Výsledky vyhledávání - "Sawsan H. Alelaiwi"

Akademický článek

One-Pot Synthesis of Aminated Benzo-Fused Heterocycles and N‑Substituted Dibenzothiophenes via Copper-Catalyzed Ullmann Type Reaction

Autor: Sawsan H. Alelaiwi, James R. McKee

Publikováno v: ACS Omega, Vol 6, Iss 8, Pp 6009-6016 (2021)

Externí odkaz: https://doaj.org/article/cf4e6bc700354ddfb96472ac300d0a1f

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One-Pot Synthesis of Aminated Benzo-Fused Heterocycles and N-Substituted Dibenzothiophenes via Copper-Catalyzed Ullmann Type Reaction

Autor: James R. McKee, Sawsan H. Alelaiwi

Publikováno v: ACS Omega, Vol 6, Iss 8, Pp 6009-6016 (2021)
ACS Omega

We report here a direct and effective method to synthesize a primary amine of several polycyclic aromatic compounds. This reaction has been achieved through copper (I)-catalyzed Ullmann C–N coupling. Furthermore, this strategy allows the synthesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47498aafd1abfb290120567571a28325
https://doi.org/10.1021/acsomega.1c00414

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Structure–activity relationship of 2-aminodibenzothiophene pharmacophore and the discovery of aminobenzothiophenes as potent inhibitors of Mycobacterium smegmatis

Autor: Sawsan H. Alelaiwi, Jason E. Heindl, Vignesh Sivaganesh, Bela Peethambaran, James R. McKee

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 63:128650

Tuberculosis (TB) is one of the deadliest infectious diseases worldwide and its current treatments have been complicated with the emergence of multi-drug resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains. Therefore, the discovery of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae293c9db4fa78ff576601d0a6bf90f
https://doi.org/10.1016/j.bmcl.2022.128650

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