory Factor (TDIF) belongs to the family of post-translationally modified CLE (CLAVATA3/embryo surrounding region (ESR)-related) peptide hormones that control root growth and define the delicate balance between
Externí odkaz:
https://doaj.org/article/4f836a29529f440ab6ea0931e28af45d