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pro vyhledávání: '"Saya Mitsuoka"'
Autor:
Tadashi Kasahara, Junya Yamamoto, Rika Ohkubo, Isao Ishii, Yumi Abiko, Norihiko Okada, Noriyuki Akahoshi, Saya Mitsuoka, Yoshifumi Hagiya, Hidenori Yamada, Saori Yoshida, Shotaro Kamata, Yoshito Kumagai
Publikováno v:
Toxicology and Applied Pharmacology. 282:195-206
The key mechanism for acetaminophen hepatotoxicity is cytochrome P450 (CYP)-dependent formation of N-acetyl-p-benzoquinone imine, a potent electrophile that forms protein adducts. Previous studies revealed the fundamental role of glutathione, which b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12067721fc841091708e7e89a7a2113a
https://doi.org/10.1016/j.taap.2014.11.015
https://doi.org/10.1016/j.taap.2014.11.015
