Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Say Li Kong"'
Autor:
Omkar Chandra, Madhu Sharma, Neetesh Pandey, Indra Prakash Jha, Shreya Mishra, Say Li Kong, Vibhor Kumar
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3590-3603 (2023)
Understanding the biological roles of all genes only through experimental methods is challenging. A computational approach with reliable interpretability is needed to infer the function of genes, particularly for non-coding RNAs. We have analyzed gen
Externí odkaz:
https://doaj.org/article/1935610f724b452289021da80c17e778
Autor:
Joanna Hui Juan Tan, Say Li Kong, Joyce A. Tai, Huay Mei Poh, Fei Yao, Yee Yen Sia, Edwin Kok Hao Lim, Angela Maria Takano, Daniel Shao-Weng Tan, Asif Javed, Axel M. Hillmer
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 343-354 (2021)
Single cell genomics offers an unprecedented resolution to interrogate genetic heterogeneity in a patient’s tumour at the intercellular level. However, the DNA yield per cell is insufficient for today’s sequencing library preparation protocols. T
Externí odkaz:
https://doaj.org/article/19ec162017024374b03cd375a1fa8903
Autor:
Say Li Kong, Xingliang Liu, Swee Jin Tan, Joyce A. Tai, Ler Yee Phua, Huay Mei Poh, Trifanny Yeo, Yong Wei Chua, Yu Xuan Haw, Wen Huan Ling, Raymond Chee Hui Ng, Tira J. Tan, Kiley Wei Jen Loh, Daniel Shao-Weng Tan, Quan Sing Ng, Mei Kim Ang, Chee Keong Toh, Yi Fang Lee, Chwee Teck Lim, Tony Kiat Hon Lim, Axel M. Hillmer, Yoon Sim Yap, Wan-Teck Lim
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
IntroductionCirculating tumor cells (CTCs) and cell-free tumor DNA (ctDNA) are tumor components present in circulation. Due to the limited access to both CTC enrichment platforms and ctDNA sequencing in most laboratories, they are rarely analyzed tog
Externí odkaz:
https://doaj.org/article/b70ad78864ef47c3b413d596470674f7
Autor:
Hui Cheng, Heather Yin-Kuan Ang, Chadi A. EL Farran, Pin Li, Hai Tong Fang, Tong Ming Liu, Say Li Kong, Michael Lingzi Chin, Wei Yin Ling, Edwin Kok Hao Lim, Hu Li, Tara Huber, Kyle M. Loh, Yuin-Han Loh, Bing Lim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Direct reprogramming of closely-related lineages can generate hematopoietic stem cells. Here, the authors show hematopoietic transcription factors Scl, Lmo2, Runx1 and Bmi1 can reprogram fibroblasts into induced hematopoietic progenitors (iHPs), whic
Externí odkaz:
https://doaj.org/article/7d2ce78d316b47009ea53ac3b86aacc1
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-14 (2011)
Abstract Despite the role of the estrogen receptor α (ERα) pathway as a key growth driver for breast cells, the phenotypic consequence of exogenous introduction of ERα into ERα‐negative cells paradoxically has been growth inhibition. We mapped
Externí odkaz:
https://doaj.org/article/83e90841a67e400ea6ee057a7d0b34ac
Autor:
Roy Joseph, Yuriy L Orlov, Mikael Huss, Wenjie Sun, Say Li Kong, Leena Ukil, You Fu Pan, Guoliang Li, Michael Lim, Jane S Thomsen, Yijun Ruan, Neil D Clarke, Shyam Prabhakar, Edwin Cheung, Edison T Liu
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-13 (2010)
Abstract A major question in transcription factor (TF) biology is why a TF binds to only a small fraction of motif eligible binding sites in the genome. Using the estrogen receptor‐α as a model system, we sought to explicitly define parameters tha
Externí odkaz:
https://doaj.org/article/7bdfe7fe36ae4c3688f07e0338e42aab
Autor:
Chin-Yo Lin, Vinsensius B Vega, Jane S Thomsen, Tao Zhang, Say Li Kong, Min Xie, Kuo Ping Chiu, Leonard Lipovich, Daniel H Barnett, Fabio Stossi, Ailing Yeo, Joshy George, Vladimir A Kuznetsov, Yew Kok Lee, Tze Howe Charn, Nallasivam Palanisamy, Lance D Miller, Edwin Cheung, Benita S Katzenellenbogen, Yijun Ruan, Guillaume Bourque, Chia-Lin Wei, Edison T Liu
Publikováno v:
PLoS Genetics, Vol 3, Iss 6, p e87 (2007)
Using a chromatin immunoprecipitation-paired end diTag cloning and sequencing strategy, we mapped estrogen receptor alpha (ERalpha) binding sites in MCF-7 breast cancer cells. We identified 1,234 high confidence binding clusters of which 94% are proj
Externí odkaz:
https://doaj.org/article/c5d23618fafe47a999d02e29af566afb
Autor:
Xiubo Fan, Chin Teck Ng, Dianyang Guo, Frances Lim, Jia Chi Tan, Annie Law, Lim Hee Goh, Zhi Yong Poon, Alice Cheung, Say Li Kong, Michelle Tan, Shang Li, Alwin Loh, Anne James, Tony Lim, Jinmiao Chen, Julian Thumboo, William Hwang, Andrea Low
Publikováno v:
Arthritis & Rheumatology. 75:553-566
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21023613e8be5edc80dc6aa0eb77061e
https://doi.org/10.1002/art.42383
https://doi.org/10.1002/art.42383
Autor:
Omkar Chandra, Madhu Sharma, Neetesh Pandey, Indra Prakash Jha, Shreya Mishra, Say Li Kong, Vibhor Kumar
The number of annotated genes in the human genome has increased tremendously, and understanding their biological role is challenging through experimental methods alone. There is a need for a computational approach to infer the function of genes, part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52b99763eda15995e07ab0bf0f2d4152
https://doi.org/10.1101/2022.04.17.488570
https://doi.org/10.1101/2022.04.17.488570
Autor:
Huipeng Li, Elise T. Courtois, Debarka Sengupta, Yuliana Tan, Kok Hao Chen, Jolene Jie Lin Goh, Say Li Kong, Clarinda Chua, Lim Kiat Hon, Wah Siew Tan, Mark Wong, Paul Jongjoon Choi, Lawrence J. K. Wee, Axel M. Hillmer, Iain Beehuat Tan, Paul Robson, Shyam Prabhakar
Publikováno v:
Nature Genetics. 55:166-166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea8f50686371a3591e5684dac4475739
https://doi.org/10.1038/s41588-022-01281-y
https://doi.org/10.1038/s41588-022-01281-y