Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Saya Kishimoto"'
Lactobacillus paracasei subsp. paracasei 2004 improves health and lifespan in Caenorhabditis elegans
Autor:
Saya Kishimoto, Masanori Nono, Yutaka Makizaki, Yoshiki Tanaka, Hiroshi Ohno, Eisuke Nishida, Masaharu Uno
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Recent research has highlighted the importance of the gut microbiome in regulating aging, and probiotics are interventions that can promote gut health. In this study, we surveyed several novel lactic acid bacteria to examine their beneficial
Externí odkaz:
https://doaj.org/article/7ac2d4bf3b534356a277d718c3490080
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Okabe et al. show that the miRNA production system in the neuron and the small RNA transport machinery in the intestine are required for the acquisition of hormesis. For its inheritance, both the transport of small RNAs in the germline and the germli
Externí odkaz:
https://doaj.org/article/c8b4e77b94f946d6bef7dc612bea48de
Autor:
Masaharu Uno, Yuri Tani, Masanori Nono, Emiko Okabe, Saya Kishimoto, Chika Takahashi, Ryoji Abe, Takuya Kurihara, Eisuke Nishida
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102706- (2021)
Summary: Previous studies have revealed the importance of inter-tissue communications for lifespan regulation. However, the inter-tissue network responsible for lifespan regulation is not well understood, even in a simple organism Caenorhabditis eleg
Externí odkaz:
https://doaj.org/article/dd64db2682e5411ba3d41d001684278b
Publikováno v:
Inflammation and Regeneration, Vol 38, Iss 1, Pp 1-7 (2018)
Abstract Throughout life, organisms are subjected to a variety of environmental perturbations, including temperature, nutrient conditions, and chemical agents. Exposure to external signals induces diverse changes in the physiological conditions of or
Externí odkaz:
https://doaj.org/article/fff7431d679445f6a50ee4a3ae690984
Autor:
Masanori Nono, Saya Kishimoto, Aya Sato-Carlton, Peter Mark Carlton, Eisuke Nishida, Masaharu Uno
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3207-3217.e4 (2020)
Summary: Changes in epigenetic states affect organismal homeostasis, including stress resistance. However, the mechanisms coordinating epigenetic states and systemic stress resistance remain largely unknown. Here, we identify the intestine-to-germlin
Externí odkaz:
https://doaj.org/article/82ea2337d40a4822b7ab35454ec48e53
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Environmental stress causes epigenetic changes but it is unclear if such changes are transgenerational. Here, the authors show that inC. elegans, increased resistance to oxidative stress and proteotoxicity in the parental generation and linked epigen
Externí odkaz:
https://doaj.org/article/2cfa6694c128467cb5b608ec7dd399ec
Autor:
Masaharu Uno, Sakiko Honjoh, Mitsuhiro Matsuda, Haruka Hoshikawa, Saya Kishimoto, Tomohito Yamamoto, Miki Ebisuya, Takuya Yamamoto, Kunihiro Matsumoto, Eisuke Nishida
Publikováno v:
Cell Reports, Vol 3, Iss 1, Pp 79-91 (2013)
Intermittent fasting is one of the most effective dietary restriction regimens that extend life span in C. elegans and mammals. Fasting-stimulus responses are key to the longevity response; however, the mechanisms that sense and transduce the fasting
Externí odkaz:
https://doaj.org/article/c3261fa0c69141cdaf73ec30cc7ef10d
Autor:
Saya Kishimoto, Masanori Nono, Ryoji Abe, Emiko Okabe, Yuri Tani, Masaharu Uno, Eisuke Nishida, Takuya Kurihara, Chika Takahashi
Publikováno v:
iScience
iScience, Vol 24, Iss 7, Pp 102706-(2021)
iScience, Vol 24, Iss 7, Pp 102706-(2021)
Summary Previous studies have revealed the importance of inter-tissue communications for lifespan regulation. However, the inter-tissue network responsible for lifespan regulation is not well understood, even in a simple organism Caenorhabditis elega
Publikováno v:
Inflammation and Regeneration, Vol 38, Iss 1, Pp 1-7 (2018)
Inflammation and Regeneration
Inflammation and Regeneration
Throughout life, organisms are subjected to a variety of environmental perturbations, including temperature, nutrient conditions, and chemical agents. Exposure to external signals induces diverse changes in the physiological conditions of organisms.
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Environmental conditions can cause phenotypic changes, part of which can be inherited by subsequent generations via soma-to-germline communication. However, the signaling molecules or pathways that mediate intertissue communication remain unclear. He